Protein: PELI3
E3 ubiquitin-protein ligase pellino homolog 3 (Pellino-3) (EC 2.3.2.27)

Gene: PELI3
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q8N2H9

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0008592 - regulation of Toll signaling pathway
GO:0010804 - negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0045087 - innate immune response
GO:0061630 - ubiquitin protein ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848422

IRAK1
Interleukin-1 receptor-associated kinase 1

8

10

Small-scale

0.746

High

1231628

TRAF6
TNF receptor-associated factor 6

5

3

Small-scale

0.718

High

201366

M3K7
Mitogen-activated protein kinase kinase kinase 7

3

4

Small-scale

0.650

High

871665

HSP72
Heat shock-related 70 kDa protein 2

2

3

High-throughput

0.621

High

1231619

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

0

High-throughput

0.607

High

201815

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

2

Small-scale

0.578

High

504389

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.536

High

564123

HSP76
Heat shock 70 kDa protein 6

1

3

High-throughput

0.536

High

770925

TCPZ
T-complex protein 1 subunit zeta

1

2

High-throughput

0.536

High

943346

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.536

High

1175026

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.536

High

1231618

TCPW
T-complex protein 1 subunit zeta-2

1

2

High-throughput

0.536

High

428303

TBB5
Tubulin beta chain

1

0

High-throughput

0.513

High

1039001

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

0

High-throughput

0.513

High

1231622

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.513

High

1231627

RUVB1
RuvB-like 1

1

0

High-throughput

0.513

High

896491

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

4

Small-scale

0.501

High

1033119

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

5

Small-scale

0.501

High

609679

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

0

High-throughput

0.493

High

1231621

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

0

Small-scale

0.493

High

780745

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

High-throughput

0.493

High

829397

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

1231620

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.481

High

1231623

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.481

High

395166

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

197906

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

11

Small-scale

0.479

High

1231624

IRAK4
Interleukin-1 receptor-associated kinase 4

1

2

Small-scale

0.479

High

265539

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.470

High

1231625

DNJB4
DnaJ homolog subfamily B member 4

1

0

High-throughput

0.458

High

1231626

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

High-throughput

0.458

High

483793

HS71B
Heat shock 70 kDa protein 1B

1

3

High-throughput

0.445

High

815396

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

Small-scale

0.437

High

1144708

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

1

High-throughput

0.437

High

150382

ZN195
Zinc finger protein 195

1

0

High-throughput

0.279

Low

674768

AA1R
Adenosine receptor A1

1

0

High-throughput

0.279

Low

1150530

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.279

Low

1012414

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024