HitPredict

Interactor 1: HLAE (P13747)
HLA class I histocompatibility antigen, alpha chain E (MHC class I antigen E) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain E (sHLA-E)]
Gene: HLA-E

Interactor 2: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 9605335, 9660937
Identification Methods x-ray crystallography
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I
Common GO terms GO:0000139 - Golgi membrane
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 358
Hs

1 119
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024