Protein: PKHG5
Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX)

Gene: PKHG5, Plekhg5
Organism: Mus musculus
Interactions: 14
UniProt ID: Q66T02

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0030027 - lamellipodium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1226825

PALS1
Protein PALS1

1

15

Small-scale

0.681

High

1226826

RHOA
Transforming protein RhoA

1

20

Small-scale

0.647

High

770654

RAB19
Ras-related protein Rab-19

1

3

High-throughput

0.575

High

1226828

GIPC1
PDZ domain-containing protein GIPC1

2

5

Small-scale

0.563

High

1226822

MPDZ
Multiple PDZ domain protein

1

20

Small-scale

0.481

High

1224963

INADL
InaD-like protein

1

20

Small-scale

0.481

High

1226821

AMOL2
Angiomotin-like protein 2

1

10

Small-scale

0.479

High

1226824

AMOL1
Angiomotin-like protein 1

1

15

Small-scale

0.479

High

1226829

V9GX76
Unconventional myosin-VI

1

9

Small-scale

0.479

High

1226820

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

16

High-throughput

0.437

High

313199

LIN7C
Protein lin-7 homolog C

1

20

Small-scale

0.408

High

993100

ACTG
Actin, cytoplasmic 2

1

14

Small-scale

0.408

High

1226823

AMOT
Angiomotin

1

20

Small-scale

0.408

High

1226827

MYO1C
Unconventional myosin-Ic

1

4

Small-scale

0.408

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025