Protein: TRI40
E3 ubiquitin ligase TRIM40 (EC 2.3.2.27) (Probable E3 NEDD8-protein ligase) (RING finger protein 35)

Gene: TRI40, TRIM40
Organism: Homo sapiens
Interactions: 13
UniProt ID: Q6P9F5

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0008385 - IkappaB kinase complex
GO:0030308 - negative regulation of cell growth
GO:0032088 - negative regulation of NF-kappaB transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

345080

RIGI
Antiviral innate immune response receptor RIG-I

1

18

Small-scale

0.561

High

1243368

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

16

Small-scale

0.561

High

422356

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

167916

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

20

Small-scale

0.479

High

177892

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

20

Small-scale

0.479

High

286381

DAB1
Disabled homolog 1

1

2

Small-scale

0.479

High

1243364

MAVS
Mitochondrial antiviral-signaling protein

1

7

Small-scale

0.479

High

1243365

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

13

Small-scale

0.479

High

1243366

PHB2
Prohibitin-2

1

7

High-throughput

0.479

High

1243367

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.479

High

1243369

KPCD2
Serine/threonine-protein kinase D2

1

7

High-throughput

0.479

High

1243370

NEMO
NF-kappa-B essential modulator

1

17

Small-scale

0.479

High

1126707

BECN1
Beclin-1

1

2

Small-scale

0.457

High


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Last updated: 11Aug2025