Protein: CISH
Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS)

Gene: CISH
Organism: Mus musculus
Interactions: 13
UniProt ID: Q62225

Gene Ontology (top 5):
GO:0001960 - negative regulation of cytokine-mediated signaling pathway
GO:0005886 - plasma membrane
GO:0016567 - protein ubiquitination
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

205446

SOCS2
Suppressor of cytokine signaling 2

2

18

Small-scale

0.786

High

575633

EPOR
Erythropoietin receptor

2

20

Small-scale

0.776

High

1034938

KPCT
Protein kinase C theta type

2

20

Small-scale

0.776

High

1223902

CUL5
Cullin-5

2

20

Small-scale

0.768

High

871461

LEPR
Leptin receptor

2

20

Small-scale

0.763

High

362447

ABL1
Tyrosine-protein kinase ABL1

1

19

Small-scale

0.724

High

998178

KPCB
Protein kinase C beta type

1

20

Small-scale

0.665

High

838410

STA5A
Signal transducer and activator of transcription 5A

2

20

Small-scale

0.665

High

632516

KPCA
Protein kinase C alpha type

1

20

Small-scale

0.618

High

689978

IL3B2
Interleukin-3 receptor class 2 subunit beta

1

20

Small-scale

0.479

High

236684

B2L11
Bcl-2-like protein 11

1

1

Small-scale

0.437

High

466741

EGR2
E3 SUMO-protein ligase EGR2

1

5

Small-scale

0.437

High

689980

IL3RB
Cytokine receptor common subunit beta

1

20

Small-scale

0.437

High


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Last updated: 11Aug2025