Protein: TRAM1
Translocating chain-associated membrane protein 1 (Protein TRAM1)

Gene: TRAM1
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q15629

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006613 - cotranslational protein targeting to membrane
GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0006986 - response to unfolded protein

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396182

ESR1
Estrogen receptor

4

3

Small-scale

0.682

High

820648

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.618

High

1150608

UN93B
Protein unc-93 homolog B1

2

2

High-throughput

0.601

High

903924

BAP31
B-cell receptor-associated protein 31

1

5

Small-scale

0.592

High

869596

SC6A8
Sodium- and chloride-dependent creatine transporter 1

2

13

Small-scale

0.571

High

1150603

ESR2
Estrogen receptor beta

2

3

Small-scale

0.554

High

1150611

SG196
Protein O-mannose kinase

1

4

High-throughput

0.536

High

1150595

S15A3
Solute carrier family 15 member 3

2

5

High-throughput

0.521

High

1150612

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

High-throughput

0.515

High

253842

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.513

High

1150604

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

230326

CREB3
Cyclic AMP-responsive element-binding protein 3

1

2

High-throughput

0.508

High

508021

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

572441

DRD2
D(2) dopamine receptor

1

9

High-throughput

0.494

High

422151

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

178275

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.479

High

979714

H4
Histone H4

1

1

High-throughput

0.479

High

1136639

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

1

High-throughput

0.479

High

1150590

MBOA1
Membrane-bound glycerophospholipid O-acyltransferase 1

1

1

High-throughput

0.479

High

1150597

RN149
E3 ubiquitin-protein ligase RNF149

1

1

Small-scale

0.479

High

1150600

SPP
Signal peptide peptidase

1

1

Small-scale

0.479

High

1150616

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.479

High

1150606

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

241773

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

409391

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

Small-scale

0.458

High

413899

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

766583

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

788927

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.458

High

939926

TPTE
Putative tyrosine-protein phosphatase TPTE

1

0

High-throughput

0.458

High

1027014

REEP5
Receptor expression-enhancing protein 5

1

0

Small-scale

0.458

High

1150605

FAF2
FAS-associated factor 2

1

0

High-throughput

0.458

High

1150607

DERL1
Derlin-1

1

0

Small-scale

0.458

High

104155

F5H1C8
Solute carrier family 15 member 3

1

5

High-throughput

0.445

High

256037

S19A2
Thiamine transporter 1

1

5

High-throughput

0.445

High

303232

S22A5
Organic cation/carnitine transporter 2

1

7

High-throughput

0.445

High

351222

MOT3
Monocarboxylate transporter 3

1

2

High-throughput

0.445

High

722464

CTR1
High affinity cationic amino acid transporter 1

1

8

High-throughput

0.445

High

870238

S6A12
Sodium- and chloride-dependent betaine transporter

1

13

High-throughput

0.445

High

870362

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

13

High-throughput

0.445

High

1139432

S39AE
Metal cation symporter ZIP14

1

8

High-throughput

0.445

High

1150587

MFSD5
Molybdate-anion transporter

1

3

High-throughput

0.445

High

1150592

S35E3
Solute carrier family 35 member E3

1

1

High-throughput

0.445

High

1150594

S35F2
Solute carrier family 35 member F2

1

7

High-throughput

0.445

High

1150609

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

13

High-throughput

0.445

High

218214

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

293739

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

830799

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

1150585

PKN2
Serine/threonine-protein kinase N2

1

3

High-throughput

0.437

High

1150588

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

1150591

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1150610

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1150614

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

1150615

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1150618

RNF11
RING finger protein 11

1

2

Small-scale

0.437

High

727562

SC6A4
Sodium-dependent serotonin transporter

1

13

High-throughput

0.407

High

1150586

S35F1
Solute carrier family 35 member F1

1

9

High-throughput

0.407

High

1150589

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

3

High-throughput

0.407

High

1150593

S22A9
Organic anion transporter 7

1

7

High-throughput

0.407

High

1150598

ZNT7
Zinc transporter 7

1

6

High-throughput

0.407

High

1150599

MFSD8
Major facilitator superfamily domain-containing protein 8

1

3

High-throughput

0.407

High

1150602

CTR3
Cationic amino acid transporter 3

1

8

High-throughput

0.407

High

1150613

S35C2
Solute carrier family 35 member C2

1

3

High-throughput

0.407

High

1150617

S22AE
Solute carrier family 22 member 14

1

7

High-throughput

0.407

High

1038216

GUC2A
Guanylin

2

0

High-throughput

0.316

High

129113

MEN1
Menin

1

0

High-throughput

0.249

Low

437185

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.249

Low

1150601

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

1150596

LAT4
Large neutral amino acids transporter small subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025