Protein: RPOD
RNA polymerase sigma factor RpoD (Sigma-70)

Gene: RPOD
Organism: Escherichia coli K-12
Interactions: 59
UniProt ID: P00579

Gene Ontology (top 5):
GO:0000345 - cytosolic DNA-directed RNA polymerase complex
GO:0003677 - DNA binding
GO:0005829 - cytosol
GO:0006352 - DNA-templated transcription initiation
GO:0009408 - response to heat

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

365827

RSD
Regulator of sigma D

9

2

Small-scale

0.973

High

365815

RPOB
DNA-directed RNA polymerase subunit beta

5

12

Small-scale

0.919

High

365814

RPOC
DNA-directed RNA polymerase subunit beta'

4

7

Small-scale

0.903

High

365798

ADA
Bifunctional transcriptional activator/DNA repair enzyme Ada

3

0

Small-scale

0.823

High

365822

MELR
Melibiose operon regulatory protein

2

8

Small-scale

0.795

High

365811

RPOA
DNA-directed RNA polymerase subunit alpha

2

4

High-throughput

0.789

High

365794

RPOD
RNA polymerase sigma factor RpoD

2

8

Small-scale

0.785

High

365799

RHAS
HTH-type transcriptional activator RhaS

3

8

Small-scale

0.760

High

365800

RHAR
HTH-type transcriptional activator RhaR

2

8

Small-scale

0.709

High

365818

ARAC
Arabinose operon regulatory protein

1

8

High-throughput

0.698

High

365823

CRP
DNA-binding transcriptional dual regulator CRP

1

3

High-throughput

0.698

High

365833

CHBR
HTH-type transcriptional regulator ChbR

1

0

High-throughput

0.663

High

365828

RHO
Transcription termination factor Rho

3

1

High-throughput

0.657

High

365841

RL4
Large ribosomal subunit protein uL4

3

0

High-throughput

0.629

High

365851

YPDC
Uncharacterized HTH-type transcriptional regulator YpdC

1

8

High-throughput

0.625

High

365837

GADX
HTH-type transcriptional regulator GadX

1

8

High-throughput

0.618

High

365819

FNR
Fumarate and nitrate reduction regulatory protein

1

3

Small-scale

0.618

High

365801

IF2
Translation initiation factor IF-2

2

3

High-throughput

0.588

High

365803

RL7
Large ribosomal subunit protein bL12

2

1

High-throughput

0.588

High

365805

RL1
Large ribosomal subunit protein uL1

2

1

High-throughput

0.588

High

365795

RS6
Small ribosomal subunit protein bS6

2

0

High-throughput

0.585

High

365836

PEPB
Peptidase B

2

0

High-throughput

0.585

High

365807

RS2
Small ribosomal subunit protein uS2

2

1

High-throughput

0.574

High

365804

RL19
Large ribosomal subunit protein bL19

2

0

High-throughput

0.563

High

365806

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.563

High

365813

TMAR
Pole-localizer protein TmaR

2

0

High-throughput

0.563

High

365817

G3P1
Glyceraldehyde-3-phosphate dehydrogenase A

2

0

High-throughput

0.563

High

365829

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.563

High

365824

CEDA
Cell division activator CedA

1

0

High-throughput

0.523

High

365802

LEXA
LexA repressor

1

0

High-throughput

0.518

High

365839

RAPA
RNA polymerase-associated protein RapA

1

0

High-throughput

0.518

High

365796

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

365810

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

365821

DNAG
DNA primase

1

0

High-throughput

0.513

High

365834

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

365835

MFD
Transcription-repair-coupling factor

1

0

High-throughput

0.513

High

365843

RL5
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

365844

GMHBB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

1

0

High-throughput

0.513

High

365849

HXPB
Hexitol phosphatase B

1

0

High-throughput

0.513

High

365832

EFTU1
Elongation factor Tu 1

1

1

High-throughput

0.489

High

365808

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.484

High

365809

RS4
Small ribosomal subunit protein uS4

1

1

High-throughput

0.484

High

365825

NUSA
Transcription termination/antitermination protein NusA

1

1

High-throughput

0.484

High

365840

RL2
Large ribosomal subunit protein uL2

1

1

High-throughput

0.484

High

365846

KDGR
HTH-type transcriptional regulator KdgR

1

1

High-throughput

0.479

High

365812

RPOZ
DNA-directed RNA polymerase subunit omega

1

0

High-throughput

0.464

High

365820

ACCA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

1

0

High-throughput

0.464

High

365842

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

365845

INSN1
Putative transposase InsN for insertion sequence element IS911A

1

0

High-throughput

0.438

High

365826

POTD
Spermidine/putrescine-binding periplasmic protein

2

0

High-throughput

0.318

High

365830

RS1
Small ribosomal subunit protein bS1

2

0

High-throughput

0.307

High

365831

SECE
Protein translocase subunit SecE

1

0

High-throughput

0.282

High

365838

IDNK
Thermosensitive gluconokinase

1

0

High-throughput

0.282

High

365797

RL15
Large ribosomal subunit protein uL15

1

0

High-throughput

0.279

Low

365816

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.279

Low

365848

ECPB
Probable fimbrial chaperone EcpB

1

0

High-throughput

0.279

Low

365850

HSCC
Chaperone protein HscC

1

0

Small-scale

0.249

Low

365847

A2MGH
Putative alpha-2-macroglobulin homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025