Interactor 1: PKHG5 (Q66T02)
Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX)
Gene: Plekhg5
Interactor 2: RHOA (Q9QUI0)
Transforming protein RhoA (EC 3.6.5.2)
Gene: RHOA
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16467373 |
| Identification Methods | fluorescent resonance energy transfer |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ras~RhoGEF, Ras~SOS1_NGEF_PH |
| Common GO terms | GO:0005886 - plasma membrane GO:0030027 - lamellipodium GO:0043542 - endothelial cell migration |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
