Protein: GROA
Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)]

Gene: GROA, CXCL1
Organism: Homo sapiens
Interactions: 30
UniProt ID: P09341

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006935 - chemotaxis
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

448988

CXCR2
C-X-C chemokine receptor type 2

9

20

Small-scale

0.957

High

448990

CXCL5
C-X-C motif chemokine 5

1

17

High-throughput

0.692

High

448992

CCL11
Eotaxin

1

20

High-throughput

0.692

High

448995

CXCL6
C-X-C motif chemokine 6

1

17

High-throughput

0.692

High

448983

GROA
Growth-regulated alpha protein

1

17

Small-scale

0.691

High

448985

CXCL2
C-X-C motif chemokine 2

1

18

High-throughput

0.691

High

448986

CXCL3
C-X-C motif chemokine 3

1

18

High-throughput

0.691

High

449000

ACKR1
Atypical chemokine receptor 1

4

20

Small-scale

0.686

High

353370

PIGR
Polymeric immunoglobulin receptor

1

2

Small-scale

0.618

High

448987

CXCR1
C-X-C chemokine receptor type 1

1

20

Small-scale

0.618

High

448997

TF65
Transcription factor p65

2

15

Small-scale

0.584

High

368849

ESR1
Estrogen receptor

1

2

High-throughput

0.541

High

448998

TRAF2
TNF receptor-associated factor 2

1

1

High-throughput

0.536

High

449007

TBK1
Serine/threonine-protein kinase TBK1

1

2

High-throughput

0.536

High

349076

RASH
GTPase HRas

1

0

High-throughput

0.518

High

448993

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.518

High

448989

MMP12
Macrophage metalloelastase

1

20

Small-scale

0.501

High

448996

XIAP
E3 ubiquitin-protein ligase XIAP

1

4

High-throughput

0.489

High

448999

BIRC2
Baculoviral IAP repeat-containing protein 2

1

4

High-throughput

0.489

High

449005

BIRC6
Baculoviral IAP repeat-containing protein 6

1

5

High-throughput

0.489

High

449001

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.470

High

448991

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.439

High

449004

HIPK2
Homeodomain-interacting protein kinase 2

1

0

Small-scale

0.292

High

207004

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.282

High

449003

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.279

Low

449006

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.279

Low

449002

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.269

Low

448984

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.249

Low

448994

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024