Protein: ISW2
ISWI chromatin-remodeling complex ATPase ISW2 (EC 3.6.4.-) (Imitation switch protein 2)

Gene: ISW2
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: Q08773

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000183 - rDNA heterochromatin formation
GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

744923

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

3

17

Small-scale

0.855

High

902117

H3
Histone H3

3

20

Small-scale

0.817

High

697449

CHD1
Chromo domain-containing protein 1

2

17

High-throughput

0.802

High

355679

H2B1
Histone H2B.1

2

20

High-throughput

0.776

High

356040

H2B2
Histone H2B.2

2

20

High-throughput

0.759

High

859360

ITC1
Imitation switch two complex protein 1

12

17

Small-scale

0.756

High

979818

DPB4
DNA polymerase epsilon subunit D

9

4

Small-scale

0.749

High

356774

H4
Histone H4

2

16

High-throughput

0.737

High

392595

H2A2
Histone H2A.2

2

20

High-throughput

0.737

High

772756

DLS1
Protein DLS1

9

0

Small-scale

0.715

High

976405

NHP10
Non-histone protein 10

2

20

High-throughput

0.621

High

558301

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.618

High

687760

BTAF1
TATA-binding protein-associated factor MOT1

1

18

Small-scale

0.618

High

514275

NHP6B
Non-histone chromosomal protein 6B

2

20

High-throughput

0.588

High

822708

RFX1
RFX-like DNA-binding protein RFX1

2

7

High-throughput

0.588

High

607354

RFA1
Replication factor A protein 1

2

11

Small-scale

0.584

High

603344

SNF2
Transcription regulatory protein SNF2

1

16

Small-scale

0.575

High

996423

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

16

Small-scale

0.575

High

996427

H2AZ
Histone H2A.Z

1

20

High-throughput

0.575

High

705758

HSP78
Heat shock protein 78, mitochondrial

2

4

High-throughput

0.571

High

758983

UME6
Transcriptional regulatory protein UME6

1

0

Small-scale

0.537

High

333937

ADH1
Alcohol dehydrogenase 1

2

1

High-throughput

0.537

High

452131

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

1

High-throughput

0.536

High

513035

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.536

High

605391

HSP74
Heat shock protein SSA4

1

20

High-throughput

0.536

High

986149

IMB1
Importin subunit beta-1

1

3

High-throughput

0.536

High

986413

YL455
PWWP domain-containing protein YLR455W

1

10

Small-scale

0.536

High

996425

IES3
Ino eighty subunit 3

1

0

High-throughput

0.513

High

636768

CDC48
Cell division control protein 48

1

2

High-throughput

0.500

High

589038

PYRC
Dihydroorotase

1

1

High-throughput

0.479

High

601775

RCC1
Guanine nucleotide exchange factor SRM1

1

2

Small-scale

0.479

High

663552

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

688472

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

698968

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

12

High-throughput

0.479

High

716373

SPT10
Protein SPT10

1

4

High-throughput

0.479

High

775886

DSN1
Kinetochore-associated protein DSN1

1

4

High-throughput

0.479

High

978344

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.479

High

979182

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.479

High

986269

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

996424

SCC1
Sister chromatid cohesion protein 1

1

7

High-throughput

0.479

High

549635

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

978594

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.458

High

367030

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.445

High

419401

HAP2
Transcriptional activator HAP2

1

5

High-throughput

0.445

High

450221

HSP73
Heat shock protein SSA3

1

20

High-throughput

0.445

High

478583

HSP77
Import motor subunit, mitochondrial

1

17

High-throughput

0.445

High

495184

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

514218

NHP6A
Non-histone chromosomal protein 6A

1

20

High-throughput

0.445

High

515092

MCM1
Pheromone receptor transcription factor

1

9

High-throughput

0.445

High

516329

RAP1
DNA-binding protein RAP1

1

2

High-throughput

0.445

High

535776

ABF1
ARS-binding factor 1

1

1

High-throughput

0.445

High

609152

SIN3
Transcriptional regulatory protein SIN3

1

16

High-throughput

0.445

High

628905

SWI4
Regulatory protein SWI4

1

11

High-throughput

0.445

High

681055

HS104
Heat shock protein 104

1

4

High-throughput

0.445

High

689978

ASF1
Histone chaperone ASF1

1

10

High-throughput

0.445

High

690860

HIR1
Protein HIR1

1

20

High-throughput

0.445

High

695702

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

696088

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

705912

IXR1
Intrastrand cross-link recognition protein

1

20

High-throughput

0.445

High

707002

MSN2
Zinc finger protein MSN2

1

13

High-throughput

0.445

High

733318

SET3
SET domain-containing protein 3

1

18

High-throughput

0.445

High

754777

SSZ1
Ribosome-associated complex subunit SSZ1

1

15

High-throughput

0.445

High

766255

HSP7E
Heat shock protein SSC3, mitochondrial

1

17

High-throughput

0.445

High

769685

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

770114

RT106
Histone chaperone RTT106

1

3

High-throughput

0.445

High

772351

ATAD2
ATPase histone chaperone YTA7

1

6

High-throughput

0.445

High

805250

TAF1
Transcription initiation factor TFIID subunit 1

1

4

High-throughput

0.445

High

866529

APJ1
J domain-containing protein APJ1

1

9

High-throughput

0.445

High

969433

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

20

High-throughput

0.445

High

977710

GIS1
Transcriptional activator/repressor GIS1

1

9

High-throughput

0.445

High

981160

RCO1
Transcriptional regulatory protein RCO1

1

20

High-throughput

0.445

High

996426

RLF2
Chromatin assembly factor 1 subunit p90

1

13

High-throughput

0.445

High

768282

SCC4
MAU2 chromatid cohesion factor homolog

1

4

Small-scale

0.437

High

988601

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

5

High-throughput

0.407

High

336268

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

743794

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

744344

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

784557

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.249

Low

979543

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024