Protein: SAM35
Sorting assembly machinery 35 kDa subunit (Mitochondrial 38 kDa outer membrane protein) (TOB complex 38 kDa subunit)

Gene: SAM35
Organism: Saccharomyces cerevisiae S288C
Interactions: 121
UniProt ID: P14693

Gene Ontology (top 5):
GO:0001401 - SAM complex
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0030150 - protein import into mitochondrial matrix
GO:0045040 - protein insertion into mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

574914

SAM50
Sorting assembly machinery 50 kDa subunit

8

0

Small-scale

0.918

High

574851

TOM40
Mitochondrial import receptor subunit TOM40

7

0

Small-scale

0.715

High

574903

SAM37
Sorting assembly machinery 37 kDa subunit

8

0

Small-scale

0.715

High

574848

MDM10
Mitochondrial distribution and morphology protein 10

8

0

Small-scale

0.714

High

417014

VDAC1
Non-selective voltage-gated ion channel 1

5

0

Small-scale

0.678

High

574902

TOM22
Mitochondrial import receptor subunit TOM22

4

0

Small-scale

0.667

High

574874

MIC60
MICOS complex subunit MIC60

3

0

Small-scale

0.606

High

574915

ALO
D-arabinono-1,4-lactone oxidase

2

0

High-throughput

0.587

High

574916

TOM5
Mitochondrial import receptor subunit TOM5

2

0

Small-scale

0.547

High

574950

EMR1
ERMES regulator 1

1

0

Small-scale

0.480

High

382817

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

510144

HSP77
Import motor subunit, mitochondrial

1

0

Small-scale

0.458

High

574846

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

Small-scale

0.458

High

574854

MGR1
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1

1

0

High-throughput

0.458

High

574866

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

Small-scale

0.458

High

574898

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

574909

TOM7
Mitochondrial import receptor subunit TOM7

1

0

Small-scale

0.458

High

574926

UBX2
UBX domain-containing protein 2

1

0

Small-scale

0.458

High

574930

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.458

High

574931

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

0

High-throughput

0.458

High

574936

MIM1
Mitochondrial import protein 1

1

0

Small-scale

0.458

High

574952

MDM12
Mitochondrial distribution and morphology protein 12

1

0

Small-scale

0.458

High

448625

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.438

High

525808

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.438

High

574860

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.438

High

574862

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

0

High-throughput

0.438

High

574863

YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1

1

0

High-throughput

0.438

High

574865

PP2A4
Serine/threonine-protein phosphatase PP2A-like PPG1

1

0

High-throughput

0.438

High

574879

TCM62
Mitochondrial chaperone TCM62

1

0

High-throughput

0.438

High

574901

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.438

High

574904

KPYK2
Pyruvate kinase 2

1

0

High-throughput

0.438

High

574907

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.438

High

574920

GIP3
GLC7-interacting protein 3

1

0

High-throughput

0.438

High

574927

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.438

High

574933

POS5
NADH kinase POS5, mitochondrial

1

0

High-throughput

0.438

High

574942

HOSM
Homocitrate synthase, mitochondrial

1

0

High-throughput

0.438

High

574948

MRX4
MIOREX complex component 4

1

0

High-throughput

0.438

High

574868

TOM6
Mitochondrial import receptor subunit TOM6

1

0

Small-scale

0.426

High

574908

MST27
Multicopy suppressor of SEC21 protein 27

1

1

High-throughput

0.417

High

574949

SKS1
Serine/threonine-protein kinase SKS1

1

1

High-throughput

0.417

High

574913

CARME
Carnosine N-methyltransferase

2

0

High-throughput

0.307

High

574924

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.265

Low

574877

PET10
Protein PET10

1

0

High-throughput

0.251

Low

574857

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

574937

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.249

Low

574941

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

366034

CBPY
Carboxypeptidase Y

1

0

High-throughput

0.238

Low

444412

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.238

Low

454066

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.238

Low

454688

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

High-throughput

0.238

Low

486395

TBA3
Tubulin alpha-3 chain

1

0

High-throughput

0.238

Low

503711

YB39B
Uncharacterized protein YBL039W-B

1

0

High-throughput

0.238

Low

553902

WHI2
Growth regulation protein

1

0

High-throughput

0.238

Low

574847

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.238

Low

574849

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.238

Low

574850

STE11
Serine/threonine-protein kinase STE11

1

0

High-throughput

0.238

Low

574852

ADP1
Probable ATP-dependent permease

1

0

High-throughput

0.238

Low

574853

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.238

Low

574855

PEX34
Peroxisomal membrane protein PEX34

1

0

High-throughput

0.238

Low

574856

SRB8
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.238

Low

574858

UBCX
Ubiquitin-conjugating enzyme E2-21 kDa

1

0

High-throughput

0.238

Low

574859

PSB5
Proteasome subunit beta type-5

1

0

High-throughput

0.238

Low

574861

HIR1
Protein HIR1

1

0

High-throughput

0.238

Low

574864

FZF1
Zinc finger protein FZF1

1

0

High-throughput

0.238

Low

574867

YGB5
Uncharacterized protein YGL015C

1

0

High-throughput

0.238

Low

574869

SPO23
Sporulation protein 23

1

0

High-throughput

0.238

Low

574870

PPAB
Acid phosphatase PHO11

1

0

High-throughput

0.238

Low

574871

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.238

Low

574872

MNN4
Mannosyltransferase regulator 4

1

0

High-throughput

0.238

Low

574873

SHE2
SWI5-dependent HO expression protein 2

1

0

High-throughput

0.238

Low

574875

SPC34
DASH complex subunit SPC34

1

0

High-throughput

0.238

Low

574876

SHB17
Sedoheptulose 1,7-bisphosphatase

1

0

High-throughput

0.238

Low

574878

YBE4
Uncharacterized protein YBL044W

1

0

High-throughput

0.238

Low

574880

SLM4
Protein SLM4

1

0

High-throughput

0.238

Low

574881

AIM3
Altered inheritance of mitochondria protein 3

1

0

High-throughput

0.238

Low

574882

HSM3
DNA mismatch repair protein HSM3

1

0

High-throughput

0.238

Low

574883

YHE2
Putative uncharacterized protein YHL042W

1

0

High-throughput

0.238

Low

574884

YHB7
Uncharacterized membrane protein YHL071W

1

0

High-throughput

0.238

Low

574885

SHU1
Suppressor of HU sensitivity involved in recombination protein 1

1

0

High-throughput

0.238

Low

574886

SFB3
SED5-binding protein 3

1

0

High-throughput

0.238

Low

574887

SNF11
Transcription regulatory protein SNF11

1

0

High-throughput

0.238

Low

574888

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

0

High-throughput

0.238

Low

574889

ERP2
Protein ERP2

1

0

High-throughput

0.238

Low

574890

YEI6
Uncharacterized protein YEL076C

1

0

High-throughput

0.238

Low

574892

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

0

High-throughput

0.238

Low

574893

GAT2
Protein GAT2

1

0

High-throughput

0.238

Low

574894

SIM1
Probable secreted beta-glucosidase SIM1

1

0

High-throughput

0.238

Low

574895

FYV10
GID complex subunit 9

1

0

High-throughput

0.238

Low

574896

PSMD9
Probable 26S proteasome regulatory subunit p27

1

0

High-throughput

0.238

Low

574897

GYP8
GTPase-activating protein GYP8

1

0

High-throughput

0.238

Low

574899

CIS3
Cell wall mannoprotein CIS3

1

0

High-throughput

0.238

Low

574900

YJL8
Uncharacterized protein YJL118W

1

0

High-throughput

0.238

Low

574905

YIP5
Protein YIP5

1

0

High-throughput

0.238

Low

574906

YGL7
Uncharacterized protein YGL117W

1

0

High-throughput

0.238

Low

574910

ZNG1
Zinc-regulated GTPase metalloprotein activator 1

1

0

High-throughput

0.238

Low

574911

BSC5
Bypass of stop codon protein 5

1

0

High-throughput

0.238

Low

574912

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.238

Low

574917

HPC2
Histone promoter control protein 2

1

0

High-throughput

0.238

Low

574918

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

574919

UTP17
NET1-associated nuclear protein 1

1

0

High-throughput

0.238

Low

574921

RMT2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.238

Low

574922

YMK8
Uncharacterized protein YML108W

1

0

High-throughput

0.238

Low

574923

YM09
Uncharacterized protein YMR122C

1

0

High-throughput

0.238

Low

574925

URH1
Uridine nucleosidase

1

0

High-throughput

0.238

Low

574928

PIG1
Serine/threonine-protein phosphatase 1 regulatory subunit PIG1

1

0

High-throughput

0.238

Low

574929

SEC10
Exocyst complex component SEC10

1

0

High-throughput

0.238

Low

574934

HBT1
Protein HBT1

1

0

High-throughput

0.238

Low

574935

XYL2
D-xylulose reductase

1

0

High-throughput

0.238

Low

574938

OSW1
Outer spore wall protein 1

1

0

High-throughput

0.238

Low

574939

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.238

Low

574940

AP1G1
AP-1 complex subunit gamma-1

1

0

High-throughput

0.238

Low

574943

RPIA
Ribose-5-phosphate isomerase

1

0

High-throughput

0.238

Low

574944

RLM1
Transcription factor RLM1

1

0

High-throughput

0.238

Low

574945

SUL2
Sulfate permease 2

1

0

High-throughput

0.238

Low

574946

IES3
Ino eighty subunit 3

1

0

High-throughput

0.238

Low

574947

APTH1
Acyl-protein thioesterase 1

1

0

High-throughput

0.238

Low

574951

YM135
Putative uncharacterized protein YMR135W-A

1

0

High-throughput

0.238

Low

574953

GIN11
Putative UPF0320 protein YLL065W

1

0

High-throughput

0.238

Low

574891

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low

574932

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025