Protein: SYDM
Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)

Gene: SYDM, DARS2
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q6PI48

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0004815 - aspartate-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

499847

CH60
60 kDa heat shock protein, mitochondrial

4

1

High-throughput

0.697

High

325236

AIFM1
Apoptosis-inducing factor 1, mitochondrial

4

1

High-throughput

0.683

High

1161611

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.656

High

1065529

SYK
Lysine--tRNA ligase

1

12

Small-scale

0.621

High

651487

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.618

High

720734

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.618

High

1161613

MTG2
Mitochondrial ribosome-associated GTPase 2

2

2

High-throughput

0.611

High

856709

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.602

High

227805

PRKN
E3 ubiquitin-protein ligase parkin

2

10

High-throughput

0.584

High

873437

P5CS
Delta-1-pyrroline-5-carboxylate synthase

2

0

High-throughput

0.580

High

147757

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

2

2

High-throughput

0.567

High

1026297

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

4

Small-scale

0.555

High

1161580

TSN33
Tetraspanin-33

2

1

High-throughput

0.553

High

529285

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.541

High

665487

EPHA8
Ephrin type-A receptor 8

1

5

High-throughput

0.541

High

885165

FOXL2
Forkhead box protein L2

1

5

High-throughput

0.536

High

1161586

CBR4
3-oxoacyl-[acyl-carrier-protein] reductase

1

3

High-throughput

0.536

High

1161606

MYL10
Myosin regulatory light chain 10

1

1

High-throughput

0.536

High

1161620

DIC
Mitochondrial dicarboxylate carrier

1

1

High-throughput

0.536

High

1161625

MRM2
rRNA methyltransferase 2, mitochondrial

1

1

High-throughput

0.536

High

1161628

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1161629

RT02
Small ribosomal subunit protein uS2m

1

4

High-throughput

0.536

High

258727

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

270926

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

0

High-throughput

0.513

High

272361

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.513

High

646420

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

790260

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.513

High

815388

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

1156314

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

0

High-throughput

0.513

High

1159890

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

1161578

RM21
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.513

High

1161583

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1161584

ETKMT
Electron transfer flavoprotein beta subunit lysine methyltransferase

1

0

High-throughput

0.513

High

1161592

GLYL1
Glycine N-acyltransferase-like protein 1

1

0

High-throughput

0.513

High

1161598

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1161605

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.513

High

1161608

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.513

High

1161609

LDH6B
L-lactate dehydrogenase A-like 6B

1

0

High-throughput

0.513

High

1161615

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.513

High

1161617

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

1

0

High-throughput

0.513

High

1161621

NPS3A
Protein NipSnap homolog 3A

1

0

High-throughput

0.513

High

1161624

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

1161604

DPYL5
Dihydropyrimidinase-related protein 5

1

2

High-throughput

0.494

High

1161600

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.493

High

270802

FOXH1
Forkhead box protein H1

1

5

High-throughput

0.489

High

813552

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.489

High

957127

SHC2
SHC-transforming protein 2

1

5

High-throughput

0.489

High

1021305

FOXL1
Forkhead box protein L1

1

5

High-throughput

0.489

High

1161576

FOXI2
Forkhead box protein I2

1

5

High-throughput

0.489

High

1161595

TRI43
Tripartite motif-containing protein 43

1

1

High-throughput

0.489

High

1161601

RSLAB
Ras-like protein family member 10B

1

2

High-throughput

0.489

High

1161603

FOXB1
Forkhead box protein B1

1

6

High-throughput

0.489

High

1161627

KLH20
Kelch-like protein 20

1

1

High-throughput

0.489

High

294943

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

347089

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

379517

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.479

High

385024

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.479

High

440578

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

3

High-throughput

0.479

High

497195

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.479

High

552985

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

674464

UFO
Tyrosine-protein kinase receptor UFO

1

8

High-throughput

0.479

High

718939

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

803142

IF2M
Translation initiation factor IF-2, mitochondrial

1

8

High-throughput

0.479

High

824119

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.479

High

1020464

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

7

High-throughput

0.479

High

1029543

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

1035834

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1041840

CUL3
Cullin-3

1

7

High-throughput

0.479

High

1045783

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

1064417

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1066276

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1067991

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

1128158

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

1161579

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.479

High

1161596

OPTN
Optineurin

1

3

High-throughput

0.479

High

1161602

DNJC2
DnaJ homolog subfamily C member 2

1

4

High-throughput

0.479

High

1161618

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

779615

CCNF
Cyclin-F

1

3

High-throughput

0.470

High

1118826

Q4VAQ0
COL8A2 protein

1

1

High-throughput

0.470

High

1161610

THS7B
Thrombospondin type-1 domain-containing protein 7B

1

1

High-throughput

0.470

High

262855

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

486554

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

981298

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

990127

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1036672

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1074925

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.458

High

1086621

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1152865

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1161582

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1161593

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

1161594

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

1161607

TR61B
tRNA

1

0

High-throughput

0.458

High

1161622

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

0

High-throughput

0.458

High

626319

CO8A2
Collagen alpha-2(VIII) chain

1

1

High-throughput

0.439

High

298596

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.437

High

900598

RHOA
Transforming protein RhoA

1

1

High-throughput

0.437

High

1140540

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

1161575

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1161577

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1161585

RHG24
Rho GTPase-activating protein 24

1

1

High-throughput

0.437

High

1161614

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1145800

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.426

High

1161612

GCP60
Golgi resident protein GCP60

1

0

Small-scale

0.426

High

1161587

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

885873

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.328

High

1161626

LAMP3
Lysosome-associated membrane glycoprotein 3

2

0

High-throughput

0.328

High

153325

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.316

High

828113

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

0

High-throughput

0.316

High

982743

PLP2
Proteolipid protein 2

2

0

High-throughput

0.316

High

1088345

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.316

High

1121574

UNC50
Protein unc-50 homolog

2

0

High-throughput

0.316

High

1161591

TM239
Transmembrane protein 239

2

0

High-throughput

0.316

High

1161623

FETUB
Fetuin-B

2

0

High-throughput

0.316

High

326328

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.279

Low

677834

LCN1
Lipocalin-1

1

0

High-throughput

0.279

Low

1161589

BBS1
Bardet-Biedl syndrome 1 protein

1

0

High-throughput

0.279

Low

1161590

CC4L
C-C motif chemokine 4-like

1

0

High-throughput

0.279

Low

1161599

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.279

Low

1161616

CT096
Uncharacterized protein C20orf96

1

0

High-throughput

0.279

Low

1161619

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

1161588

FBX15
F-box only protein 15

1

0

High-throughput

0.269

Low

976228

UPAR
Urokinase plasminogen activator surface receptor

1

0

High-throughput

0.249

Low

1085305

FSCN1
Fascin

1

0

High-throughput

0.249

Low

1101123

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1161581

Q86V94
LOC554223 protein

1

0

High-throughput

0.249

Low

1161597

ARHGQ
Rho guanine nucleotide exchange factor 26

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024