Protein: MCRS1
Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J) (MCRS2)

Gene: MCRS1
Organism: Homo sapiens
Interactions: 244
UniProt ID: Q96EZ8

Gene Ontology (top 5):
GO:0000123 - histone acetyltransferase complex
GO:0000723 - telomere maintenance
GO:0002151 - G-quadruplex RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1334352

IN80E
INO80 complex subunit E

9

2

Small-scale

0.749

High

154433

SH2B2
SH2B adapter protein 2

2

0

High-throughput

0.742

High

853838

MK09
Mitogen-activated protein kinase 9

2

0

High-throughput

0.742

High

1324653

AGGF1
Angiogenic factor with G patch and FHA domains 1

2

0

High-throughput

0.742

High

1390143

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

2

0

High-throughput

0.742

High

1390199

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

6

1

Small-scale

0.733

High

1104645

IKZF1
DNA-binding protein Ikaros

5

3

High-throughput

0.725

High

1390189

INO80
Chromatin-remodeling ATPase INO80

6

3

Small-scale

0.724

High

1390195

RUVB1
RuvB-like 1

5

1

Small-scale

0.712

High

965158

WDR5
WD repeat-containing protein 5

5

1

Small-scale

0.706

High

675624

TYY1
Transcriptional repressor protein YY1

4

1

High-throughput

0.699

High

1029726

FOXK2
Forkhead box protein K2

1

1

High-throughput

0.691

High

1390151

PHF20
PHD finger protein 20

4

5

High-throughput

0.691

High

1390193

RUVB2
RuvB-like 2

4

1

High-throughput

0.691

High

503643

TFPT
TCF3 fusion partner

5

0

Small-scale

0.676

High

182026

ZBT22
Zinc finger and BTB domain-containing protein 22

3

1

High-throughput

0.675

High

1390181

DAXX
Death domain-associated protein 6

4

0

Small-scale

0.675

High

1292612

GPBP1
Vasculin

3

1

High-throughput

0.671

High

1390197

WBP11
WW domain-binding protein 11

3

2

High-throughput

0.671

High

900086

FXR1
RNA-binding protein FXR1

3

1

High-throughput

0.667

High

900455

FXR2
RNA-binding protein FXR2

3

1

High-throughput

0.667

High

1276092

KANL1
KAT8 regulatory NSL complex subunit 1

3

2

High-throughput

0.667

High

279454

TULP3
Tubby-related protein 3

4

0

High-throughput

0.661

High

1390149

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

0

Small-scale

0.654

High

325979

UBR5
E3 ubiquitin-protein ligase UBR5

3

0

Small-scale

0.652

High

1143468

PCM1
Pericentriolar material 1 protein

4

0

High-throughput

0.652

High

1390177

KANL3
KAT8 regulatory NSL complex subunit 3

3

1

High-throughput

0.650

High

1154559

CC85B
Coiled-coil domain-containing protein 85B

3

0

Small-scale

0.643

High

943493

DSCR6
Protein ripply3

3

0

High-throughput

0.639

High

1390173

MED4
Mediator of RNA polymerase II transcription subunit 4

3

0

High-throughput

0.639

High

1390147

CSRN1
Cysteine/serine-rich nuclear protein 1

3

0

High-throughput

0.636

High

1200561

IN80D
INO80 complex subunit D

3

2

High-throughput

0.633

High

1242488

NFRKB
Nuclear factor related to kappa-B-binding protein

3

1

High-throughput

0.633

High

1388041

TRI44
Tripartite motif-containing protein 44

2

1

High-throughput

0.628

High

1390171

GPBL1
Vasculin-like protein 1

2

1

High-throughput

0.628

High

1244681

IN80C
INO80 complex subunit C

3

0

High-throughput

0.622

High

1390169

ARP5
Actin-related protein 5

3

0

High-throughput

0.622

High

323522

TRI37
E3 ubiquitin-protein ligase TRIM37

2

0

High-throughput

0.618

High

1330049

USBP1
Harmonin-binding protein USHBP1

3

1

High-throughput

0.616

High

71464

P20L1
PHD finger protein 20-like protein 1

2

2

High-throughput

0.611

High

1390168

ARP8
Actin-related protein 8

3

0

High-throughput

0.606

High

220792

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

2

1

High-throughput

0.606

High

249000

EVI5
Ecotropic viral integration site 5 protein homolog

2

1

High-throughput

0.606

High

255526

CYTIP
Cytohesin-interacting protein

2

2

High-throughput

0.606

High

258389

GAS7
Growth arrest-specific protein 7

2

1

High-throughput

0.606

High

332032

KAT7
Histone acetyltransferase KAT7

2

3

High-throughput

0.606

High

520621

RARA
Retinoic acid receptor alpha

2

3

High-throughput

0.606

High

848426

MAGA6
Melanoma-associated antigen 6

2

1

High-throughput

0.606

High

896431

ERF
ETS domain-containing transcription factor ERF

2

4

High-throughput

0.606

High

935595

MFAP1
Microfibrillar-associated protein 1

2

1

High-throughput

0.606

High

1208628

BRM1L
Breast cancer metastasis-suppressor 1-like protein

2

1

High-throughput

0.606

High

1228205

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

2

1

High-throughput

0.606

High

1238100

HMBX1
Homeobox-containing protein 1

2

1

High-throughput

0.606

High

1244025

ZCH12
Zinc finger CCHC domain-containing protein 12

2

1

High-throughput

0.606

High

1277271

MIER3
Mesoderm induction early response protein 3

2

2

High-throughput

0.606

High

1287248

TBCD1
TBC1 domain family member 1

2

1

High-throughput

0.606

High

1324706

MIER2
Mesoderm induction early response protein 2

2

2

High-throughput

0.606

High

1390144

PKNX2
Homeobox protein PKNOX2

2

1

High-throughput

0.606

High

1390154

BACH2
Transcription regulator protein BACH2

2

1

High-throughput

0.606

High

1390159

BRD8
Bromodomain-containing protein 8

2

1

High-throughput

0.606

High

1390162

IKZF4
Zinc finger protein Eos

2

3

High-throughput

0.606

High

1390172

BRMS1
Breast cancer metastasis-suppressor 1

2

1

High-throughput

0.606

High

1390183

ZN639
Zinc finger protein 639

2

1

High-throughput

0.606

High

1390184

IKZF3
Zinc finger protein Aiolos

2

3

High-throughput

0.606

High

622664

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

0

High-throughput

0.602

High

749799

CADH5
Cadherin-5

2

0

High-throughput

0.602

High

1012357

RT15
Small ribosomal subunit protein uS15m

2

0

High-throughput

0.602

High

1331720

NECA1
N-terminal EF-hand calcium-binding protein 1

2

0

High-throughput

0.602

High

1390185

PNMA2
Paraneoplastic antigen Ma2

2

1

High-throughput

0.601

High

1390140

MCRS1
Microspherule protein 1

1

0

High-throughput

0.589

High

997935

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.586

High

1235104

TTBK2
Tau-tubulin kinase 2

1

0

Small-scale

0.586

High

1364514

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

1

Small-scale

0.584

High

1390166

KAT8
Histone acetyltransferase KAT8

2

3

Small-scale

0.584

High

51477

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

0

High-throughput

0.580

High

67842

SRRM4
Serine/arginine repetitive matrix protein 4

2

0

High-throughput

0.580

High

155018

BHE40
Class E basic helix-loop-helix protein 40

2

0

High-throughput

0.580

High

299846

SNPC5
snRNA-activating protein complex subunit 5

2

0

High-throughput

0.580

High

346741

CAVN2
Caveolae-associated protein 2

2

0

High-throughput

0.580

High

600238

ZNF23
Zinc finger protein 23

2

0

High-throughput

0.580

High

601979

ZNF8
Zinc finger protein 8

2

0

High-throughput

0.580

High

800041

COIL
Coilin

2

0

High-throughput

0.580

High

833670

NAA10
N-alpha-acetyltransferase 10

2

0

High-throughput

0.580

High

893727

MEOX1
Homeobox protein MOX-1

2

0

High-throughput

0.580

High

908715

CCNH
Cyclin-H

2

0

High-throughput

0.580

High

933878

GEM
GTP-binding protein GEM

2

0

High-throughput

0.580

High

1022768

XIAP
E3 ubiquitin-protein ligase XIAP

2

0

High-throughput

0.580

High

1032032

TFAP4
Transcription factor AP-4

2

0

High-throughput

0.580

High

1036857

SP4
Transcription factor Sp4

2

0

High-throughput

0.580

High

1061814

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

1133356

NC2A
Dr1-associated corepressor

2

0

High-throughput

0.580

High

1137933

TNIP1
TNFAIP3-interacting protein 1

2

0

High-throughput

0.580

High

1152941

NAB2
NGFI-A-binding protein 2

2

0

High-throughput

0.580

High

1213133

BEND3
BEN domain-containing protein 3

2

0

High-throughput

0.580

High

1225040

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

0

High-throughput

0.580

High

1274014

BHA09
Class A basic helix-loop-helix protein 9

2

0

High-throughput

0.580

High

1287320

TAD2B
Transcriptional adapter 2-beta

2

0

High-throughput

0.580

High

1314933

CCD13
Coiled-coil domain-containing protein 13

2

0

High-throughput

0.580

High

1317038

FAM9A
Protein FAM9A

2

0

High-throughput

0.580

High

1349506

FNDC8
Fibronectin type III domain-containing protein 8

2

0

High-throughput

0.580

High

1350689

CCHCR
Coiled-coil alpha-helical rod protein 1

2

0

High-throughput

0.580

High

1357722

TRI41
E3 ubiquitin-protein ligase TRIM41

2

0

High-throughput

0.580

High

1383973

ARK2N
Protein ARK2N

2

0

High-throughput

0.580

High

1388829

HOOK2
Protein Hook homolog 2

2

0

High-throughput

0.580

High

1390141

CDA7L
Cell division cycle-associated 7-like protein

2

0

High-throughput

0.580

High

1390145

ASPP1
Apoptosis-stimulating of p53 protein 1

2

0

High-throughput

0.580

High

1390146

JKIP1
Janus kinase and microtubule-interacting protein 1

2

0

High-throughput

0.580

High

1390160

CARD9
Caspase recruitment domain-containing protein 9

2

0

High-throughput

0.580

High

1390161

TSYL2
Testis-specific Y-encoded-like protein 2

2

0

High-throughput

0.580

High

1390163

P63
Tumor protein 63

2

0

High-throughput

0.580

High

1390182

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.580

High

1390194

LZTS1
Leucine zipper putative tumor suppressor 1

2

0

High-throughput

0.580

High

1390196

AXIN2
Axin-2

2

0

High-throughput

0.580

High

396692

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

995192

CSK2B
Casein kinase II subunit beta

2

0

High-throughput

0.563

High

372822

MYC
Myc proto-oncogene protein

2

0

Small-scale

0.559

High

1312479

PHC2
Polyhomeotic-like protein 2

1

0

High-throughput

0.558

High

951806

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.554

High

1384675

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

Small-scale

0.549

High

355275

ACL6A
Actin-like protein 6A

2

0

High-throughput

0.547

High

1390157

IN80B
INO80 complex subunit B

2

0

High-throughput

0.547

High

159795

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.541

High

848922

MAGAB
Melanoma-associated antigen 11

1

1

High-throughput

0.541

High

162958

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.537

High

659554

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.536

High

320407

SASH1
SAM and SH3 domain-containing protein 1

1

0

Small-scale

0.529

High

799386

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.529

High

1286213

RALYL
RNA-binding Raly-like protein

1

0

High-throughput

0.518

High

1361894

TITIN
Titin

1

0

High-throughput

0.517

High

1212827

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

High-throughput

0.515

High

570550

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.515

High

185923

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.513

High

956976

CXCR4
C-X-C chemokine receptor type 4

1

0

High-throughput

0.513

High

1390180

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.513

High

1390187

INTU
Protein inturned

1

0

High-throughput

0.513

High

1390155

REN3B
Regulator of nonsense transcripts 3B

1

1

High-throughput

0.508

High

855167

NOP2
28S rRNA

1

0

Small-scale

0.504

High

531124

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

0

High-throughput

0.493

High

595552

H15
Histone H1.5

1

0

High-throughput

0.493

High

1372261

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.493

High

374845

RASH
GTPase HRas

1

0

High-throughput

0.493

High

442435

GELS
Gelsolin

1

0

High-throughput

0.493

High

843857

HD
Huntingtin

1

0

High-throughput

0.493

High

182719

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

249933

NPHN
Nephrin

1

1

High-throughput

0.489

High

162657

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.486

High

216511

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.486

High

246855

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

974336

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

0

High-throughput

0.486

High

538455

EGR2
E3 SUMO-protein ligase EGR2

1

1

High-throughput

0.481

High

1361129

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

384516

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

130573

SPT5H
Transcription elongation factor SPT5

1

1

Small-scale

0.479

High

156650

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

Small-scale

0.479

High

174388

ZN609
Zinc finger protein 609

1

2

High-throughput

0.479

High

175919

SET1A
Histone-lysine N-methyltransferase SETD1A

1

4

High-throughput

0.479

High

194599

KDM6A
Lysine-specific demethylase 6A

1

1

High-throughput

0.479

High

404319

GCR
Glucocorticoid receptor

1

5

High-throughput

0.479

High

464028

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

1

Small-scale

0.479

High

520280

ANDR
Androgen receptor

1

5

High-throughput

0.479

High

674288

BRD2
Bromodomain-containing protein 2

1

4

High-throughput

0.479

High

739018

ELF1
ETS-related transcription factor Elf-1

1

4

High-throughput

0.479

High

834024

HNF4A
Hepatocyte nuclear factor 4-alpha

1

3

High-throughput

0.479

High

837077

ELK3
ETS domain-containing protein Elk-3

1

4

High-throughput

0.479

High

905462

HCFC1
Host cell factor 1

1

1

High-throughput

0.479

High

928317

ATN1
Atrophin-1

1

1

High-throughput

0.479

High

1041580

KMT2A
Histone-lysine N-methyltransferase 2A

1

4

High-throughput

0.479

High

1045633

TF65
Transcription factor p65

1

1

High-throughput

0.479

High

1106369

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

High-throughput

0.479

High

1132887

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

Small-scale

0.479

High

1133599

NFIX
Nuclear factor 1 X-type

1

2

High-throughput

0.479

High

1141257

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.479

High

1145506

RBBP5
Retinoblastoma-binding protein 5

1

2

High-throughput

0.479

High

1152723

ELF2
ETS-related transcription factor Elf-2

1

2

High-throughput

0.479

High

1366998

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1368561

KAT6A
Histone acetyltransferase KAT6A

1

4

High-throughput

0.479

High

1390148

ELF4
ETS-related transcription factor Elf-4

1

4

High-throughput

0.479

High

1390167

CSR2B
Cysteine-rich protein 2-binding protein

1

1

High-throughput

0.479

High

1390170

KANL2
KAT8 regulatory NSL complex subunit 2

1

2

High-throughput

0.479

High

1390176

CXXC1
CXXC-type zinc finger protein 1

1

3

High-throughput

0.479

High

1390178

RERE
Arginine-glutamic acid dipeptide repeats protein

1

1

High-throughput

0.479

High

1390179

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

1

High-throughput

0.479

High

1390186

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

1390188

ZN608
Zinc finger protein 608

1

2

High-throughput

0.479

High

1390190

YETS2
YEATS domain-containing protein 2

1

1

High-throughput

0.479

High

1390191

KMT2B
Histone-lysine N-methyltransferase 2B

1

4

High-throughput

0.479

High

1390192

SET1B
Histone-lysine N-methyltransferase SETD1B

1

4

High-throughput

0.479

High

1390200

HCFC2
Host cell factor 2

1

1

High-throughput

0.479

High

650350

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.470

High

1194566

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

1390153

KRA24
Keratin-associated protein 2-4

1

2

High-throughput

0.470

High

892712

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

926397

BLM
RecQ-like DNA helicase BLM

1

0

Small-scale

0.460

High

70872

CENPX
Centromere protein X

1

0

Small-scale

0.458

High

129320

MEN1
Menin

1

0

High-throughput

0.458

High

173214

XPO1
Exportin-1

1

0

High-throughput

0.458

High

284863

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.458

High

604719

UBF1
Nucleolar transcription factor 1

1

0

Small-scale

0.458

High

941236

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

961799

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.458

High

980126

H4
Histone H4

1

0

High-throughput

0.458

High

993472

SPT4H
Transcription elongation factor SPT4

1

0

Small-scale

0.458

High

1005938

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

1224764

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.458

High

1315038

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.458

High

1390156

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

1390174

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

1390175

ITSN2
Intersectin-2

1

0

High-throughput

0.458

High

823903

PBX2
Pre-B-cell leukemia transcription factor 2

1

1

Small-scale

0.457

High

505369

KRA23
Keratin-associated protein 2-3

1

2

High-throughput

0.439

High

1390198

WASC3
WASH complex subunit 3

6

0

High-throughput

0.386

High

1348935

ZCH10
Zinc finger CCHC domain-containing protein 10

4

0

High-throughput

0.359

High

1390150

KXDL1
KxDL motif-containing protein 1

3

0

High-throughput

0.348

High

1390158

CEP44
Centrosomal protein of 44 kDa

3

0

High-throughput

0.348

High

275549

RTN2
Reticulon-2

3

0

High-throughput

0.347

High

1179835

INSY1
Inhibitory synaptic factor 1

3

0

High-throughput

0.346

High

1339389

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

1386131

GCC1
GRIP and coiled-coil domain-containing protein 1

2

0

High-throughput

0.323

High

70415

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

281390

GGYF1
GRB10-interacting GYF protein 1

2

0

High-throughput

0.316

High

619260

TNNI1
Troponin I, slow skeletal muscle

2

0

High-throughput

0.316

High

950366

KR107
Keratin-associated protein 10-7

2

0

High-throughput

0.316

High

1063513

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

1144861

RABE1
Rab GTPase-binding effector protein 1

2

0

High-throughput

0.316

High

1200584

CTSRT
Cation channel sperm-associated targeting subunit tau

2

0

High-throughput

0.316

High

1256715

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.316

High

1291449

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.316

High

1322773

CNTRB
Centrobin

2

0

High-throughput

0.316

High

1332418

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

1340305

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

1359300

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

1367971

KRT35
Keratin, type I cuticular Ha5

2

0

High-throughput

0.316

High

1390164

OSBL3
Oxysterol-binding protein-related protein 3

2

0

High-throughput

0.316

High

1331215

K1958
Uncharacterized protein KIAA1958

1

0

High-throughput

0.299

High

1390152

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.282

High

718447

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1390165

PKHG2
Pleckstrin homology domain-containing family G member 2

1

0

High-throughput

0.279

Low

1390201

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1193502

CH034
Uncharacterized protein C8orf34

1

0

High-throughput

0.251

Low

1337448

CG057
Uncharacterized protein C7orf57

1

0

High-throughput

0.251

Low

1390142

CC136
Coiled-coil domain-containing protein 136

1

0

High-throughput

0.251

Low

174178

PI51B
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

1

0

High-throughput

0.249

Low

947034

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025