Protein: VPS15
Serine/threonine-protein kinase VPS15 (EC 2.7.11.1) (Golgi-retention defective mutant protein 8) (Vacuolar protein sorting-associated protein 15)

Gene: VPS15
Organism: Saccharomyces cerevisiae S288C
Interactions: 79
UniProt ID: P22219

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0000139 - Golgi membrane
GO:0000329 - fungal-type vacuole membrane
GO:0000425 - pexophagy
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

606232

VPS34
Phosphatidylinositol 3-kinase VPS34

7

11

Small-scale

0.750

High

606252

PP2C3
Protein phosphatase 2C homolog 3

2

20

High-throughput

0.717

High

606288

BECN1
Vacuolar protein sorting-associated protein 30

5

4

Small-scale

0.709

High

606263

ATG14
Autophagy-related protein 14

6

0

Small-scale

0.697

High

606293

VPS38
Vacuolar protein sorting-associated protein 38

5

0

Small-scale

0.685

High

606281

ATG1
Serine/threonine-protein kinase ATG1

1

17

Small-scale

0.647

High

440232

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

2

3

Small-scale

0.634

High

350846

YPT1
GTP-binding protein YPT1

1

4

High-throughput

0.618

High

429172

SEC4
Ras-related protein SEC4

1

4

High-throughput

0.618

High

606231

VPS15
Serine/threonine-protein kinase VPS15

1

19

High-throughput

0.618

High

606235

KC11
Casein kinase I homolog 1

1

18

High-throughput

0.618

High

606250

YPT7
Ypt/Rab-type GTPase YPT7

1

7

High-throughput

0.618

High

606255

VPS21
Vacuolar protein sorting-associated protein 21

1

12

High-throughput

0.618

High

606256

YPT52
GTP-binding protein YPT52

1

11

High-throughput

0.618

High

606264

YPT31
GTP-binding protein YPT31/YPT8

1

4

High-throughput

0.618

High

606268

AKR1
Palmitoyltransferase AKR1

1

3

High-throughput

0.618

High

606272

KC13
Casein kinase I homolog 3

1

18

High-throughput

0.618

High

606292

ATG38
Autophagy-related protein 38

2

0

Small-scale

0.606

High

477131

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

11

Small-scale

0.579

High

456989

SWI6
Regulatory protein SWI6

1

8

High-throughput

0.553

High

606275

DAK2
Dihydroxyacetone kinase 2

1

0

High-throughput

0.518

High

530054

ATC1
Calcium-transporting ATPase 1

1

3

High-throughput

0.479

High

599418

VPS1
Vacuolar protein sorting-associated protein 1

1

3

High-throughput

0.479

High

606233

BET1
Protein transport protein BET1

1

3

High-throughput

0.479

High

606238

CDC48
Cell division control protein 48

1

8

High-throughput

0.479

High

606239

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

606241

COPG
Coatomer subunit gamma

1

6

High-throughput

0.479

High

606245

ATC5
Phospholipid-transporting ATPase DNF1

1

1

High-throughput

0.479

High

606246

EMP24
Endosomal protein P24B

1

1

High-throughput

0.479

High

606247

PEP12
Syntaxin PEP12

1

5

High-throughput

0.479

High

606248

SSO1
Protein SSO1

1

4

High-throughput

0.479

High

606253

CASP
Protein CASP

1

14

High-throughput

0.479

High

606257

DID4
DOA4-independent degradation protein 4

1

1

High-throughput

0.479

High

606260

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

2

High-throughput

0.479

High

606261

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

4

High-throughput

0.479

High

606266

GOSR1
Golgi SNAP receptor complex member 1

1

1

High-throughput

0.479

High

606270

SNF7
Vacuolar-sorting protein SNF7

1

2

High-throughput

0.479

High

606273

VAC8
Vacuolar protein 8

1

7

High-throughput

0.479

High

606274

ATC7
Phospholipid-transporting ATPase NEO1

1

3

High-throughput

0.479

High

606284

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.479

High

606285

DID2
Vacuolar protein-sorting-associated protein 46

1

1

High-throughput

0.479

High

606289

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.479

High

606269

RV167
Reduced viability upon starvation protein 167

1

4

High-throughput

0.470

High

546688

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.458

High

605816

SEC22
Protein transport protein SEC22

1

0

High-throughput

0.458

High

606242

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

0

High-throughput

0.458

High

606244

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.458

High

606259

TVP38
Golgi apparatus membrane protein TVP38

1

0

High-throughput

0.458

High

606262

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.458

High

606265

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.458

High

606267

SVP26
Protein SVP26

1

0

High-throughput

0.458

High

606276

EMP47
Protein EMP47

1

0

High-throughput

0.458

High

606277

SFT1
Protein transport protein SFT1

1

0

High-throughput

0.458

High

606282

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

606283

PRA1
Prenylated Rab acceptor 1

1

0

High-throughput

0.458

High

606290

VTI1
t-SNARE VTI1

1

0

High-throughput

0.458

High

606297

YOP1
Protein YOP1

1

0

High-throughput

0.458

High

606287

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.457

High

510287

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

606243

HSP7F
Heat shock protein homolog SSE1

1

17

High-throughput

0.445

High

606251

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

561108

CDC23
Anaphase-promoting complex subunit CDC23

1

1

High-throughput

0.437

High

606254

SEG2
Eisosome protein SEG2

1

1

High-throughput

0.437

High

606278

RSF2
Respiration factor 2

1

1

High-throughput

0.437

High

606279

BUL1
Ubiquitin ligase-binding protein BUL1

1

1

High-throughput

0.437

High

606280

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

10

High-throughput

0.437

High

606286

CTF4
DNA polymerase alpha-binding protein

1

2

High-throughput

0.437

High

606291

APC4
Anaphase-promoting complex subunit 4

1

1

High-throughput

0.437

High

606234

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.249

Low

606236

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.249

Low

606237

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.249

Low

606240

RIF1
Telomere length regulator protein RIF1

1

0

High-throughput

0.249

Low

606249

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

606258

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.249

Low

606271

SS120
Protein SSP120

1

0

High-throughput

0.249

Low

606294

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.249

Low

606295

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.249

Low

606296

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024