Protein: MPH1
ATP-dependent DNA helicase MPH1 (EC 3.6.4.12) (FANCM-like protein 1) (Mutator phenotype protein 1)

Gene: MPH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 103
UniProt ID: P40562

Gene Ontology (top 5):
GO:0000400 - four-way junction DNA binding
GO:0000725 - recombinational repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0007535 - donor selection

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607287

RFA1
Replication factor A protein 1

8

10

Small-scale

0.747

High

775585

SMC5
Structural maintenance of chromosomes protein 5

6

11

Small-scale

0.742

High

774179

FKH1
Fork head protein homolog 1

4

9

Small-scale

0.701

High

775565

YG1T
Uncharacterized protein YGR042W

5

0

Small-scale

0.683

High

775573

MSH6
DNA mismatch repair protein MSH6

3

3

High-throughput

0.662

High

697832

MG101
Mitochondrial genome maintenance protein MGM101

4

0

Small-scale

0.649

High

593536

DBP3
ATP-dependent RNA helicase DBP3

1

17

Small-scale

0.621

High

356528

H4
Histone H4

1

8

High-throughput

0.618

High

603317

SNF2
Transcription regulatory protein SNF2

1

18

High-throughput

0.618

High

715642

SGS1
ATP-dependent helicase SGS1

1

18

High-throughput

0.618

High

775563

INO80
Chromatin-remodeling ATPase INO80

1

20

High-throughput

0.618

High

491485

HSP71
Heat shock protein SSA1

2

8

High-throughput

0.611

High

419621

RAD52
DNA repair and recombination protein RAD52

2

0

Small-scale

0.559

High

644762

RFA2
Replication factor A protein 2

2

13

Small-scale

0.533

High

775596

SMC6
Structural maintenance of chromosomes protein 6

1

11

Small-scale

0.515

High

604300

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.513

High

767100

KRE29
DNA repair protein KRE29

1

0

Small-scale

0.493

High

389399

HXKB
Hexokinase-2

1

1

Small-scale

0.481

High

514256

NHP6B
Non-histone chromosomal protein 6B

1

20

Small-scale

0.481

High

523401

SRS2
ATP-dependent DNA helicase SRS2

1

3

Small-scale

0.481

High

540592

CYPH
Peptidyl-prolyl cis-trans isomerase

1

11

Small-scale

0.481

High

550059

CSK21
Casein kinase II subunit alpha

1

12

Small-scale

0.481

High

560458

PDC5
Pyruvate decarboxylase isozyme 2

1

1

Small-scale

0.481

High

608704

UBA1
Ubiquitin-activating enzyme E1 1

1

2

Small-scale

0.481

High

613817

TKT1
Transketolase 1

1

3

Small-scale

0.481

High

775570

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

7

High-throughput

0.481

High

775588

NCBP2
Nuclear cap-binding protein subunit 2

1

17

Small-scale

0.481

High

775590

ELG1
Telomere length regulation protein ELG1

1

2

Small-scale

0.481

High

355515

H2B1
Histone H2B.1

1

7

High-throughput

0.479

High

355914

H2B2
Histone H2B.2

1

7

High-throughput

0.479

High

388109

TOP1
DNA topoisomerase 1

1

6

High-throughput

0.479

High

425419

PIF1
ATP-dependent DNA helicase PIF1

1

2

High-throughput

0.479

High

443938

CYAA
Adenylate cyclase

1

2

High-throughput

0.479

High

602357

DPOE
DNA polymerase epsilon catalytic subunit A

1

2

High-throughput

0.479

High

629338

MSH3
DNA mismatch repair protein MSH3

1

3

High-throughput

0.479

High

639272

MSH2
DNA mismatch repair protein MSH2

1

3

High-throughput

0.479

High

662463

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

688649

MCM10
Minichromosome maintenance protein 10

1

1

High-throughput

0.479

High

696151

SWI3
SWI/SNF complex subunit SWI3

1

5

High-throughput

0.479

High

698838

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

4

High-throughput

0.479

High

751316

RFC1
Replication factor C subunit 1

1

1

High-throughput

0.479

High

762075

FHL1
Pre-rRNA-processing protein FHL1

1

13

High-throughput

0.479

High

775559

FKH2
Fork head protein homolog 2

1

11

High-throughput

0.479

High

775560

CHA4
Activatory protein CHA4

1

3

High-throughput

0.479

High

775566

YG5B
Uncharacterized RNA-binding protein YGR250C

1

8

High-throughput

0.479

High

775569

CDC14
Tyrosine-protein phosphatase CDC14

1

9

Small-scale

0.479

High

775571

PDR12
ATP-dependent permease PDR12

1

1

High-throughput

0.479

High

775577

TRI1
Protein TRI1

1

1

High-throughput

0.479

High

775578

ARP9
Actin-like protein ARP9

1

7

High-throughput

0.479

High

775591

CFT2
Cleavage factor two protein 2

1

3

High-throughput

0.479

High

775595

CMR1
DNA damage-binding protein CMR1

1

13

High-throughput

0.479

High

733346

SPO14
Phospholipase D1

1

0

High-throughput

0.460

High

501292

PCKA
Phosphoenolpyruvate carboxykinase

1

0

High-throughput

0.458

High

612171

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.458

High

710658

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.458

High

767464

DOT6
Transcriptional regulatory protein DOT6

1

0

High-throughput

0.458

High

775564

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.458

High

775582

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.458

High

775592

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

775593

IES3
Ino eighty subunit 3

1

0

High-throughput

0.458

High

366426

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

494179

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

511626

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

694868

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

705277

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

406226

RL29
Large ribosomal subunit protein eL29

1

1

Small-scale

0.439

High

758067

BFR1
Nuclear segregation protein BFR1

1

1

Small-scale

0.439

High

767371

UTP7
U3 small nucleolar RNA-associated protein 7

1

14

Small-scale

0.439

High

532787

ACOX
Acyl-coenzyme A oxidase

1

5

High-throughput

0.437

High

634646

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

698237

CACP
Carnitine O-acetyltransferase, mitochondrial

1

4

High-throughput

0.437

High

704100

SFC1
Succinate/fumarate mitochondrial transporter

1

7

High-throughput

0.437

High

756510

KOG1
Target of rapamycin complex 1 subunit KOG1

1

9

High-throughput

0.437

High

766903

YAT2
Carnitine O-acetyltransferase YAT2

1

4

High-throughput

0.437

High

775568

CACM
Putative mitochondrial carnitine O-acetyltransferase

1

4

High-throughput

0.437

High

775575

TMA64
Translation machinery-associated protein 64

1

1

High-throughput

0.437

High

775579

FCF1
rRNA-processing protein FCF1

1

1

High-throughput

0.437

High

775581

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

20

High-throughput

0.437

High

775583

REH1
Cytoplasmic 60S subunit biogenesis factor REH1

1

2

High-throughput

0.437

High

775586

RTC1
Restriction of telomere capping protein 1

1

11

High-throughput

0.437

High

775587

FDH1
Formate dehydrogenase 1

1

3

High-throughput

0.437

High

689894

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

775597

CENPX
Inner kinetochore subunit MHF2

5

0

Small-scale

0.370

High

775598

CENPS
Inner kinetochore subunit MHF1

4

0

Small-scale

0.367

High

689795

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

3

0

Small-scale

0.334

High

644806

RFA3
Replication factor A protein 3

2

0

Small-scale

0.305

High

558638

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

Small-scale

0.251

Low

733844

RPF2
Ribosome biogenesis protein RPF2

1

0

Small-scale

0.251

Low

757389

IF1A
Eukaryotic translation initiation factor 1A

1

0

Small-scale

0.251

Low

775561

CSK2B
Casein kinase II subunit beta

1

0

Small-scale

0.251

Low

775572

COFI
Cofilin

1

0

Small-scale

0.251

Low

775576

ECM18
Protein ECM18

1

0

Small-scale

0.251

Low

634354

LRE1
Laminarase-resistance protein LRE1

1

0

High-throughput

0.249

Low

704484

DHE2
NAD-specific glutamate dehydrogenase

1

0

High-throughput

0.249

Low

772496

ATF1
Alcohol O-acetyltransferase 1

1

0

High-throughput

0.249

Low

772715

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.249

Low

775562

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.249

Low

775567

VAC7
Vacuolar segregation protein 7

1

0

High-throughput

0.249

Low

775580

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.249

Low

775584

SSK1
Osmolarity two-component system protein SSK1

1

0

High-throughput

0.249

Low

775589

AIM41
Altered inheritance of mitochondria protein 41, mitochondrial

1

0

High-throughput

0.249

Low

775594

YD041
Putative uncharacterized protein YDL041W

1

0

High-throughput

0.238

Low

775574

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024