Protein: NOP6
Nucleolar protein 6

Gene: NOP6
Organism: Saccharomyces cerevisiae S288C
Interactions: 143
UniProt ID: Q07623

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0019843 - rRNA binding
GO:0030490 - maturation of SSU-rRNA
GO:0030515 - snoRNA binding
GO:0030686 - 90S preribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

792600

UTP10
U3 small nucleolar RNA-associated protein 10

5

0

High-throughput

0.684

High

634792

KRR1
KRR1 small subunit processome component

4

0

High-throughput

0.664

High

982891

RRP5
rRNA biogenesis protein RRP5

4

0

High-throughput

0.664

High

655906

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

4

0

Small-scale

0.657

High

715993

UTP20
U3 small nucleolar RNA-associated protein 20

3

0

High-throughput

0.638

High

691433

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

3

0

High-throughput

0.638

High

733949

RPF2
Ribosome biogenesis protein RPF2

3

0

High-throughput

0.634

High

704435

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

3

0

High-throughput

0.628

High

979047

DHR1
Probable ATP-dependent RNA helicase DHR1

3

0

High-throughput

0.628

High

988643

UTP4
U3 small nucleolar RNA-associated protein 4

2

1

High-throughput

0.611

High

991545

BMS1
Ribosome biogenesis protein BMS1

2

1

High-throughput

0.611

High

624184

DBP2
ATP-dependent RNA helicase DBP2

2

0

High-throughput

0.588

High

635656

PWP2
Periodic tryptophan protein 2

2

0

High-throughput

0.585

High

645680

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.585

High

991540

RCL1
RNA 3'-terminal phosphate cyclase-like protein

2

0

High-throughput

0.585

High

991550

NOP58
Nucleolar protein 58

2

0

High-throughput

0.585

High

480912

RS8A
Small ribosomal subunit protein eS8A

2

0

High-throughput

0.559

High

748719

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

991548

YRA1
RNA annealing protein YRA1

2

1

High-throughput

0.558

High

865625

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.541

High

548453

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

2

High-throughput

0.536

High

699735

DRS1
ATP-dependent RNA helicase DRS1

1

2

High-throughput

0.536

High

733165

DBP7
ATP-dependent RNA helicase DBP7

1

3

High-throughput

0.536

High

976872

HAS1
ATP-dependent RNA helicase HAS1

1

4

High-throughput

0.536

High

991190

TSR1
Ribosome biogenesis protein TSR1

1

1

High-throughput

0.536

High

597908

PWP1
Periodic tryptophan protein 1

1

0

High-throughput

0.513

High

710931

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.513

High

754202

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.513

High

764255

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.513

High

765989

DPO5
rDNA transcriptional regulator POL5

1

0

High-throughput

0.513

High

766713

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.513

High

778869

NOP2
25S rRNA

1

0

High-throughput

0.513

High

791284

KRI1
Protein KRI1

1

0

High-throughput

0.513

High

811804

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.513

High

816915

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.513

High

816947

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.513

High

859441

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.513

High

860893

PESC
Pescadillo homolog

1

0

High-throughput

0.513

High

866066

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

978133

HMO1
High mobility group protein 1

1

0

High-throughput

0.513

High

979458

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.513

High

980164

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.513

High

991541

NOP12
Nucleolar protein 12

1

0

High-throughput

0.513

High

991546

YTM1
Ribosome biogenesis protein YTM1

1

0

High-throughput

0.513

High

991551

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

991552

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.513

High

485596

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.500

High

355669

H2B1
Histone H2B.1

1

1

High-throughput

0.489

High

356030

H2B2
Histone H2B.2

1

1

High-throughput

0.489

High

485842

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.489

High

633995

GBP2
Serine/arginine

1

1

High-throughput

0.489

High

837367

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.489

High

965050

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.489

High

965500

NOP3
Serine/arginine

1

2

High-throughput

0.489

High

638873

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.479

High

700652

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

804859

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.479

High

972641

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

985821

UTP21
U3 small nucleolar RNA-associated protein 21

1

1

Small-scale

0.479

High

987664

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

991549

MAK21
Ribosome biogenesis protein MAK21

1

1

High-throughput

0.479

High

141547

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383376

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

407352

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408150

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413732

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

479832

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

480341

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

481430

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.458

High

481561

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.458

High

482483

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

632116

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

635163

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

706516

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

820200

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

975845

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

979727

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

991553

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

991554

RL11B
Large ribosomal subunit protein uL5B

1

0

High-throughput

0.458

High

605169

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.457

High

762885

IMDH1
Putative inosine-5'-monophosphate dehydrogenase 1

1

1

High-throughput

0.457

High

960020

SEN1
Helicase SEN1

1

1

Small-scale

0.445

High

675783

RENT1
ATP-dependent helicase NAM7

1

1

Small-scale

0.437

High

731718

SDS22
Protein phosphatase 1 regulatory subunit SDS22

2

0

Small-scale

0.322

High

376946

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

0

Small-scale

0.310

High

548623

IDI1
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.282

High

371027

CBP2
Cytochrome B pre-mRNA-processing protein 2

1

0

High-throughput

0.279

Low

424927

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.279

Low

556329

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.279

Low

604720

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.279

Low

693239

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

High-throughput

0.279

Low

696709

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.279

Low

697859

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.279

Low

755463

TRA1
Transcription-associated protein 1

1

0

High-throughput

0.279

Low

765078

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.279

Low

809640

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.279

Low

859776

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.279

Low

972920

IMA1
Importin subunit alpha

1

0

High-throughput

0.279

Low

975545

RLI1
Translation initiation factor RLI1

1

0

High-throughput

0.279

Low

986144

IMB1
Importin subunit beta-1

1

0

High-throughput

0.279

Low

991539

ISA1
Iron-sulfur assembly protein 1

1

0

High-throughput

0.279

Low

797909

RRT5
Regulator of rDNA transcription protein 5

1

0

High-throughput

0.265

Low

643050

BUB3
Cell cycle arrest protein BUB3

1

0

Small-scale

0.261

Low

421701

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.261

Low

521064

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

634199

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.261

Low

357572

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.249

Low

358284

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

405854

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

408479

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

419506

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.249

Low

471281

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472418

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

478997

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

479183

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

524459

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

535133

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

558285

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

604626

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.249

Low

663467

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

665080

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

688453

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

698958

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.249

Low

730144

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

731616

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

743021

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.249

Low

752696

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

762604

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

775097

RL34B
Large ribosomal subunit protein eL34B

1

0

High-throughput

0.249

Low

860396

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

967788

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

984561

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

Small-scale

0.249

Low

986256

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

991542

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

991543

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

991544

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.249

Low

991547

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

866167

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.238

Low

340294

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

368442

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

424740

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

540167

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

681036

HS104
Heat shock protein 104

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024