Protein: RHXF2
Rhox homeobox family member 2 (Paired-like homeobox protein PEPP-2) (Testis homeobox gene 1)

Gene: RHXF2, RHOXF2
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q9BQY4

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1410982

RHXF2
Rhox homeobox family member 2

3

15

High-throughput

0.860

High

210105

CRX
Cone-rod homeobox protein

2

19

High-throughput

0.783

High

330292

VENTX
Homeobox protein VENTX

2

18

High-throughput

0.783

High

772199

MSX2
Homeobox protein MSX-2

2

20

High-throughput

0.783

High

1407365

NKX31
Homeobox protein Nkx-3.1

2

19

High-throughput

0.783

High

1410997

ZBT32
Zinc finger and BTB domain-containing protein 32

6

7

High-throughput

0.729

High

1139122

DAZP2
DAZ-associated protein 2

5

2

High-throughput

0.728

High

1372053

RBPMS
RNA-binding protein with multiple splicing

4

2

High-throughput

0.705

High

725188

HXC13
Homeobox protein Hox-C13

1

20

High-throughput

0.698

High

1005638

PITX1
Pituitary homeobox 1

1

18

High-throughput

0.698

High

1410988

NANOG
Homeobox protein NANOG

1

19

High-throughput

0.698

High

211407

RFOX2
RNA binding protein fox-1 homolog 2

4

3

High-throughput

0.692

High

1151057

PCH2
Pachytene checkpoint protein 2 homolog

4

0

High-throughput

0.677

High

1381896

TET5B
Terminal nucleotidyltransferase 5B

3

4

High-throughput

0.667

High

1410999

MAGD1
Melanoma-associated antigen D1

3

0

High-throughput

0.646

High

927519

ATX1
Ataxin-1

2

9

High-throughput

0.639

High

1410991

RFOX1
RNA binding protein fox-1 homolog 1

2

3

High-throughput

0.636

High

1410995

NKX12
NK1 transcription factor-related protein 2

1

19

High-throughput

0.621

High

1133159

LASP1
LIM and SH3 domain protein 1

3

4

High-throughput

0.616

High

1186907

KR195
Keratin-associated protein 19-5

3

1

High-throughput

0.616

High

1187912

KR197
Keratin-associated protein 19-7

3

2

High-throughput

0.616

High

1005030

RNF4
E3 ubiquitin-protein ligase RNF4

2

2

High-throughput

0.606

High

1040642

CREM
cAMP-responsive element modulator

2

5

High-throughput

0.606

High

1213537

UBAP2
Ubiquitin-associated protein 2

2

18

High-throughput

0.606

High

1253981

RBPS2
RNA-binding protein with multiple splicing 2

2

2

High-throughput

0.606

High

1315885

ZN683
Tissue-resident T-cell transcription regulator protein ZNF683

2

4

High-throughput

0.606

High

1410989

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

2

6

High-throughput

0.606

High

2912

A0A0C4DGF1
Zinc finger and BTB domain containing 32

3

1

High-throughput

0.597

High

1235270

CMI2A
Ciliary microtubule inner protein 2A

2

0

High-throughput

0.580

High

1281087

KHDC4
KH homology domain-containing protein 4

2

0

High-throughput

0.580

High

1407063

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

1410996

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

0

High-throughput

0.580

High

991413

SUMO1
Small ubiquitin-related modifier 1

1

4

High-throughput

0.573

High

1044702

ARI5A
AT-rich interactive domain-containing protein 5A

1

20

High-throughput

0.573

High

1061847

TLE5
TLE family member 5

1

20

High-throughput

0.573

High

1218987

TET5C
Terminal nucleotidyltransferase 5C

1

4

High-throughput

0.573

High

1358655

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

3

High-throughput

0.573

High

1410992

HYPK
Huntingtin-interacting protein K

2

0

Small-scale

0.561

High

50350

F168B
Myelin-associated neurite-outgrowth inhibitor

2

1

High-throughput

0.553

High

820733

CEAM6
Cell adhesion molecule CEACAM6

2

2

High-throughput

0.553

High

948378

KR122
Keratin-associated protein 12-2

2

3

High-throughput

0.553

High

1186595

KRA61
Keratin-associated protein 6-1

2

1

High-throughput

0.553

High

1186695

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.553

High

1186973

KR151
Keratin-associated protein 15-1

2

3

High-throughput

0.553

High

1186991

KR134
Keratin-associated protein 13-4

2

3

High-throughput

0.553

High

1198040

KR132
Keratin-associated protein 13-2

2

3

High-throughput

0.553

High

1212686

GT253
Inactive glycosyltransferase 25 family member 3

2

1

High-throughput

0.553

High

1307114

KRA71
Keratin-associated protein 7-1

2

1

High-throughput

0.553

High

1364815

F168A
Protein FAM168A

2

1

High-throughput

0.553

High

1408444

TEP1
Telomerase protein component 1

2

5

High-throughput

0.553

High

928334

ATN1
Atrophin-1

1

20

High-throughput

0.552

High

159824

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.541

High

297028

CCNK
Cyclin-K

1

3

High-throughput

0.541

High

1033191

EWS
RNA-binding protein EWS

1

6

High-throughput

0.541

High

1400244

LENG8
Leukocyte receptor cluster member 8

1

6

High-throughput

0.541

High

251958

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

1

High-throughput

0.532

High

351593

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

1

High-throughput

0.532

High

286406

DAB1
Disabled homolog 1

1

4

High-throughput

0.523

High

219509

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.518

High

943302

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.518

High

1016371

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.518

High

1410983

VPS25
Vacuolar protein-sorting-associated protein 25

1

0

High-throughput

0.518

High

1410985

RAMAC
RNA guanine-N7 methyltransferase activating subunit

1

0

High-throughput

0.518

High

1160373

OBF1
POU domain class 2-associating factor 1

1

1

High-throughput

0.494

High

1289288

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

4

High-throughput

0.494

High

1324451

CLASR
CLK4-associating serine/arginine rich protein

1

2

High-throughput

0.494

High

1337509

TET5D
Terminal nucleotidyltransferase 5D

1

4

High-throughput

0.494

High

1410993

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

2

High-throughput

0.494

High

426566

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.493

High

1370084

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.486

High

1410998

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.486

High

993729

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.481

High

1131993

MVP
Major vault protein

1

1

High-throughput

0.481

High

1017667

PR20D
Proline-rich protein 20D

1

1

High-throughput

0.470

High

1389054

Q96EJ4
PLAC8 protein

1

1

High-throughput

0.470

High

1411001

X5DP44
RNA binding protein fox-1 homolog

1

3

High-throughput

0.457

High

1017738

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

1272025

ARMX2
Armadillo repeat-containing X-linked protein 2

1

4

High-throughput

0.439

High

1394298

TET5A
Terminal nucleotidyltransferase 5A

1

4

High-throughput

0.439

High

1410994

PLAC8
Placenta-specific gene 8 protein

1

1

High-throughput

0.439

High

1389361

RNF31
E3 ubiquitin-protein ligase RNF31

1

2

High-throughput

0.437

High

1411000

X5DP17
Major vault protein isoform H

1

1

High-throughput

0.417

High

1410987

TOLIP
Toll-interacting protein

5

0

High-throughput

0.374

High

1066008

VAC14
Protein VAC14 homolog

3

0

High-throughput

0.352

High

1359750

NEUR4
Sialidase-4

3

0

High-throughput

0.348

High

1363754

PSMF1
Proteasome inhibitor PI31 subunit

2

0

High-throughput

0.319

High

582356

ARSA
Arylsulfatase A

2

0

High-throughput

0.316

High

1186852

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1241237

CA094
Uncharacterized protein C1orf94

2

0

High-throughput

0.316

High

1244059

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.316

High

1332302

BOLL
Protein boule-like

2

0

High-throughput

0.316

High

1391401

KLD7B
Kelch domain-containing protein 7B

2

0

High-throughput

0.316

High

1410990

PRR34
Proline-rich protein 34

2

0

High-throughput

0.316

High

1410986

CHAC1
Glutathione-specific gamma-glutamylcyclotransferase 1

1

0

High-throughput

0.304

High

437470

CRBA1
Beta-crystallin A3 [Cleaved into: Beta-crystallin A3, isoform A1, Delta4 form; Beta-crystallin A3, isoform A1, Delta7 form; Beta-crystallin A3, isoform A1, Delta8 form]

1

0

High-throughput

0.299

High

337904

CLD7
Claudin-7

1

0

High-throughput

0.282

High

430639

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.282

High

1158035

SNPC1
snRNA-activating protein complex subunit 1

1

0

High-throughput

0.282

High

1328395

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.282

High

1360599

DEDD2
DNA-binding death effector domain-containing protein 2

1

0

High-throughput

0.282

High

1395003

RADIL
Ras-associating and dilute domain-containing protein

1

0

High-throughput

0.282

High

1410984

LZTS2
Leucine zipper putative tumor suppressor 2

1

0

High-throughput

0.282

High

270117

TMCC2
Transmembrane and coiled-coil domains protein 2

1

0

High-throughput

0.251

Low

1191396

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

1353130

FBF1
Fas-binding factor 1

1

0

High-throughput

0.251

Low

1310069

U2D2L
Putative ubiquitin-conjugating enzyme E2 D2-like protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025