Protein: 3BHS2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II) (3-beta-HSD II) (3-beta-HSD adrenal and gonadal type) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)]

Gene: 3BHS2, HSD3B2
Organism: Homo sapiens
Interactions: 21
UniProt ID: P26439

Gene Ontology (top 5):
GO:0003854 - 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity
GO:0004769 - steroid delta-isomerase activity
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

534424

3BHS1
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

2

12

High-throughput

0.811

High

260759

H2AY
Core histone macro-H2A.1

2

2

High-throughput

0.628

High

508830

TOP2A
DNA topoisomerase 2-alpha

2

1

High-throughput

0.628

High

513532

PYC
Pyruvate carboxylase, mitochondrial

2

2

High-throughput

0.628

High

642827

TOP2B
DNA topoisomerase 2-beta

2

1

High-throughput

0.628

High

642828

TBL3
Transducin beta-like protein 3

2

2

High-throughput

0.628

High

213800

SYNC
Asparagine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.602

High

642836

CATF
Cathepsin F

2

0

High-throughput

0.602

High

470275

H2A1
Histone H2A type 1

2

1

High-throughput

0.574

High

642835

TM38A
Trimeric intracellular cation channel type A

2

1

High-throughput

0.574

High

642834

VRK1
Serine/threonine-protein kinase VRK1

1

3

High-throughput

0.536

High

307325

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.513

High

612959

TCEA1
Transcription elongation factor A protein 1

1

0

High-throughput

0.513

High

642837

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.513

High

642829

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.493

High

642833

WDR36
WD repeat-containing protein 36

1

4

High-throughput

0.489

High

642832

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.470

High

594710

ATP4A
Potassium-transporting ATPase alpha chain 1

1

4

Small-scale

0.437

High

642826

MTHR
Methylenetetrahydrofolate reductase

2

0

High-throughput

0.328

High

642830

H37
Histone H3-7

2

0

High-throughput

0.288

High

642831

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024