Protein: HMCES
Abasic site processing protein HMCES (EC 4.-.-.-) (Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein) (ES cell-specific 5hmC-binding protein) (Peptidase HMCES) (EC 3.4.-.-) (SRAP domain-containing protein 1)

Gene: HMCES
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q96FZ2

Gene Ontology (top 5):
GO:0003697 - single-stranded DNA binding
GO:0005657 - replication fork
GO:0006508 - proteolysis
GO:0006974 - DNA damage response
GO:0008233 - peptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

553425

RFA2
Replication protein A 32 kDa subunit

3

1

High-throughput

0.667

High

1026508

RFA4
Replication protein A 30 kDa subunit

3

1

High-throughput

0.667

High

504569

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.574

High

721146

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.513

High

861887

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.513

High

1251682

NEIL3
Endonuclease 8-like 3

1

0

High-throughput

0.513

High

871731

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.489

High

1291648

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.489

High

808223

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.480

High

942867

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.457

High

1253591

FBX25
F-box only protein 25

1

1

Small-scale

0.457

High

1281813

FBX32
F-box only protein 32

1

1

High-throughput

0.437

High

1291650

KLDC3
Kelch domain-containing protein 3

2

0

High-throughput

0.328

High

1291653

HPBP1
Hsp70-binding protein 1

2

0

High-throughput

0.328

High

395463

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.314

High

206408

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.279

Low

241350

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

0

High-throughput

0.279

Low

323960

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

380836

S100B
Protein S100-B

1

0

High-throughput

0.279

Low

391836

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.279

Low

612495

XPA
DNA repair protein complementing XP-A cells

1

0

High-throughput

0.279

Low

648578

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

885818

MTPN
Myotrophin

1

0

High-throughput

0.279

Low

935107

H31
Histone H3.1

1

0

High-throughput

0.279

Low

980995

EMX2
Homeobox protein EMX2

1

0

High-throughput

0.279

Low

1220376

SKA3
Spindle and kinetochore-associated protein 3

1

0

High-throughput

0.279

Low

1291649

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.279

Low

1291651

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.279

Low

1291652

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.279

Low

1291655

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

0

High-throughput

0.279

Low

1291647

FAH2A
Fumarylacetoacetate hydrolase domain-containing protein 2A

1

0

High-throughput

0.269

Low

370192

ESR1
Estrogen receptor

1

0

High-throughput

0.249

Low

379718

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.249

Low

668904

PML
Protein PML

1

0

High-throughput

0.249

Low

1288231

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.249

Low

1291654

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1255801

Q8TE30
RNA-directed DNA polymerase

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024