Protein: ERN2
Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (hIRE2p) (Ire1-beta) (IRE1b) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]

Gene: ERN2
Organism: Homo sapiens
Interactions: 21
UniProt ID: Q76MJ5

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004519 - endonuclease activity
GO:0004521 - RNA endonuclease activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

538287

ENPL
Endoplasmin

1

8

High-throughput

0.691

High

1028071

DNJC3
DnaJ homolog subfamily C member 3

1

6

High-throughput

0.691

High

1052545

RCN2
Reticulocalbin-2

1

20

High-throughput

0.691

High

1070845

RCN1
Reticulocalbin-1

1

8

High-throughput

0.691

High

1176314

DJB11
DnaJ homolog subfamily B member 11

1

2

High-throughput

0.691

High

1176310

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.553

High

164945

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.536

High

304226

UBR5
E3 ubiquitin-protein ligase UBR5

1

5

High-throughput

0.536

High

423275

PDIA1
Protein disulfide-isomerase

1

6

High-throughput

0.536

High

499864

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.536

High

531881

PDIA4
Protein disulfide-isomerase A4

1

6

High-throughput

0.536

High

737383

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.536

High

1049244

KEAP1
Kelch-like ECH-associated protein 1

1

2

High-throughput

0.536

High

1067745

PDIA6
Protein disulfide-isomerase A6

1

6

High-throughput

0.536

High

1176312

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.536

High

1176313

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

1

High-throughput

0.536

High

839623

SERPH
Serpin H1

1

0

High-throughput

0.513

High

1176311

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

451919

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

1

High-throughput

0.489

High

1058456

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.489

High

237667

SEP15
Selenoprotein F

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024