Protein: PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (EC 3.1.3.-) (EC 3.6.1.-) (EC 3.6.1.68) (Lipid phosphatase-related protein-B) (LPRP-B) (PA-PSP) (Phosphatidic acid phosphatase type 2 domain-containing protein 2) (PPAP2 domain-containing protein 2) (Phospholipid phosphatase 6) (Presqualene diphosphate phosphatase) (Type 1 polyisoprenoid diphosphate phosphatase)

Gene: PLPP6
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q8IY26

Gene Ontology (top 5):
GO:0005637 - nuclear inner membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006695 - cholesterol biosynthetic process
GO:0006720 - isoprenoid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

296246

AQP8
Aquaporin-8

2

1

High-throughput

0.606

High

315491

CLD9
Claudin-9

2

2

High-throughput

0.606

High

560476

PRLR
Prolactin receptor

2

1

High-throughput

0.606

High

1037631

AQP6
Aquaporin-6

2

1

High-throughput

0.606

High

1147804

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

2

High-throughput

0.606

High

1166207

LAYN
Layilin

2

1

High-throughput

0.606

High

1166506

BTNL9
Butyrophilin-like protein 9

2

1

High-throughput

0.606

High

1182896

BT2A1
Butyrophilin subfamily 2 member A1

2

1

High-throughput

0.606

High

1221942

RNF5
E3 ubiquitin-protein ligase RNF5

2

1

High-throughput

0.606

High

267242

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

2

0

High-throughput

0.580

High

516076

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

545137

PVR
Poliovirus receptor

2

0

High-throughput

0.580

High

554331

MUC1
Mucin-1

2

0

High-throughput

0.580

High

557191

PGFRA
Platelet-derived growth factor receptor alpha

2

0

High-throughput

0.580

High

602549

COMT
Catechol O-methyltransferase

2

0

High-throughput

0.580

High

1012189

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.580

High

1024631

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.580

High

1044751

I10R1
Interleukin-10 receptor subunit alpha

2

0

High-throughput

0.580

High

1059483

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

1068287

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1083949

STX1A
Syntaxin-1A

2

0

High-throughput

0.580

High

1109929

SHSL1
Protein shisa-like-1

2

0

High-throughput

0.580

High

1128643

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

1134240

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

0

High-throughput

0.580

High

1202315

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.580

High

1221921

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.580

High

1221924

S7A14
Solute carrier family 7 member 14

2

0

High-throughput

0.580

High

1221925

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.580

High

1221927

F174A
Membrane protein FAM174A

2

0

High-throughput

0.580

High

1221928

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

1221930

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

1221932

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.580

High

1221935

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.580

High

1221937

RN170
E3 ubiquitin-protein ligase RNF170

2

0

High-throughput

0.580

High

1221938

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.580

High

1221940

FIMP
Fertilization-influencing membrane protein

2

0

High-throughput

0.580

High

1221941

SIG12
Sialic acid-binding Ig-like lectin 12

2

0

High-throughput

0.580

High

1221943

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

1221944

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.580

High

1221945

CLC4M
C-type lectin domain family 4 member M

2

0

High-throughput

0.580

High

1221947

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

0

High-throughput

0.580

High

1221949

TR10D
Tumor necrosis factor receptor superfamily member 10D

2

0

High-throughput

0.580

High

1056214

I13R2
Interleukin-13 receptor subunit alpha-2

2

1

High-throughput

0.553

High

369965

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

1221934

Q96FX9
Claudin

1

2

High-throughput

0.515

High

172105

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.513

High

1221929

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.513

High

881964

CLD15
Claudin-15

1

2

High-throughput

0.481

High

1221923

TMIE
Transmembrane inner ear expressed protein

1

0

High-throughput

0.460

High

1041989

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1066370

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

529386

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

312728

CXB5
Gap junction beta-5 protein

2

0

High-throughput

0.316

High

1134977

GORAB
RAB6-interacting golgin

2

0

High-throughput

0.316

High

1203249

AMGO1
Amphoterin-induced protein 1

2

0

High-throughput

0.316

High

1221920

SYNE4
Nesprin-4

2

0

High-throughput

0.316

High

1221922

KASH5
Protein KASH5

2

0

High-throughput

0.316

High

1221926

SYNPR
Synaptoporin

2

0

High-throughput

0.316

High

1221939

PHAR3
Phosphatase and actin regulator 3

2

0

High-throughput

0.316

High

1221946

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

0

High-throughput

0.316

High

1221948

GKN1
Gastrokine-1

2

0

High-throughput

0.316

High

1221950

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.316

High

1221933

INT12
Integrator complex subunit 12

1

0

High-throughput

0.279

Low

1221931

SOCS4
Suppressor of cytokine signaling 4

1

0

High-throughput

0.251

Low

1221936

HSH2D
Hematopoietic SH2 domain-containing protein

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024