Protein: ENO1
Enolase 1 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase 1) (2-phosphoglycerate dehydratase 1)

Gene: ENO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 205
UniProt ID: P00924

Gene Ontology (top 5):
GO:0000015 - phosphopyruvate hydratase complex
GO:0000287 - magnesium ion binding
GO:0000324 - fungal-type vacuole
GO:0004634 - phosphopyruvate hydratase activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

342598

ENO1
Enolase 1

7

11

Small-scale

0.952

High

342599

ENO2
Enolase 2

2

11

High-throughput

0.754

High

342632

SSB1
Ribosome-associated molecular chaperone SSB1

3

7

High-throughput

0.650

High

342739

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

3

High-throughput

0.640

High

342642

HSC82
ATP-dependent molecular chaperone HSC82

3

7

High-throughput

0.633

High

342628

HSP71
Heat shock protein SSA1

3

7

High-throughput

0.624

High

342625

HSP77
Import motor subunit, mitochondrial

2

4

High-throughput

0.611

High

342666

KPC1
Protein kinase C-like 1

2

3

High-throughput

0.601

High

334562

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

2

9

Small-scale

0.584

High

342715

RPN10
26S proteasome regulatory subunit RPN10

2

1

Small-scale

0.584

High

342602

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.571

High

342629

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

342687

HSP7F
Heat shock protein homolog SSE1

2

10

High-throughput

0.552

High

342726

SSB2
Ribosome-associated molecular chaperone SSB2

2

7

High-throughput

0.552

High

342618

LTE1
Guanine nucleotide exchange factor LTE1

1

2

High-throughput

0.536

High

342688

PP12
Serine/threonine-protein phosphatase PP1-2

1

2

High-throughput

0.536

High

342732

MAD2
Mitotic spindle checkpoint component MAD2

1

1

High-throughput

0.536

High

342762

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

342719

TCPZ
T-complex protein 1 subunit zeta

2

1

High-throughput

0.521

High

342668

SIS1
Protein SIS1

1

2

High-throughput

0.515

High

342624

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

342612

KAPB
cAMP-dependent protein kinase type 2

1

3

High-throughput

0.500

High

342619

PBS2
MAP kinase kinase PBS2

1

5

High-throughput

0.500

High

342620

FUMH
Fumarate hydratase, mitochondrial

1

2

High-throughput

0.500

High

342635

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

High-throughput

0.500

High

342637

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

High-throughput

0.500

High

342649

PHO85
Cyclin-dependent protein kinase PHO85

1

5

High-throughput

0.500

High

342652

GBB
Guanine nucleotide-binding protein subunit beta

1

4

High-throughput

0.500

High

342654

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.500

High

342657

FKBP
FK506-binding protein 1

1

3

High-throughput

0.500

High

342659

PP11
Serine/threonine-protein phosphatase PP1-1

1

1

High-throughput

0.500

High

342660

PWP1
Periodic tryptophan protein 1

1

5

High-throughput

0.500

High

342673

GID7
Glucose-induced degradation protein 7

1

3

High-throughput

0.500

High

342674

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

2

High-throughput

0.500

High

342689

FIMB
Fimbrin

1

1

High-throughput

0.500

High

342705

IMB2
Importin subunit beta-2

1

1

High-throughput

0.500

High

342724

LIS1
Nuclear distribution protein PAC1

1

4

High-throughput

0.500

High

342731

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.500

High

342738

RIM15
Serine/threonine-protein kinase RIM15

1

5

High-throughput

0.500

High

342740

SA155
SIT4-associating protein SAP155

1

1

High-throughput

0.500

High

342752

SSK2
MAP kinase kinase kinase SSK2

1

2

High-throughput

0.500

High

342759

RHO4
GTP-binding protein RHO4

1

1

High-throughput

0.500

High

342769

STE20
Serine/threonine-protein kinase STE20

1

2

High-throughput

0.500

High

342781

IMH1
Golgin IMH1

1

5

High-throughput

0.500

High

342795

AP2M
AP-2 complex subunit mu

1

1

High-throughput

0.500

High

342648

SPO12
Sporulation-specific protein 12

1

1

High-throughput

0.489

High

342631

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.479

High

342639

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.479

High

342669

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.479

High

342685

CDC3
Cell division control protein 3

1

0

High-throughput

0.479

High

342686

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.479

High

342694

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.479

High

342700

VPS21
Vacuolar protein sorting-associated protein 21

1

0

High-throughput

0.479

High

342722

SLN1
Osmosensing histidine protein kinase SLN1

1

0

High-throughput

0.479

High

342733

PAC11
WD repeat-containing protein PAC11

1

0

High-throughput

0.479

High

342760

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.479

High

342766

UME1
Transcriptional regulatory protein UME1

1

0

High-throughput

0.479

High

342783

PSR2
Probable phosphatase PSR2

1

0

High-throughput

0.479

High

342791

GET3
ATPase GET3

1

0

High-throughput

0.479

High

334388

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

9

High-throughput

0.479

High

334849

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

9

High-throughput

0.479

High

336641

SODC
Superoxide dismutase [Cu-Zn]

1

5

High-throughput

0.479

High

339940

KPYK1
Pyruvate kinase 1

1

4

High-throughput

0.479

High

340563

PGK
Phosphoglycerate kinase

1

3

High-throughput

0.479

High

342600

TPIS
Triosephosphate isomerase

1

3

High-throughput

0.479

High

342601

PMG1
Phosphoglycerate mutase 1

1

3

High-throughput

0.479

High

342603

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

342604

HXKA
Hexokinase-1

1

5

High-throughput

0.479

High

342605

HXKB
Hexokinase-2

1

5

High-throughput

0.479

High

342606

VDAC1
Mitochondrial outer membrane protein porin 1

1

1

Small-scale

0.479

High

342607

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

1

High-throughput

0.479

High

342608

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

342609

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

342610

SC160
Protein SCP160

1

2

High-throughput

0.479

High

342611

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

342613

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

342614

KAD2
Adenylate kinase

1

1

High-throughput

0.479

High

342615

DHE4
NADP-specific glutamate dehydrogenase 1

1

1

High-throughput

0.479

High

342622

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

342623

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

342626

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

342627

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

342634

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.479

High

342636

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.479

High

342638

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.479

High

342641

TAL1
Transaldolase

1

1

High-throughput

0.479

High

342643

STI1
Heat shock protein STI1

1

5

High-throughput

0.479

High

342645

THRC
Threonine synthase

1

2

High-throughput

0.479

High

342653

PGTB1
Geranylgeranyl transferase type-1 subunit beta

1

1

High-throughput

0.479

High

342661

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

342663

HSP12
12 kDa heat shock protein

1

1

High-throughput

0.479

High

342664

TKT1
Transketolase 1

1

3

High-throughput

0.479

High

342670

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

342675

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

342679

DHOM
Homoserine dehydrogenase

1

1

High-throughput

0.479

High

342680

SYKM
Lysine--tRNA ligase, mitochondrial

1

3

Small-scale

0.479

High

342681

P5CR
Pyrroline-5-carboxylate reductase

1

2

High-throughput

0.479

High

342692

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

342695

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

342697

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

342698

TCTP
Translationally-controlled tumor protein homolog

1

2

High-throughput

0.479

High

342699

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

342707

AIM4
Altered inheritance of mitochondria protein 4

1

1

High-throughput

0.479

High

342712

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

342713

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

2

High-throughput

0.479

High

342714

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

342716

CH10
10 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.479

High

342721

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

342723

RSP5
E3 ubiquitin-protein ligase RSP5

1

7

High-throughput

0.479

High

342728

MLP2
Protein MLP2

1

8

High-throughput

0.479

High

342735

MMM1
Maintenance of mitochondrial morphology protein 1

1

1

High-throughput

0.479

High

342742

DUG1
Cys-Gly metallodipeptidase DUG1

1

1

High-throughput

0.479

High

342743

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

342747

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

342751

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

342754

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.479

High

342756

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

342761

NUM1
Nuclear migration protein NUM1

1

7

High-throughput

0.479

High

342763

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

342767

COFI
Cofilin

1

2

High-throughput

0.479

High

342768

TOM1
E3 ubiquitin-protein ligase TOM1

1

7

High-throughput

0.479

High

342770

OYE2
NADPH dehydrogenase 2

1

1

High-throughput

0.479

High

342777

PUR8
Adenylosuccinate lyase

1

2

High-throughput

0.479

High

342780

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

2

Small-scale

0.479

High

342784

ZEO1
Protein ZEO1

1

1

High-throughput

0.479

High

342785

SGO1
Shugoshin

1

1

High-throughput

0.479

High

342786

MCA1
Metacaspase-1

1

1

High-throughput

0.479

High

342788

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

342789

MDN1
Midasin

1

4

High-throughput

0.479

High

342794

SMC6
Structural maintenance of chromosomes protein 6

1

7

High-throughput

0.479

High

342630

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

342633

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.458

High

342651

ADT2
ADP,ATP carrier protein 2

1

0

Small-scale

0.458

High

342682

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

342684

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

342691

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

342737

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.458

High

342647

TUP1
General transcriptional corepressor TUP1

1

3

High-throughput

0.457

High

342655

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.457

High

342656

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

2

High-throughput

0.457

High

342667

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

5

High-throughput

0.457

High

342683

ARP2
Actin-related protein 2

1

2

High-throughput

0.457

High

342701

SWD2
COMPASS component SWD2

1

3

High-throughput

0.457

High

342704

AP3M
AP-3 complex subunit mu

1

1

High-throughput

0.457

High

342706

SIF2
SIR4-interacting protein SIF2

1

4

High-throughput

0.457

High

342709

ARPC1
Actin-related protein 2/3 complex subunit 1

1

4

High-throughput

0.457

High

342711

RCK1
Serine/threonine-protein kinase RCK1

1

5

High-throughput

0.457

High

342734

BUB1
Checkpoint serine/threonine-protein kinase BUB1

1

5

High-throughput

0.457

High

342736

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.457

High

342749

SEH1
Nucleoporin SEH1

1

5

High-throughput

0.457

High

342753

COPA
Coatomer subunit alpha

1

3

High-throughput

0.457

High

342771

WDR59
Maintenance of telomere capping protein 5

1

5

High-throughput

0.457

High

342772

UTP5
U3 small nucleolar RNA-associated protein 5

1

3

High-throughput

0.457

High

342776

ERB1
Ribosome biogenesis protein ERB1

1

3

High-throughput

0.457

High

342621

HSP73
Heat shock protein SSA3

1

7

High-throughput

0.445

High

342640

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.445

High

342646

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

342658

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.445

High

342672

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

342708

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

2

High-throughput

0.445

High

342720

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

342725

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

342745

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.445

High

342748

CWC23
Pre-mRNA-splicing factor CWC23

1

2

High-throughput

0.445

High

342765

ULP1
Ubiquitin-like-specific protease 1

1

4

High-throughput

0.439

High

342676

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

342677

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

342678

TF3B
Transcription factor IIIB 70 kDa subunit

1

4

High-throughput

0.437

High

342696

IXR1
Intrastrand cross-link recognition protein

1

3

Small-scale

0.437

High

342703

HMT1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.437

High

342710

YGP1
Protein YGP1

1

1

High-throughput

0.437

High

342729

ULP2
Ubiquitin-like-specific protease 2

1

4

Small-scale

0.437

High

342746

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

342757

ACT
Actin

1

1

Small-scale

0.437

High

342764

MLP1
Protein MLP1

1

8

High-throughput

0.437

High

342779

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.437

High

342787

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

342792

SMT3
Ubiquitin-like protein SMT3

1

4

High-throughput

0.437

High

342644

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

342702

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.426

High

342750

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.426

High

342774

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

342717

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

342718

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.407

High

342730

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.407

High

342741

ERJ5
ER-localized J domain-containing protein 5

1

1

High-throughput

0.407

High

342616

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

2

0

High-throughput

0.313

High

342617

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.261

Low

342665

VAN1
Mannan polymerase I complex VAN1 subunit

1

0

High-throughput

0.261

Low

342671

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.261

Low

342690

CDC13
Cell division control protein 13

1

0

High-throughput

0.261

Low

342693

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

342758

YE066
Putative uncharacterized protein YER066C-A

1

0

High-throughput

0.261

Low

342775

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.261

Low

342782

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.261

Low

342793

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.261

Low

342650

TPM1
Tropomyosin-1

1

0

Small-scale

0.249

Low

342662

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

342778

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

342727

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.232

Low

342744

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low

342755

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low

342773

BUD22
Bud site selection protein 22

1

0

High-throughput

0.232

Low

342790

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024