Protein: RAD59
DNA repair protein RAD59

Gene: RAD59
Organism: Saccharomyces cerevisiae S288C
Interactions: 85
UniProt ID: Q12223

Gene Ontology (top 5):
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

419641

RAD52
DNA repair and recombination protein RAD52

11

6

Small-scale

0.976

High

1015342

RAD59
DNA repair protein RAD59

2

6

Small-scale

0.800

High

704954

PGM1
Phosphoglucomutase 1

1

1

High-throughput

0.536

High

730689

EF1G2
Elongation factor 1-gamma 2

1

1

High-throughput

0.536

High

739504

PGM2
Phosphoglucomutase 2

1

1

High-throughput

0.536

High

766276

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.536

High

768405

GPP2
Glycerol-1-phosphate phosphohydrolase 2

1

1

High-throughput

0.536

High

783309

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

1

High-throughput

0.536

High

523461

SRS2
ATP-dependent DNA helicase SRS2

1

1

Small-scale

0.527

High

987577

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

1

Small-scale

0.527

High

500662

AK
Aspartokinase

1

0

High-throughput

0.513

High

558325

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.513

High

608731

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.513

High

679841

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.513

High

703864

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

High-throughput

0.513

High

710524

PP2C3
Protein phosphatase 2C homolog 3

1

0

High-throughput

0.513

High

747608

OPY1
Protein OPY1

1

0

High-throughput

0.513

High

765670

BEM2
GTPase-activating protein BEM2/IPL2

1

0

High-throughput

0.513

High

860642

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.513

High

976941

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.513

High

977027

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

0

High-throughput

0.513

High

1015344

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.513

High

841452

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.501

High

381501

GAL1
Galactokinase

1

1

High-throughput

0.500

High

389340

HXKA
Hexokinase-1

1

1

High-throughput

0.500

High

424765

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.500

High

440119

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.500

High

454501

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.500

High

556376

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.500

High

560829

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.500

High

588264

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.500

High

629078

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.500

High

633687

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.500

High

636778

CDC48
Cell division control protein 48

1

1

High-throughput

0.500

High

665112

BMH1
Protein BMH1

1

1

High-throughput

0.500

High

715869

MDJ1
DnaJ homolog 1, mitochondrial

1

1

High-throughput

0.500

High

887716

ACT
Actin

1

1

High-throughput

0.500

High

1015345

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.500

High

975995

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.493

High

575901

ADT3
ADP,ATP carrier protein 3

1

1

High-throughput

0.489

High

690993

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

1

High-throughput

0.489

High

860453

RSC1
Chromatin structure-remodeling complex subunit RSC1

1

2

Small-scale

0.481

High

342400

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.479

High

361082

TBB
Tubulin beta chain

1

0

High-throughput

0.479

High

498617

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

554771

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

562454

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.479

High

693375

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.479

High

699381

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.479

High

767763

IMB4
Importin subunit beta-4

1

0

High-throughput

0.479

High

811495

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.479

High

968096

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.479

High

607360

RFA1
Replication factor A protein 1

1

4

Small-scale

0.479

High

632588

RAD51
DNA repair protein RAD51

1

6

Small-scale

0.479

High

644783

RFA2
Replication factor A protein 2

1

3

Small-scale

0.479

High

902136

H3
Histone H3

1

1

High-throughput

0.479

High

1015346

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

663659

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

342139

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.457

High

397627

OTC
Ornithine carbamoyltransferase

1

2

High-throughput

0.457

High

570733

HXKG
Glucokinase-1

1

1

High-throughput

0.457

High

576028

ADT2
ADP,ATP carrier protein 2

1

1

High-throughput

0.457

High

867535

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

1

High-throughput

0.457

High

478610

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.445

High

492826

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

495290

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

513185

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

1015343

SMT3
Ubiquitin-like protein SMT3

1

3

Small-scale

0.408

High

693263

SCM4
Protein SCM4

2

0

Small-scale

0.295

High

796987

SNZ3
Probable pyridoxal 5'-phosphate synthase subunit SNZ3

2

0

Small-scale

0.295

High

426414

PMM
Phosphomannomutase

1

0

High-throughput

0.279

Low

427310

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.279

Low

448528

PRTB
Cerevisin

1

0

High-throughput

0.279

Low

696837

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.279

Low

743844

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

750767

YPT31
GTP-binding protein YPT31/YPT8

1

0

High-throughput

0.279

Low

784447

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

343710

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

378410

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

381727

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.261

Low

549693

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

581327

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

496106

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.238

Low

1015347

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024