Protein: SEC2
Rab guanine nucleotide exchange factor SEC2 (GDP-GTP exchange factor SEC2)

Gene: SEC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 99
UniProt ID: P17065

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005934 - cellular bud tip
GO:0005935 - cellular bud neck
GO:0006887 - exocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

429167

SEC4
Ras-related protein SEC4

11

5

Small-scale

0.979

High

563969

YPT32
GTP-binding protein YPT32/YPT11

4

4

Small-scale

0.888

High

563918

SEC2
Rab guanine nucleotide exchange factor SEC2

4

4

Small-scale

0.881

High

563923

SEC15
Exocyst complex component SEC15

5

0

Small-scale

0.684

High

563973

CBK1
Serine/threonine-protein kinase CBK1

2

1

Small-scale

0.625

High

563925

KC12
Casein kinase I homolog 2

2

2

Small-scale

0.619

High

563951

YPT31
GTP-binding protein YPT31/YPT8

1

4

Small-scale

0.618

High

563971

ATG1
Serine/threonine-protein kinase ATG1

3

0

Small-scale

0.618

High

563949

AKL1
Serine/threonine-protein kinase AKL1

2

2

High-throughput

0.602

High

563955

KSP1
Serine/threonine-protein kinase KSP1

2

2

High-throughput

0.602

High

446108

MYO1
Myosin-1

2

0

Small-scale

0.583

High

563990

VAM6
Vacuolar morphogenesis protein 6

2

0

High-throughput

0.561

High

563937

SMY1
Kinesin-related protein SMY1

2

0

Small-scale

0.559

High

493124

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

563987

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.537

High

563962

FKH1
Fork head protein homolog 1

1

1

High-throughput

0.536

High

410892

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.513

High

563933

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

563948

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.513

High

563989

ELP1
Elongator complex protein 1

1

0

Small-scale

0.504

High

339418

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.501

High

412443

KIN28
Serine/threonine-protein kinase KIN28

1

1

High-throughput

0.501

High

563921

DBF2
Cell cycle protein kinase DBF2

1

1

High-throughput

0.501

High

563927

KCC4
Probable serine/threonine-protein kinase KCC4

1

3

High-throughput

0.501

High

563943

SWE1
Mitosis inhibitor protein kinase SWE1

1

1

High-throughput

0.501

High

563945

HSL1
Probable serine/threonine-protein kinase HSL1

1

3

High-throughput

0.501

High

563952

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

1

High-throughput

0.501

High

563963

PRK1
Actin-regulating kinase PRK1

1

3

High-throughput

0.501

High

563974

ARK1
Actin-regulating kinase 1

1

4

High-throughput

0.501

High

563977

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

2

High-throughput

0.501

High

563979

KIN4
Serine/threonine-protein kinase KIN4

1

3

High-throughput

0.501

High

563982

STE20
Serine/threonine-protein kinase STE20

1

2

High-throughput

0.501

High

563993

GIN4
Serine/threonine-protein kinase GIN4

1

4

High-throughput

0.501

High

412643

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

419794

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

539297

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.480

High

563970

SCY1
Protein kinase-like protein SCY1

1

0

High-throughput

0.480

High

563976

SEC5
Exocyst complex component SEC5

1

0

Small-scale

0.480

High

563991

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.480

High

563922

RAD53
Serine/threonine-protein kinase RAD53

1

2

Small-scale

0.479

High

563995

TRS33
Trafficking protein particle complex subunit 33

1

2

Small-scale

0.479

High

563944

NIP80
Protein NIP100

1

0

High-throughput

0.460

High

563957

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.460

High

563928

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.458

High

563934

SEC1
Protein transport protein SEC1

1

0

Small-scale

0.458

High

563941

SEC8
Exocyst complex component SEC8

1

0

Small-scale

0.458

High

563942

TRS65
Trafficking protein particle complex II-specific subunit 65

1

0

Small-scale

0.458

High

563960

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

563967

MOB2
CBK1 kinase activator protein MOB2

1

0

Small-scale

0.458

High

563992

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.458

High

563920

MCK1
Protein kinase MCK1

1

1

High-throughput

0.457

High

563924

KC11
Casein kinase I homolog 1

1

2

High-throughput

0.457

High

563929

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.457

High

563931

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.457

High

563936

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.457

High

563940

IME2
Meiosis induction protein kinase IME2/SME1

1

3

High-throughput

0.457

High

563953

RCK1
Serine/threonine-protein kinase RCK1

1

2

High-throughput

0.457

High

563954

RCK2
Serine/threonine-protein kinase RCK2

1

2

High-throughput

0.457

High

563980

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

1

High-throughput

0.457

High

563994

SKM1
Serine/threonine-protein kinase SKM1

1

3

High-throughput

0.457

High

490248

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

563978

SED5
Integral membrane protein SED5

1

1

High-throughput

0.439

High

563981

YMZ2
WD repeat-containing protein YMR102C

1

1

High-throughput

0.437

High

367703

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

510167

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

540019

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.426

High

543136

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.426

High

563959

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

563919

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.407

High

563938

MET4
Transcriptional activator of sulfur metabolism MET4

2

0

High-throughput

0.310

High

560550

BIP
Endoplasmic reticulum chaperone BiP

2

0

High-throughput

0.300

High

454162

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.279

Low

563939

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.279

Low

563950

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.279

Low

563956

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.279

Low

563966

GCN20
Protein GCN20

1

0

High-throughput

0.279

Low

563975

ACT
Actin

1

0

High-throughput

0.279

Low

563983

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.279

Low

563935

COPG
Coatomer subunit gamma

1

0

High-throughput

0.269

Low

563926

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.251

Low

563946

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

563947

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

563961

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.251

Low

563964

MAD1
Spindle assembly checkpoint component MAD1

1

0

High-throughput

0.251

Low

563968

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

563972

PRS10
26S proteasome subunit RPT4

1

0

High-throughput

0.251

Low

563984

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.251

Low

563986

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

563988

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.251

Low

448478

PRTB
Cerevisin

1

0

High-throughput

0.249

Low

563930

CBPS
Carboxypeptidase S

1

0

High-throughput

0.249

Low

563932

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

563985

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.249

Low

340004

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

360726

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

555785

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

563958

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

563965

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024