Protein: JAGN1
Protein jagunal homolog 1

Gene: JAGN1
Organism: Homo sapiens
Interactions: 158
UniProt ID: Q8N5M9

Gene Ontology (top 5):
GO:0002446 - neutrophil mediated immunity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006887 - exocytosis
GO:0007029 - endoplasmic reticulum organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160302

GOSR2
Golgi SNAP receptor complex member 2

2

1

High-throughput

0.606

High

179970

BET1
BET1 homolog

2

1

High-throughput

0.606

High

333095

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

1

High-throughput

0.606

High

989357

VAMP2
Vesicle-associated membrane protein 2

2

1

High-throughput

0.606

High

1097833

STX5
Syntaxin-5

2

3

High-throughput

0.606

High

1159602

STX1A
Syntaxin-1A

2

2

High-throughput

0.606

High

1279329

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

2

High-throughput

0.606

High

1328171

GIMA1
GTPase IMAP family member 1

2

1

High-throughput

0.606

High

1328205

SAR1A
Small COPII coat GTPase SAR1A

2

2

High-throughput

0.606

High

1328206

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

1

High-throughput

0.606

High

1328214

TECR
Very-long-chain enoyl-CoA reductase

2

1

High-throughput

0.606

High

1328217

VAPA
Vesicle-associated membrane protein-associated protein A

2

1

High-throughput

0.606

High

1328220

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

1

High-throughput

0.606

High

1328225

STX8
Syntaxin-8

2

1

High-throughput

0.606

High

422590

A4
Amyloid-beta precursor protein

2

0

High-throughput

0.592

High

144453

SCD
Stearoyl-CoA desaturase

2

0

High-throughput

0.580

High

162235

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.580

High

224448

PLPP2
Phospholipid phosphatase 2

2

0

High-throughput

0.580

High

254298

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

2

0

High-throughput

0.580

High

280260

SC22B
Vesicle-trafficking protein SEC22b

2

0

High-throughput

0.580

High

483931

HMOX1
Heme oxygenase 1

2

0

High-throughput

0.580

High

789927

FDFT
Squalene synthase

2

0

High-throughput

0.580

High

800303

INGR2
Interferon gamma receptor 2

2

0

High-throughput

0.580

High

937174

GP2
Pancreatic secretory granule membrane major glycoprotein GP2

2

0

High-throughput

0.580

High

1005399

CP4F2
Cytochrome P450 4F2

2

0

High-throughput

0.580

High

1067220

KCNA1
Potassium voltage-gated channel subfamily A member 1

2

0

High-throughput

0.580

High

1091946

SEC20
Vesicle transport protein SEC20

2

0

High-throughput

0.580

High

1092062

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

2

0

High-throughput

0.580

High

1125542

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

0

High-throughput

0.580

High

1142881

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1291422

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.580

High

1327020

VMA12
Vacuolar ATPase assembly protein VMA12

2

0

High-throughput

0.580

High

1328169

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

2

0

High-throughput

0.580

High

1328187

CGRF1
Cell growth regulator with RING finger domain protein 1

2

0

High-throughput

0.580

High

1328188

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.580

High

1328193

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

1328196

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.580

High

1328202

CERS4
Ceramide synthase 4

2

0

High-throughput

0.580

High

1328207

TREX1
Three-prime repair exonuclease 1

2

0

High-throughput

0.580

High

1328208

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

0

High-throughput

0.580

High

1328211

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

1328215

USE1
Vesicle transport protein USE1

2

0

High-throughput

0.580

High

1328224

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.580

High

1328228

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

1328229

UB2J1
Ubiquitin-conjugating enzyme E2 J1

2

0

High-throughput

0.580

High

1328230

FIS1
Mitochondrial fission 1 protein

2

0

High-throughput

0.580

High

1328231

IR3IP
Immediate early response 3-interacting protein 1

2

0

High-throughput

0.580

High

1328234

SERP1
Stress-associated endoplasmic reticulum protein 1

2

0

High-throughput

0.580

High

189708

STX7
Syntaxin-7

2

4

High-throughput

0.553

High

328698

VAMP5
Vesicle-associated membrane protein 5

2

1

High-throughput

0.553

High

553363

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

2

High-throughput

0.553

High

850839

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

3

High-throughput

0.553

High

1100689

STX3
Syntaxin-3

2

2

High-throughput

0.553

High

1177834

CL12B
C-type lectin domain family 12 member B

2

2

High-throughput

0.553

High

1187496

AR13B
ADP-ribosylation factor-like protein 13B

2

3

High-throughput

0.553

High

1328160

KI3L3
Killer cell immunoglobulin-like receptor 3DL3

2

3

High-throughput

0.553

High

1328166

STML3
Stomatin-like protein 3

2

1

High-throughput

0.553

High

1328172

CLC4D
C-type lectin domain family 4 member D

2

1

High-throughput

0.553

High

1328180

GIMA5
GTPase IMAP family member 5

2

1

High-throughput

0.553

High

1328182

FCRL2
Fc receptor-like protein 2

2

2

High-throughput

0.553

High

1328185

FCRL4
Fc receptor-like protein 4

2

2

High-throughput

0.553

High

1328227

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

1

High-throughput

0.553

High

1328226

S12A4
Solute carrier family 12 member 4

2

3

High-throughput

0.549

High

1328176

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

1

0

High-throughput

0.549

High

1328195

CLC7A
C-type lectin domain family 7 member A

1

2

High-throughput

0.523

High

1328223

S12A6
Solute carrier family 12 member 6

2

3

Small-scale

0.521

High

48196

A0AVG3
t-SNARE domain containing 1

1

4

High-throughput

0.515

High

698882

CALX
Calnexin

1

0

High-throughput

0.513

High

888920

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

1328175

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1328158

JAGN1
Protein jagunal homolog 1

1

0

High-throughput

0.460

High

1328189

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

417580

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

1249019

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

779714

MOT8
Monocarboxylate transporter 8

1

2

High-throughput

0.439

High

1328184

TSNA1
t-SNARE domain-containing protein 1

1

5

High-throughput

0.439

High

900923

RAB5C
Ras-related protein Rab-5C

1

1

High-throughput

0.437

High

1238738

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1328181

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1328201

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

943991

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

1328200

S12A5
Solute carrier family 12 member 5

1

3

High-throughput

0.407

High

1328233

S12A7
Solute carrier family 12 member 7

1

3

High-throughput

0.407

High

1328159

KASH5
Protein KASH5

3

0

High-throughput

0.352

High

49669

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

58673

FRMD3
FERM domain-containing protein 3

2

0

High-throughput

0.316

High

74179

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.316

High

168105

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

2

0

High-throughput

0.316

High

220181

TNF14
Tumor necrosis factor ligand superfamily member 14

2

0

High-throughput

0.316

High

258650

G37L1
G-protein coupled receptor 37-like 1

2

0

High-throughput

0.316

High

335255

CXB5
Gap junction beta-5 protein

2

0

High-throughput

0.316

High

335565

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.316

High

337118

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.316

High

337894

CLD7
Claudin-7

2

0

High-throughput

0.316

High

549825

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

689954

IL3RA
Interleukin-3 receptor subunit alpha

2

0

High-throughput

0.316

High

949264

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.316

High

1036224

NRG1
Pro-neuregulin-1, membrane-bound isoform

2

0

High-throughput

0.316

High

1081320

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.316

High

1094854

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

1108964

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1195241

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.316

High

1203319

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

1207549

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1208718

RTP2
Receptor-transporting protein 2

2

0

High-throughput

0.316

High

1209024

CAHM6
Calcium homeostasis modulator protein 6

2

0

High-throughput

0.316

High

1209034

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

2

0

High-throughput

0.316

High

1229385

LEMD1
LEM domain-containing protein 1

2

0

High-throughput

0.316

High

1244656

TMM65
Transmembrane protein 65

2

0

High-throughput

0.316

High

1248900

TM207
Transmembrane protein 207

2

0

High-throughput

0.316

High

1249813

BTNL9
Butyrophilin-like protein 9

2

0

High-throughput

0.316

High

1322703

F177A
Protein FAM177A1

2

0

High-throughput

0.316

High

1328161

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.316

High

1328164

CC4L
C-C motif chemokine 4-like

2

0

High-throughput

0.316

High

1328165

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

1328167

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

1328168

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

1328173

BSND
Barttin

2

0

High-throughput

0.316

High

1328177

SLAF6
SLAM family member 6

2

0

High-throughput

0.316

High

1328178

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

1328179

SMI19
Small integral membrane protein 19

2

0

High-throughput

0.316

High

1328183

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

0

High-throughput

0.316

High

1328186

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

1328191

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

1328192

HTAI2
Protein HTATIP2

2

0

High-throughput

0.316

High

1328194

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.316

High

1328197

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

1328198

FXYD6
FXYD domain-containing ion transport regulator 6

2

0

High-throughput

0.316

High

1328199

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

1328203

TNR27
Tumor necrosis factor receptor superfamily member 27

2

0

High-throughput

0.316

High

1328204

MRM3
rRNA methyltransferase 3, mitochondrial

2

0

High-throughput

0.316

High

1328209

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1328210

OTULL
Inactive ubiquitin thioesterase OTULINL

2

0

High-throughput

0.316

High

1328212

TM242
Transmembrane protein 242

2

0

High-throughput

0.316

High

1328216

NINJ2
Ninjurin-2

2

0

High-throughput

0.316

High

1328219

LPAR3
Lysophosphatidic acid receptor 3

2

0

High-throughput

0.316

High

1328232

JAM1
Junctional adhesion molecule A

2

0

High-throughput

0.316

High

1063982

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.268

Low

385965

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

1185994

SOAT
Sodium-dependent organic anion transporter

1

0

High-throughput

0.251

Low

1328163

TMIE
Transmembrane inner ear expressed protein

1

0

High-throughput

0.251

Low

1328170

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.251

Low

1328213

TBA8
Tubulin alpha-8 chain

1

0

High-throughput

0.251

Low

1328221

S23A2
Solute carrier family 23 member 2

1

0

High-throughput

0.251

Low

218458

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

404223

GCR
Glucocorticoid receptor

1

0

High-throughput

0.249

Low

589157

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695940

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768643

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

841022

FRK
Tyrosine-protein kinase FRK

1

0

High-throughput

0.249

Low

947227

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

1004825

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1328162

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.249

Low

1328174

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.249

Low

1328190

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.249

Low

1328218

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

1328222

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025