Protein: MSHR
Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)

Gene: MSHR, MC1R
Organism: Homo sapiens
Interactions: 13
UniProt ID: Q01726

Gene Ontology (top 5):
GO:0004977 - melanocortin receptor activity
GO:0004980 - melanocyte-stimulating hormone receptor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1032114

OPN3
Opsin-3

1

18

Small-scale

0.665

High

377055

COLI
Pro-opiomelanocortin

1

3

Small-scale

0.647

High

244460

MGRN1
E3 ubiquitin-protein ligase MGRN1

3

2

Small-scale

0.640

High

732549

ARRB2
Beta-arrestin-2

1

9

Small-scale

0.618

High

882456

ARRB1
Beta-arrestin-1

1

9

Small-scale

0.618

High

1032111

MRAP
Melanocortin-2 receptor accessory protein

1

9

Small-scale

0.618

High

1032112

MRAP2
Melanocortin-2 receptor accessory protein 2

1

4

Small-scale

0.618

High

563636

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.536

High

473922

NFIC
Nuclear factor 1 C-type

1

0

High-throughput

0.479

High

580615

AMPN
Aminopeptidase N

1

3

High-throughput

0.479

High

767171

MERL
Merlin

1

5

High-throughput

0.479

High

1032113

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

8

Small-scale

0.479

High

1032115

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High


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Last updated: 11Aug2025