Protein: HSFY1
Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like)

Gene: HSFY1
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q96LI6

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:1990837 - sequence-specific double-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

288315

GCM2
Chorion-specific transcription factor GCMb

6

0

High-throughput

0.710

High

351456

TBX6
T-box transcription factor TBX6

4

1

High-throughput

0.705

High

1397056

HSFY1
Heat shock transcription factor, Y-linked

1

17

High-throughput

0.691

High

1088510

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

3

High-throughput

0.628

High

1132900

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

3

High-throughput

0.628

High

297024

CCNK
Cyclin-K

2

1

High-throughput

0.606

High

927495

ATX1
Ataxin-1

2

2

High-throughput

0.606

High

1119597

NFYC
Nuclear transcription factor Y subunit gamma

2

1

High-throughput

0.606

High

1232979

OTU7B
OTU domain-containing protein 7B

2

1

High-throughput

0.606

High

1289273

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

3

High-throughput

0.606

High

1397057

TOX2
TOX high mobility group box family member 2

2

1

High-throughput

0.606

High

1397061

SATB2
DNA-binding protein SATB2

2

0

High-throughput

0.602

High

63013

POTEF
POTE ankyrin domain family member F

2

2

High-throughput

0.574

High

239984

SOX15
Transcription factor SOX-15

1

2

High-throughput

0.573

High

913007

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

2

High-throughput

0.573

High

169710

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.541

High

1332012

BANP
Protein BANP

1

1

High-throughput

0.541

High

1372034

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.536

High

1144864

RABE1
Rab GTPase-binding effector protein 1

1

2

High-throughput

0.536

High

253377

JAK2
Tyrosine-protein kinase JAK2

1

0

High-throughput

0.518

High

1086674

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.518

High

384715

CRYAB
Alpha-crystallin B chain

1

2

High-throughput

0.515

High

461819

HS90A
Heat shock protein HSP 90-alpha

1

10

High-throughput

0.515

High

593782

PECA1
Platelet endothelial cell adhesion molecule

1

2

High-throughput

0.515

High

728389

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.515

High

776997

PPM1A
Protein phosphatase 1A

1

0

High-throughput

0.513

High

933265

AIF1
Allograft inflammatory factor 1

1

0

High-throughput

0.513

High

1055957

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.513

High

1383620

E2F7
Transcription factor E2F7

1

0

High-throughput

0.513

High

1397058

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.513

High

1397060

RFOX1
RNA binding protein fox-1 homolog 1

1

5

High-throughput

0.494

High

474905

VIME
Vimentin

1

0

High-throughput

0.493

High

957649

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

0

High-throughput

0.493

High

85471

B7ZLP7
RNA-binding protein 47

1

1

High-throughput

0.470

High

75871

B4DE54
Protein BANP

1

1

High-throughput

0.457

High

48057

RBM47
RNA-binding protein 47

1

1

High-throughput

0.439

High

1397062

X5D7T5
RNA binding protein fox-1 homolog

1

4

High-throughput

0.417

High

1397063

X5DP44
RNA binding protein fox-1 homolog

1

4

High-throughput

0.417

High

702657

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

2

0

High-throughput

0.328

High

1397059

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.316

High

1180177

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.299

High

1271262

SV2B
Synaptic vesicle glycoprotein 2B

1

0

High-throughput

0.299

High

660291

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.268

Low

1139115

DAZP2
DAZ-associated protein 2

1

0

High-throughput

0.268

Low

1360727

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025