Protein: PMA2
Plasma membrane ATPase 2 (EC 7.1.2.1) (Proton pump 2)

Gene: PMA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P19657

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane
GO:0008553 - P-type proton-exporting transporter activity
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533156

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

3

High-throughput

0.536

High

624732

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

10

High-throughput

0.489

High

624817

RBX1
RING-box protein HRT1

1

3

High-throughput

0.489

High

441030

KAPA
cAMP-dependent protein kinase type 1

1

3

High-throughput

0.479

High

510176

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.479

High

511074

COS3
Protein COS3

1

1

High-throughput

0.479

High

556556

STE6
Alpha-factor-transporting ATPase

1

4

High-throughput

0.479

High

584337

GCN2
eIF-2-alpha kinase GCN2

1

3

High-throughput

0.479

High

618847

GAP1
General amino-acid permease GAP1

1

3

High-throughput

0.479

High

624721

BEM1
Bud emergence protein 1

1

4

High-throughput

0.479

High

624722

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

2

High-throughput

0.479

High

624728

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

624729

SLA2
Protein SLA2

1

3

High-throughput

0.479

High

624734

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

624745

HXT5
Probable glucose transporter HXT5

1

7

High-throughput

0.479

High

624752

KC13
Casein kinase I homolog 3

1

10

High-throughput

0.479

High

624756

WRIP1
DNA-dependent ATPase MGS1

1

4

High-throughput

0.479

High

624758

CYB5
Cytochrome b5

1

1

High-throughput

0.479

High

624769

MID1
Stretch-activated cation channel MID1

1

1

Small-scale

0.479

High

624778

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

624786

VSB1
Vacuolar basic amino acid transporter VSB1

1

3

High-throughput

0.479

High

624794

ORC1
Origin recognition complex subunit 1

1

4

High-throughput

0.479

High

624796

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.479

High

624797

YP109
ABC1 family protein YPL109C, mitochondrial

1

5

High-throughput

0.479

High

624802

YHM2
Citrate/oxoglutarate carrier protein

1

4

High-throughput

0.479

High

624807

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

624810

EIS1
Eisosome protein 1

1

1

High-throughput

0.479

High

624827

RTN2
Reticulon-like protein 2

1

1

High-throughput

0.479

High

624831

SMC6
Structural maintenance of chromosomes protein 6

1

3

High-throughput

0.479

High

94533

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.458

High

150206

CCW14
Covalently-linked cell wall protein 14

1

0

High-throughput

0.458

High

357691

CYC1
Cytochrome c isoform 1

1

0

High-throughput

0.458

High

360776

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.458

High

590523

HSP26
Heat shock protein 26

1

0

High-throughput

0.458

High

624717

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

624719

CBPS
Carboxypeptidase S

1

0

High-throughput

0.458

High

624725

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.458

High

624743

FZO1
Mitofusin FZO1

1

0

High-throughput

0.458

High

624751

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

624755

SPI1
Uncharacterized cell wall protein SPI1

1

0

High-throughput

0.458

High

624780

DXO
Decapping nuclease RAI1

1

0

High-throughput

0.458

High

624784

YGI2
Uncharacterized protein YGL082W

1

0

High-throughput

0.458

High

624792

NRK1
Nicotinamide riboside kinase

1

0

High-throughput

0.458

High

624811

UPS1
Protein UPS1, mitochondrial

1

0

High-throughput

0.458

High

624813

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.458

High

624814

HBT1
Protein HBT1

1

0

High-throughput

0.458

High

624818

TYW4
tRNA wybutosine-synthesizing protein 4

1

0

High-throughput

0.458

High

624822

PIN2
[PSI+] induction protein 2

1

0

High-throughput

0.458

High

624826

ATP14
ATP synthase subunit H, mitochondrial

1

0

High-throughput

0.458

High

624828

FMP16
Protein FMP16, mitochondrial

1

0

High-throughput

0.458

High

624833

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

1

0

High-throughput

0.458

High

434807

RS3
Small ribosomal subunit protein uS3

1

3

Small-scale

0.437

High

445313

CDC31
Cell division control protein 31

1

7

Small-scale

0.437

High

514095

RS16B
Small ribosomal subunit protein uS9B

1

1

High-throughput

0.437

High

624713

CG11
G1/S-specific cyclin CLN1

1

2

High-throughput

0.437

High

624714

MAK11
Protein MAK11

1

5

High-throughput

0.437

High

624715

VPS3
Vacuolar protein sorting-associated protein 3

1

1

Small-scale

0.437

High

624723

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

1

High-throughput

0.437

High

624724

GPI3
Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit

1

1

High-throughput

0.437

High

624727

FZF1
Zinc finger protein FZF1

1

3

High-throughput

0.437

High

624730

IXR1
Intrastrand cross-link recognition protein

1

4

Small-scale

0.437

High

624731

YKG3
Uncharacterized protein YKL063C

1

1

High-throughput

0.437

High

624733

DID4
DOA4-independent degradation protein 4

1

1

High-throughput

0.437

High

624736

RL1D1
Ribosome biogenesis protein UTP30

1

1

High-throughput

0.437

High

624738

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.437

High

624739

NRG2
Probable transcriptional regulator NRG2

1

1

High-throughput

0.437

High

624741

CST26
2-acyl-1-lysophosphatidylinositol acyltransferase

1

2

High-throughput

0.437

High

624746

LAG1
Ceramide synthase LAG1

1

1

High-throughput

0.437

High

624762

NDC80
Kinetochore protein NDC80

1

3

High-throughput

0.437

High

624764

SGN1
RNA-binding protein SGN1

1

1

High-throughput

0.437

High

624765

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

624766

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

624770

PFA3
Palmitoyltransferase PFA3

1

1

High-throughput

0.437

High

624771

COS4
Protein COS4

1

1

High-throughput

0.437

High

624773

AP3B
AP-3 complex subunit beta

1

3

High-throughput

0.437

High

624776

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

624785

TWF1
Twinfilin-1

1

1

High-throughput

0.437

High

624787

YG3A
Uncharacterized protein YGR130C

1

6

High-throughput

0.437

High

624789

BIO5
7-keto 8-aminopelargonic acid transporter

1

4

High-throughput

0.437

High

624791

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

624793

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

Small-scale

0.437

High

624799

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

6

High-throughput

0.437

High

624803

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.437

High

624816

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

5

High-throughput

0.437

High

624819

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

624829

DFM1
DER1-like family member protein 1

1

4

High-throughput

0.437

High

509386

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

High-throughput

0.407

High

449278

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.249

Low

449395

SPT2
Protein SPT2

1

0

High-throughput

0.249

Low

624716

CG21
G2/mitotic-specific cyclin-1

1

0

High-throughput

0.249

Low

624718

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.249

Low

624720

PEP3
Vacuolar membrane protein PEP3

1

0

High-throughput

0.249

Low

624726

CDC12
Cell division control protein 12

1

0

High-throughput

0.249

Low

624735

VPS51
Vacuolar protein sorting-associated protein 51

1

0

High-throughput

0.249

Low

624737

NU133
Nucleoporin NUP133

1

0

High-throughput

0.249

Low

624740

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.249

Low

624742

ICS2
Increased copper sensitivity protein 2

1

0

High-throughput

0.249

Low

624744

MTC4
Maintenance of telomere capping protein 4

1

0

High-throughput

0.249

Low

624747

OTU2
OTU domain-containing protein 2

1

0

High-throughput

0.249

Low

624748

YHK5
Putative uncharacterized protein YHR045W

1

0

High-throughput

0.249

Low

624749

YHP7
Uncharacterized protein YHR097C

1

0

High-throughput

0.249

Low

624750

FLC2
Flavin carrier protein 2

1

0

High-throughput

0.249

Low

624753

YEI3
Uncharacterized protein YEL073C

1

0

High-throughput

0.249

Low

624754

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.249

Low

624757

IES2
Ino eighty subunit 2

1

0

High-throughput

0.249

Low

624759

DLS1
Protein DLS1

1

0

High-throughput

0.249

Low

624760

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.249

Low

624761

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.249

Low

624763

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.249

Low

624767

REE1
Regulation of enolase protein 1

1

0

High-throughput

0.249

Low

624768

GTS1
Protein GTS1

1

0

High-throughput

0.249

Low

624772

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.249

Low

624774

RRP41
Exosome complex component SKI6

1

0

High-throughput

0.249

Low

624775

RSF2
Respiration factor 2

1

0

High-throughput

0.249

Low

624777

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.249

Low

624779

SIP18
Protein SIP18

1

0

High-throughput

0.249

Low

624781

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.249

Low

624782

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.249

Low

624783

USE1
Protein transport protein USE1

1

0

High-throughput

0.249

Low

624788

SOL4
6-phosphogluconolactonase 4

1

0

High-throughput

0.249

Low

624790

CA120
CCR4-NOT transcriptional complex subunit CAF120

1

0

High-throughput

0.249

Low

624795

RL34A
Large ribosomal subunit protein eL34A

1

0

High-throughput

0.249

Low

624798

SGF11
SAGA complex subunit SGF11

1

0

High-throughput

0.249

Low

624800

TFB3
RNA polymerase II transcription factor B subunit 3

1

0

High-throughput

0.249

Low

624801

MSS11
Transcription activator MSS11

1

0

High-throughput

0.249

Low

624804

ICY1
Interacting with cytoskeleton protein 1

1

0

High-throughput

0.249

Low

624805

CSM3
Chromosome segregation in meiosis protein 3

1

0

High-throughput

0.249

Low

624806

YDR22
SVF1-like protein YDR222W

1

0

High-throughput

0.249

Low

624808

NTE1
Lysophospholipase NTE1

1

0

High-throughput

0.249

Low

624809

BCH1
Protein BCH1

1

0

High-throughput

0.249

Low

624812

CSA1
CDC5 pindle pole body anchor protein 1

1

0

High-throughput

0.249

Low

624815

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.249

Low

624820

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.249

Low

624821

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

0

High-throughput

0.249

Low

624823

CFT2
Cleavage factor two protein 2

1

0

High-throughput

0.249

Low

624824

EMA19
Efficient mitochondria targeting-associated protein 19

1

0

High-throughput

0.249

Low

624825

YL054
Uncharacterized transcriptional regulatory protein YLL054C

1

0

High-throughput

0.249

Low

624830

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.249

Low

624832

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.249

Low

624834

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025