Protein: PPID
Peptidyl-prolyl cis-trans isomerase CPR6 (PPIase CPR6) (EC 5.2.1.8) (Rotamase CPR6)

Gene: PPID, CPR6
Organism: Saccharomyces cerevisiae S288C
Interactions: 147
UniProt ID: P53691

Gene Ontology (top 5):
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005737 - cytoplasm
GO:0006457 - protein folding
GO:0016018 - cyclosporin A binding
GO:0042026 - protein refolding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393114

HSP82
ATP-dependent molecular chaperone HSP82

18

12

Small-scale

0.766

High

579820

HSC82
ATP-dependent molecular chaperone HSC82

12

12

Small-scale

0.758

High

739428

ZUO1
Zuotin

2

4

Small-scale

0.754

High

453717

PYR1
Multifunctional protein URA2

6

3

Small-scale

0.726

High

524716

HSP71
Heat shock protein SSA1

6

15

Small-scale

0.719

High

919577

YG5B
Uncharacterized RNA-binding protein YGR250C

1

2

High-throughput

0.698

High

727218

HS104
Heat shock protein 104

4

4

Small-scale

0.678

High

745978

PP2A4
Serine/threonine-protein phosphatase PP2A-like PPG1

1

1

High-throughput

0.656

High

704634

SBA1
Co-chaperone protein SBA1

3

3

Small-scale

0.647

High

739899

RPD3
Histone deacetylase RPD3

2

7

Small-scale

0.620

High

922697

AHA1
Hsp90 co-chaperone AHA1

2

1

Small-scale

0.618

High

670974

SIS1
Protein SIS1

1

2

High-throughput

0.618

High

741037

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

High-throughput

0.618

High

865381

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

9

Small-scale

0.618

High

804783

NADE
Glutamine-dependent NAD(+) synthetase

2

0

High-throughput

0.595

High

811362

CAJ1
Protein CAJ1

1

0

High-throughput

0.586

High

527312

HSP72
Heat shock protein SSA2

2

15

High-throughput

0.571

High

545756

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

Small-scale

0.571

High

585644

STI1
Heat shock protein STI1

1

2

Small-scale

0.569

High

819388

SSB2
Ribosome-associated molecular chaperone SSB2

2

13

High-throughput

0.552

High

776623

DEF1
RNA polymerase II degradation factor 1

1

2

High-throughput

0.541

High

358416

ADH2
Alcohol dehydrogenase 2

1

1

High-throughput

0.536

High

437943

KAPC
cAMP-dependent protein kinase type 3

1

2

High-throughput

0.536

High

470150

SPS1
Sporulation-specific protein 1

1

2

High-throughput

0.536

High

651970

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

1

High-throughput

0.536

High

750876

PRS6B
26S proteasome regulatory subunit 6B homolog

1

2

High-throughput

0.536

High

922678

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

3

High-throughput

0.536

High

850125

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

2

High-throughput

0.533

High

919416

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.518

High

863678

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.513

High

919636

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.513

High

922675

CA120
CCR4-NOT transcriptional complex subunit CAF120

1

0

High-throughput

0.513

High

922692

RCN2
Regulator of calcineurin 2

1

0

High-throughput

0.513

High

922695

SLP1
Uncharacterized protein SLP1

1

0

High-throughput

0.513

High

441205

KAPA
cAMP-dependent protein kinase type 1

1

2

High-throughput

0.501

High

394779

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.500

High

416465

HXKA
Hexokinase-1

1

1

High-throughput

0.500

High

836624

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

1

High-throughput

0.494

High

922684

WDR59
Maintenance of telomere capping protein 5

1

3

High-throughput

0.489

High

922685

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.489

High

922698

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.481

High

416143

SYTC
Threonine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

416271

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

427385

RLA0
Large ribosomal subunit protein uL10

1

1

Small-scale

0.479

High

435258

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.479

High

438747

SC160
Protein SCP160

1

2

High-throughput

0.479

High

514758

RS18A
Small ribosomal subunit protein uS13A

1

1

Small-scale

0.479

High

581888

SYKC
Lysine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

709900

BMH1
Protein BMH1

1

6

High-throughput

0.479

High

744518

HBS1
Elongation factor 1 alpha-like protein

1

4

High-throughput

0.479

High

750743

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

783494

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

792171

GBLP
Small ribosomal subunit protein RACK1

1

4

Small-scale

0.479

High

793341

SYG
Glycine--tRNA ligase 1, mitochondrial

1

2

High-throughput

0.479

High

795473

ATG8
Autophagy-related protein 8

1

7

High-throughput

0.479

High

802301

RS20
Small ribosomal subunit protein uS10

1

1

Small-scale

0.479

High

802577

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

802669

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.479

High

804342

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.479

High

850455

LSB3
LAS seventeen-binding protein 3

1

3

High-throughput

0.479

High

858112

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.479

High

874447

RS12
Small ribosomal subunit protein eS12

1

1

Small-scale

0.479

High

918633

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

922635

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.479

High

922676

SYC
Cysteine--tRNA ligase

1

2

High-throughput

0.479

High

922677

PDR16
Phosphatidylinositol transfer protein PDR16

1

1

High-throughput

0.479

High

922683

ELP4
Elongator complex protein 4

1

1

High-throughput

0.479

High

922693

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

8

High-throughput

0.479

High

922701

MEX67
mRNA export factor MEX67

1

3

High-throughput

0.479

High

383342

RL28
Large ribosomal subunit protein uL15

1

0

Small-scale

0.458

High

436087

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.458

High

454175

SYH
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

512127

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

558819

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

571359

CPYI
Carboxypeptidase Y inhibitor

1

0

Small-scale

0.458

High

585141

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.458

High

619171

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.458

High

674751

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.458

High

678247

BUD23
18S rRNA

1

0

High-throughput

0.458

High

687604

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

688930

RS5
Small ribosomal subunit protein uS7

1

0

Small-scale

0.458

High

758523

KTI12
Protein KTI12

1

0

High-throughput

0.458

High

816089

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

0

High-throughput

0.458

High

818549

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

835848

RL10
Large ribosomal subunit protein uL16

1

0

Small-scale

0.458

High

918008

YGD9
Putative uncharacterized oxidoreductase YGL039W

1

0

High-throughput

0.458

High

922686

YL225
Uncharacterized SVF1-like protein YLR225C

1

0

High-throughput

0.458

High

922688

SDO1
Ribosome maturation protein SDO1

1

0

High-throughput

0.458

High

626837

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.445

High

742091

HSP7F
Heat shock protein homolog SSE1

1

17

High-throughput

0.445

High

742911

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

752566

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

816336

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.445

High

922681

ULP1
Ubiquitin-like-specific protease 1

1

5

High-throughput

0.439

High

383821

RS17A
Small ribosomal subunit protein eS17A

1

2

Small-scale

0.437

High

410258

RL25
Large ribosomal subunit protein uL23

1

1

Small-scale

0.437

High

432888

RL9A
Large ribosomal subunit protein uL6A

1

2

Small-scale

0.437

High

433055

RL6B
Large ribosomal subunit protein eL6B

1

1

Small-scale

0.437

High

503411

RL11A
Large ribosomal subunit protein uL5A

1

2

Small-scale

0.437

High

511246

RL20B
Large ribosomal subunit protein eL20B

1

1

Small-scale

0.437

High

560813

SYQ
Glutamine--tRNA ligase

1

3

High-throughput

0.437

High

570287

RS17B
Small ribosomal subunit protein eS17B

1

2

Small-scale

0.437

High

601096

RL8A
Large ribosomal subunit protein eL8A

1

2

Small-scale

0.437

High

616439

SEC18
Vesicular-fusion protein SEC18

1

3

High-throughput

0.437

High

655494

RS3A2
Small ribosomal subunit protein eS1B

1

2

Small-scale

0.437

High

689580

RS7A
Small ribosomal subunit protein eS7A

1

1

Small-scale

0.437

High

707788

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

712632

RL8B
Large ribosomal subunit protein eL8B

1

2

Small-scale

0.437

High

747499

RSSA1
Small ribosomal subunit protein uS2A

1

4

Small-scale

0.437

High

753503

RS3A1
Small ribosomal subunit protein eS1A

1

2

Small-scale

0.437

High

812528

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

816123

SIT1
Siderophore iron transporter 1

1

2

High-throughput

0.437

High

825233

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.437

High

858037

RSSA2
Small ribosomal subunit protein uS2B

1

4

Small-scale

0.437

High

874330

HOSC
Homocitrate synthase, cytosolic isozyme

1

1

High-throughput

0.437

High

902658

RL9B
Large ribosomal subunit protein uL6B

1

2

Small-scale

0.437

High

922679

MAP1
Methionine aminopeptidase 1

1

1

High-throughput

0.437

High

922680

RL6A
Large ribosomal subunit protein eL6A

1

1

Small-scale

0.437

High

922682

RL21A
Large ribosomal subunit protein eL21A

1

1

Small-scale

0.437

High

922687

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

922689

ENB1
Siderophore iron transporter ENB1

1

2

High-throughput

0.437

High

922690

SGT1
Protein SGT1

1

2

High-throughput

0.437

High

922694

HOSM
Homocitrate synthase, mitochondrial

1

1

High-throughput

0.437

High

922696

DBP10
ATP-dependent RNA helicase DBP10

1

3

High-throughput

0.437

High

922699

RL21B
Large ribosomal subunit protein eL21B

1

1

Small-scale

0.437

High

922700

RL11B
Large ribosomal subunit protein uL5B

1

2

Small-scale

0.437

High

877873

VATG
V-type proton ATPase subunit G

2

0

High-throughput

0.300

High

845905

NSE4
Non-structural maintenance of chromosome element 4

2

0

High-throughput

0.295

High

506377

NFT1
ABC transporter NFT1

1

0

High-throughput

0.282

High

713507

TRXB1
Thioredoxin reductase 1

1

0

High-throughput

0.279

Low

797977

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.279

Low

836071

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

827064

GPX3
Glutathione peroxidase-like peroxiredoxin HYR1

1

0

High-throughput

0.265

Low

94577

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

506400

YK104
Putative uncharacterized protein YKR104W

1

0

High-throughput

0.251

Low

916442

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

Small-scale

0.251

Low

514168

RS16B
Small ribosomal subunit protein uS9B

1

0

Small-scale

0.249

Low

514333

RL12B
Large ribosomal subunit protein uL11B

1

0

Small-scale

0.249

Low

575559

NMT
Glycylpeptide N-tetradecanoyltransferase

1

0

High-throughput

0.249

Low

636955

CCA1
CCA tRNA nucleotidyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

780046

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

801758

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

808749

ATU2
Copper-transporting ATPase

1

0

High-throughput

0.249

Low

830085

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.249

Low

863858

RL17B
Large ribosomal subunit protein uL22B

1

0

Small-scale

0.249

Low

922691

TRMB
tRNA

1

0

High-throughput

0.249

Low

776535

NU120
Nucleoporin NUP120

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025