Protein: ILEU
Leukocyte elastase inhibitor (LEI) (Monocyte/neutrophil elastase inhibitor) (EI) (M/NEI) (Peptidase inhibitor 2) (PI-2) (Serpin B1)

Gene: ILEU, SERPINB1
Organism: Homo sapiens
Interactions: 57
UniProt ID: P30740

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005769 - early endosome
GO:0010951 - negative regulation of endopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

621770

PRTN3
Myeloblastin

2

20

Small-scale

0.799

High

445249

CEL3B
Chymotrypsin-like elastase family member 3B

1

12

High-throughput

0.691

High

439065

ELNE
Neutrophil elastase

1

20

Small-scale

0.647

High

675663

DD19B
ATP-dependent RNA helicase DDX19B

2

9

High-throughput

0.611

High

675627

SOX2
Transcription factor SOX-2

3

12

High-throughput

0.609

High

675652

FSD1
Fibronectin type III and SPRY domain-containing protein 1

3

12

High-throughput

0.609

High

675641

ZIC1
Zinc finger protein ZIC 1

2

7

High-throughput

0.574

High

675650

CDK15
Cyclin-dependent kinase 15

2

7

High-throughput

0.574

High

675659

TB22B
TBC1 domain family member 22B

2

7

High-throughput

0.574

High

565881

AATC
Aspartate aminotransferase, cytoplasmic

1

8

High-throughput

0.536

High

675632

T2R41
Taste receptor type 2 member 41

1

1

High-throughput

0.536

High

675640

STK11
Serine/threonine-protein kinase STK11

1

4

High-throughput

0.536

High

675647

FA24B
Protein FAM24B

1

1

High-throughput

0.536

High

226627

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.533

High

675638

KPCE
Protein kinase C epsilon type

2

5

High-throughput

0.521

High

675635

HTRA3
Serine protease HTRA3

1

0

High-throughput

0.513

High

675651

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.513

High

675633

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.501

High

239806

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.489

High

303657

OR2A4
Olfactory receptor 2A4

1

13

High-throughput

0.489

High

309371

MBD4
Methyl-CpG-binding domain protein 4

1

1

High-throughput

0.489

High

675630

STX17
Syntaxin-17

1

9

High-throughput

0.489

High

675631

DSCR6
Protein ripply3

1

7

High-throughput

0.489

High

675636

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

9

High-throughput

0.489

High

675645

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

1

High-throughput

0.489

High

675646

ELOA2
Elongin-A2

1

2

High-throughput

0.489

High

675653

SRRT
Serrate RNA effector molecule homolog

1

5

High-throughput

0.489

High

675656

COE2
Transcription factor COE2

1

5

High-throughput

0.489

High

675660

KLH11
Kelch-like protein 11

1

6

High-throughput

0.489

High

675662

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

3

High-throughput

0.489

High

373762

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

377126

GCR
Glucocorticoid receptor

1

9

High-throughput

0.479

High

503520

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

675629

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

675639

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

224321

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

675644

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

675642

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.445

High

552030

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

569258

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.437

High

650457

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

675626

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

675628

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.437

High

675634

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.437

High

675654

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

5

High-throughput

0.437

High

675655

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

675657

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.437

High

675658

FBX6
F-box only protein 6

1

7

High-throughput

0.437

High

675661

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.437

High

675664

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

162431

XPO1
Exportin-1

1

2

Small-scale

0.408

High

675643

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

2

High-throughput

0.407

High

675637

TF2B
Transcription initiation factor IIB

3

0

High-throughput

0.347

High

617730

NFYA
Nuclear transcription factor Y subunit alpha

2

0

High-throughput

0.328

High

433043

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.279

Low

675648

IQCF1
IQ domain-containing protein F1

1

0

High-throughput

0.279

Low

675649

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024