Protein: EI2BB
Translation initiation factor eIF2B subunit beta (S20I15) (S20III15) (eIF2B GDP-GTP exchange factor subunit beta)

Gene: EI2BB, EIF2B2
Organism: Homo sapiens
Interactions: 99
UniProt ID: P49770

Gene Ontology (top 5):
GO:0001541 - ovarian follicle development
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834459

EI2BD
Translation initiation factor eIF2B subunit delta

8

15

High-throughput

0.971

High

834410

EI2BA
Translation initiation factor eIF2B subunit alpha

4

14

Small-scale

0.895

High

834456

EI2BG
Translation initiation factor eIF2B subunit gamma

3

14

High-throughput

0.861

High

834408

EI2BE
Translation initiation factor eIF2B subunit epsilon

4

18

Small-scale

0.696

High

834444

CI072
Guanine nucleotide exchange factor C9orf72

4

2

High-throughput

0.690

High

834451

OPN3
Opsin-3

3

4

High-throughput

0.667

High

834457

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

2

High-throughput

0.667

High

474960

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

2

High-throughput

0.628

High

599554

SYT1
Synaptotagmin-1

2

4

High-throughput

0.628

High

600530

EPHA1
Ephrin type-A receptor 1

2

4

High-throughput

0.628

High

834403

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

3

High-throughput

0.628

High

793625

DCC
Netrin receptor DCC

2

2

Small-scale

0.611

High

834448

P2RX4
P2X purinoceptor 4

2

2

High-throughput

0.611

High

686796

GP183
G-protein coupled receptor 183

3

6

High-throughput

0.609

High

793084

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

9

High-throughput

0.609

High

834400

EFNB2
Ephrin-B2

3

4

High-throughput

0.609

High

834429

STX12
Syntaxin-12

3

2

High-throughput

0.609

High

834445

NECT4
Nectin-4

3

5

High-throughput

0.609

High

834462

CAH14
Carbonic anhydrase 14

3

2

High-throughput

0.609

High

161507

S27A2
Long-chain fatty acid transport protein 2

2

0

High-throughput

0.602

High

834413

VAMP3
Vesicle-associated membrane protein 3

2

0

High-throughput

0.602

High

338129

EGFR
Epidermal growth factor receptor

2

4

High-throughput

0.584

High

409769

GLPB
Glycophorin-B

2

2

High-throughput

0.574

High

834432

SIGL1
SIGLEC family-like protein 1

2

2

High-throughput

0.574

High

834434

GOLM1
Golgi membrane protein 1

2

1

High-throughput

0.574

High

834464

EXOG
Nuclease EXOG, mitochondrial

2

3

High-throughput

0.574

High

556501

LEUK
Leukosialin

2

2

High-throughput

0.558

High

826569

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.541

High

454689

TACD2
Tumor-associated calcium signal transducer 2

1

2

High-throughput

0.536

High

607752

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

1

High-throughput

0.536

High

649378

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

780630

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

7

High-throughput

0.536

High

834401

IF5
Eukaryotic translation initiation factor 5

1

7

High-throughput

0.536

High

834404

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.536

High

834405

EFNB1
Ephrin-B1

1

4

High-throughput

0.536

High

834406

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

1

High-throughput

0.536

High

834411

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.536

High

834423

BTNL9
Butyrophilin-like protein 9

1

3

High-throughput

0.536

High

834440

FGF14
Fibroblast growth factor 14

1

1

High-throughput

0.536

High

834463

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

2

High-throughput

0.536

High

834465

E41L3
Band 4.1-like protein 3

1

1

High-throughput

0.536

High

834466

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

1

High-throughput

0.536

High

834402

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.513

High

834449

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.513

High

238850

TPST2
Protein-tyrosine sulfotransferase 2

1

2

High-throughput

0.489

High

452678

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

626774

PTAFR
Platelet-activating factor receptor

1

8

High-throughput

0.489

High

639561

TNR5
Tumor necrosis factor receptor superfamily member 5

1

2

High-throughput

0.489

High

702203

CD70
CD70 antigen

1

1

High-throughput

0.489

High

714913

BTC
Probetacellulin [Cleaved into: Betacellulin

1

2

High-throughput

0.489

High

834409

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

9

High-throughput

0.489

High

834412

CD226
CD226 antigen

1

6

High-throughput

0.489

High

834421

GOLM2
Protein GOLM2

1

1

High-throughput

0.489

High

834425

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

834427

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

2

High-throughput

0.489

High

834431

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

834433

SYT2
Synaptotagmin-2

1

4

High-throughput

0.489

High

834438

F174A
Membrane protein FAM174A

1

1

High-throughput

0.489

High

834439

CLC2B
C-type lectin domain family 2 member B

1

4

High-throughput

0.489

High

834447

SEC62
Translocation protein SEC62

1

2

High-throughput

0.489

High

834454

PACC1
Proton-activated chloride channel

1

1

High-throughput

0.489

High

834455

PCDH9
Protocadherin-9

1

1

High-throughput

0.489

High

834460

CC018
Uncharacterized protein C3orf18

1

2

High-throughput

0.489

High

586623

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.481

High

394343

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

162516

XPO1
Exportin-1

1

9

High-throughput

0.479

High

226862

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

294536

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

417196

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

455218

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

834419

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

834424

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

834426

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

834443

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

834453

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

834458

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

834461

AGO1
Protein argonaute-1

1

1

High-throughput

0.479

High

834467

5MP1
eIF5-mimic protein 1

1

9

High-throughput

0.479

High

834416

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

834415

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

834428

STING
Stimulator of interferon genes protein

1

1

Small-scale

0.445

High

834446

CK5P2
CDK5 regulatory subunit-associated protein 2

1

3

High-throughput

0.445

High

834442

MR1L1
MORF4 family-associated protein 1-like 1

1

2

High-throughput

0.439

High

552232

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

650673

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

719970

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

834422

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

834430

PNKD
Probable hydrolase PNKD

1

1

High-throughput

0.437

High

834436

MCU
Calcium uniporter protein, mitochondrial

1

2

High-throughput

0.437

High

834441

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.437

High

834452

EMRE
Essential MCU regulator, mitochondrial

1

2

High-throughput

0.437

High

834407

NTCP7
Sodium/bile acid cotransporter 7

2

0

High-throughput

0.328

High

834417

MFS4B
Sodium-dependent glucose transporter 1

2

0

High-throughput

0.328

High

834435

B3GL2
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.328

High

834420

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.288

High

834414

ZN326
DBIRD complex subunit ZNF326

1

0

High-throughput

0.279

Low

834418

TM164
Transmembrane protein 164

1

0

High-throughput

0.279

Low

834437

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.279

Low

834450

PCGF6
Polycomb group RING finger protein 6

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024