Protein: FA8
Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]

Gene: FA8, F8
Organism: Homo sapiens
Interactions: 25
UniProt ID: P00451

Gene Ontology (top 5):
GO:0005507 - copper ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0005796 - Golgi lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

336804

VWF
von Willebrand factor

4

3

Small-scale

0.893

High

336799

FA8
Coagulation factor VIII

1

11

Small-scale

0.647

High

336803

KV320
Immunoglobulin kappa variable 3-20

1

0

Small-scale

0.614

High

336815

RYBP
RING1 and YY1-binding protein

2

2

High-throughput

0.567

High

336801

FA9
Coagulation factor IX

1

14

Small-scale

0.527

High

336806

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.515

High

336800

THRB
Prothrombin

1

10

Small-scale

0.501

High

336802

FA10
Coagulation factor X

1

13

Small-scale

0.501

High

336805

PROS
Vitamin K-dependent protein S

1

9

Small-scale

0.501

High

336818

GGA1
ADP-ribosylation factor-binding protein GGA1

1

2

High-throughput

0.494

High

336819

UBQL1
Ubiquilin-1

1

2

High-throughput

0.481

High

336813

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

Small-scale

0.480

High

336814

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

1

0

Small-scale

0.480

High

336809

CALX
Calnexin

1

6

Small-scale

0.479

High

336810

LMAN1
Protein ERGIC-53

1

1

Small-scale

0.479

High

336816

MAGB6
Melanoma-associated antigen B6

1

1

High-throughput

0.470

High

336807

HIS3
Histatin-3

1

0

Small-scale

0.458

High

256793

T22D2
TSC22 domain family protein 2

1

1

Small-scale

0.439

High

336808

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.437

High

156657

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

Small-scale

0.299

High

336812

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.269

Low

239470

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

336811

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.249

Low

336817

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024