HitPredict - High confidence protein-protein interactions

Protein: MDM4
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)

Gene: MDM4
Organism: Mus musculus
Interactions: 7
UniProt ID: O35618

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002027 - regulation of heart rate
GO:0003170 - heart valve development
GO:0003181 - atrioventricular valve morphogenesis
GO:0003203 - endocardial cushion morphogenesis

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
205233	MDM2 E3 ubiquitin-protein ligase Mdm2	7	5	Small-scale	0.958	High
205232	P53 Cellular tumor antigen p53	5	10	Small-scale	0.919	High
205235	1433G 14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]	2	11	Small-scale	0.584	High
205238	SPAG6 Sperm-associated antigen 6	1	3	High-throughput	0.555	High
205234	CDN1A Cyclin-dependent kinase inhibitor 1	1	2	Small-scale	0.479	High
205236	UBP7 Ubiquitin carboxyl-terminal hydrolase 7	1	8	Small-scale	0.479	High
205237	KC1A Casein kinase I isoform alpha	1	5	Small-scale	0.437	High

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Last updated: 11Aug2025