Protein: CALM
Calmodulin (CaM)

Gene: CALM, CMD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 176
UniProt ID: P06787

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000226 - microtubule cytoskeleton organization
GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449178

MYO5
Myosin-5

8

19

Small-scale

0.977

High

449089

SP110
Spindle pole body component 110

11

4

Small-scale

0.976

High

449063

MYO2
Myosin-2

7

11

Small-scale

0.973

High

449080

KCC1
Calcium/calmodulin-dependent protein kinase I

8

20

Small-scale

0.969

High

449071

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

8

18

Small-scale

0.968

High

449068

KCC2
Calcium/calmodulin-dependent protein kinase II

6

20

Small-scale

0.950

High

449049

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

6

18

Small-scale

0.947

High

449111

MYO3
Myosin-3

4

20

Small-scale

0.890

High

449094

MYO4
Myosin-4

3

11

Small-scale

0.870

High

449153

MLC1
Myosin light chain 1

3

14

High-throughput

0.867

High

449197

IQG1
Ras GTPase-activating-like protein IQG1

3

15

Small-scale

0.822

High

449074

CANB
Calcineurin subunit B

2

19

High-throughput

0.776

High

449100

SWE1
Mitosis inhibitor protein kinase SWE1

1

4

High-throughput

0.691

High

449134

PRK1
Actin-regulating kinase PRK1

1

12

High-throughput

0.691

High

449158

ARPC2
Actin-related protein 2/3 complex subunit 2

3

2

Small-scale

0.682

High

449075

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

13

High-throughput

0.665

High

449151

YGZ2
Ankyrin repeat-containing protein YGL242C

1

2

High-throughput

0.665

High

449133

MLP2
Protein MLP2

3

1

Small-scale

0.650

High

449057

PHO85
Cyclin-dependent protein kinase PHO85

1

10

High-throughput

0.647

High

449168

KIN4
Serine/threonine-protein kinase KIN4

1

12

High-throughput

0.647

High

449163

ACT
Actin

1

1

High-throughput

0.646

High

449113

SPC42
Spindle pole body component SPC42

3

0

Small-scale

0.623

High

449050

CYPH
Peptidyl-prolyl cis-trans isomerase

2

4

High-throughput

0.621

High

449162

MPS1
Serine/threonine-protein kinase MPS1

1

5

High-throughput

0.618

High

445298

CDC31
Cell division control protein 31

1

15

High-throughput

0.618

High

449093

HOG1
Mitogen-activated protein kinase HOG1

1

7

Small-scale

0.618

High

449097

FIMB
Fimbrin

1

1

Small-scale

0.618

High

449145

ARP3
Actin-related protein 3

1

2

Small-scale

0.618

High

366748

IPYR
Inorganic pyrophosphatase

2

0

Small-scale

0.612

High

449160

CNM67
Chaotic nuclear migration protein 67

2

2

Small-scale

0.602

High

449118

SHE3
SWI5-dependent HO expression protein 3

2

0

High-throughput

0.595

High

449082

BMH1
Protein BMH1

2

5

High-throughput

0.594

High

449189

VPS13
Intermembrane lipid transfer protein VPS13

3

7

High-throughput

0.593

High

449120

RS20
Small ribosomal subunit protein uS10

2

1

Small-scale

0.584

High

449102

SPC29
Spindle pole component 29

2

0

Small-scale

0.577

High

449092

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

4

High-throughput

0.575

High

449141

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

2

Small-scale

0.570

High

449070

HSP12
12 kDa heat shock protein

2

0

High-throughput

0.563

High

449128

RV167
Reduced viability upon starvation protein 167

1

8

Small-scale

0.561

High

449140

VTC2
Vacuolar transporter chaperone complex subunit 2

1

2

Small-scale

0.561

High

449144

VTC4
Vacuolar transporter chaperone complex subunit 4

1

2

Small-scale

0.561

High

449171

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

2

Small-scale

0.561

High

449187

ASR1
Alcohol-sensitive RING finger protein 1

1

0

Small-scale

0.554

High

449062

CSK22
Casein kinase II subunit alpha'

1

20

Small-scale

0.553

High

449179

EUC1
Transcription factor-like protein EUC1

2

0

High-throughput

0.551

High

449058

TPM1
Tropomyosin-1

1

0

Small-scale

0.537

High

449084

P5CR
Pyrroline-5-carboxylate reductase

1

0

Small-scale

0.537

High

449175

OYE2
NADPH dehydrogenase 2

1

0

Small-scale

0.537

High

449191

MCA1
Metacaspase-1

1

0

Small-scale

0.537

High

449043

SYV
Valine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

449065

PWP1
Periodic tryptophan protein 1

1

1

High-throughput

0.536

High

449072

IF5A1
Eukaryotic translation initiation factor 5A-1

1

1

High-throughput

0.536

High

449104

EDE1
EH domain-containing and endocytosis protein 1

1

2

High-throughput

0.536

High

449115

PGM2
Phosphoglucomutase 2

1

1

High-throughput

0.536

High

449119

MSG5
Tyrosine-protein phosphatase MSG5

1

2

High-throughput

0.536

High

449152

HUL5
E3 ubiquitin-protein ligase HUL5

1

13

High-throughput

0.536

High

449172

COFI
Cofilin

1

3

High-throughput

0.536

High

449056

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

9

High-throughput

0.515

High

449125

RGA1
Rho-type GTPase-activating protein 1

1

7

High-throughput

0.515

High

449130

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

3

High-throughput

0.515

High

449182

YM94
Uncharacterized protein YMR315W

1

1

High-throughput

0.515

High

449200

GST2
Glutathione S-transferase 2

1

1

High-throughput

0.515

High

449067

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.513

High

449083

MCM5
Minichromosome maintenance protein 5

1

0

High-throughput

0.513

High

449149

SHE4
SWI5-dependent HO expression protein 4

1

0

High-throughput

0.513

High

449159

HCH1
Hsp90 co-chaperone HCH1

1

0

High-throughput

0.513

High

449199

PST2
Protoplast secreted protein 2

1

0

High-throughput

0.513

High

428014

PLMT
Phosphatidyl-N-methylethanolamine N-methyltransferase

1

1

Small-scale

0.512

High

449088

PSA5
Proteasome subunit alpha type-5

1

1

Small-scale

0.512

High

449116

GLU2A
Glucosidase 2 subunit alpha

1

1

Small-scale

0.512

High

449155

RL26B
Large ribosomal subunit protein uL24B

1

1

Small-scale

0.512

High

449169

HAP5
Transcriptional activator HAP5

1

1

Small-scale

0.512

High

449129

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

High-throughput

0.501

High

449137

BNI1
Protein BNI1

1

4

High-throughput

0.501

High

394105

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.500

High

449052

HSP26
Heat shock protein 26

1

3

High-throughput

0.500

High

449053

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.500

High

449066

CLH
Clathrin heavy chain

1

1

High-throughput

0.500

High

449107

BMH2
Protein BMH2

1

5

High-throughput

0.500

High

449098

RAD23
UV excision repair protein RAD23

1

0

High-throughput

0.493

High

449108

TREB
Probable trehalase

1

0

High-throughput

0.493

High

449044

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.489

High

449109

SPT7
SAGA complex subunit SPT7

1

1

High-throughput

0.489

High

449112

NDK
Nucleoside diphosphate kinase

1

1

High-throughput

0.489

High

449174

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.489

High

449139

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

416337

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

449042

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.479

High

434690

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

449078

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

449110

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.479

High

449132

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

Small-scale

0.479

High

449147

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

449166

NOP3
Serine/arginine

1

1

High-throughput

0.479

High

449173

TOM1
E3 ubiquitin-protein ligase TOM1

1

8

High-throughput

0.479

High

449181

DCE
Glutamate decarboxylase

1

1

Small-scale

0.479

High

449188

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

449193

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

449201

LAS17
Proline-rich protein LAS17

1

9

Small-scale

0.479

High

449086

PYC2
Pyruvate carboxylase 2

1

1

High-throughput

0.470

High

449164

H3
Histone H3

1

2

High-throughput

0.470

High

149484

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

438557

SC160
Protein SCP160

1

0

High-throughput

0.458

High

449076

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

449106

KTI12
Protein KTI12

1

0

Small-scale

0.458

High

449121

SPC97
Spindle pole body component SPC97

1

0

Small-scale

0.458

High

449124

CSK2C
Casein kinase II subunit beta'

1

0

Small-scale

0.458

High

449126

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

449131

PXP1
2-hydroxyacyl-CoA lyase

1

0

High-throughput

0.458

High

449146

HGH1
Protein HGH1

1

0

Small-scale

0.458

High

449156

TBG
Tubulin gamma chain

1

0

Small-scale

0.458

High

449167

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

449177

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

449195

MRH1
Protein MRH1

1

0

High-throughput

0.458

High

449143

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

2

High-throughput

0.457

High

366878

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.457

High

449059

ADT2
ADP,ATP carrier protein 2

1

2

High-throughput

0.457

High

449047

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

449077

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

449079

BUB2
Mitotic check point protein BUB2

1

3

High-throughput

0.445

High

449096

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

449165

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.445

High

401814

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.437

High

433343

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

441599

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

449045

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

449055

HEMH
Ferrochelatase, mitochondrial

1

3

High-throughput

0.437

High

449122

SET5
Histone-lysine N-methyltransferase SET5

1

0

High-throughput

0.426

High

449073

SIS1
Protein SIS1

1

2

High-throughput

0.407

High

361406

SODC
Superoxide dismutase [Cu-Zn]

2

0

High-throughput

0.324

High

449051

MET8
Siroheme biosynthesis protein MET8 [Includes: Precorrin-2 dehydrogenase

1

0

Small-scale

0.292

High

449054

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.292

High

449060

DAP2
Dipeptidyl aminopeptidase B

1

0

Small-scale

0.292

High

449085

THI4
Thiamine thiazole synthase

1

0

Small-scale

0.292

High

449091

AUA1
Ammonia regulation of amino acid uptake protein

1

0

Small-scale

0.292

High

449095

SPS19
Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing]

1

0

Small-scale

0.292

High

449099

SRPR
Signal recognition particle receptor subunit alpha homolog

1

0

Small-scale

0.292

High

449105

ZRT3
Zinc-regulated transporter 3

1

0

Small-scale

0.292

High

449114

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

Small-scale

0.292

High

449117

REG2
Protein REG2

1

0

Small-scale

0.292

High

449127

YAN4
Uncharacterized protein YAR064W

1

0

Small-scale

0.292

High

449136

MSH4
MutS protein homolog 4

1

0

Small-scale

0.292

High

449138

REF2
RNA end formation protein 2

1

0

Small-scale

0.292

High

449150

SAP4
SIT4-associating protein SAP4

1

0

Small-scale

0.292

High

449154

PUS2
tRNA pseudouridine(27/28) synthase

1

0

Small-scale

0.292

High

449157

SUN4
Probable secreted beta-glucosidase SUN4

1

0

Small-scale

0.292

High

449176

ROT1
Protein ROT1

1

0

Small-scale

0.292

High

449183

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

Small-scale

0.292

High

449184

ECM7
Protein ECM7

1

0

Small-scale

0.292

High

449202

FRE6
Ferric reductase transmembrane component 6

1

0

Small-scale

0.292

High

449061

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.269

Low

449087

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.269

Low

449090

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.269

Low

449170

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.269

Low

449180

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.269

Low

449185

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.269

Low

449190

ZEO1
Protein ZEO1

1

0

High-throughput

0.269

Low

449069

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.261

Low

449101

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

449186

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.261

Low

449198

YVC1
Calcium channel YVC1

1

0

Small-scale

0.261

Low

368542

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

449048

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

449064

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.261

Low

449142

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

449046

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

449081

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

449103

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

449135

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

449161

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

449192

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.249

Low

449196

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

449203

YM094
Putative uncharacterized protein YML094C-A

1

0

High-throughput

0.238

Low

449123

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

449148

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.232

Low

449194

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025