Protein: LEC1
PX domain-containing protein LEC1 (Lipid-droplet ergosterol cortex protein 1)

Gene: LEC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: Q06839

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005789 - endoplasmic reticulum membrane
GO:0005811 - lipid droplet
GO:0035091 - phosphatidylinositol binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850490

LSB3
LAS seventeen-binding protein 3

1

0

High-throughput

0.518

High

757617

TGL1
Sterol esterase TGL1

1

1

Small-scale

0.481

High

1057312

YEH1
Sterol esterase 1

1

1

Small-scale

0.481

High

595006

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

Small-scale

0.460

High

668962

ERG6
Sterol 24-C-methyltransferase ERG6

1

0

Small-scale

0.460

High

692634

NSR1
Nuclear localization sequence-binding protein

1

0

Small-scale

0.460

High

702314

MGLL
Monoglyceride lipase

1

0

Small-scale

0.460

High

704137

YIM1
Protein YIM1

1

0

Small-scale

0.460

High

738130

AEP1
ATPase expression protein 1, mitochondrial

1

0

Small-scale

0.460

High

755181

GCN1
eIF-2-alpha kinase activator GCN1

1

0

Small-scale

0.460

High

763676

RER2
Dehydrodolichyl diphosphate synthase complex subunit RER2

1

0

Small-scale

0.460

High

782041

PET10
Protein PET10

1

0

Small-scale

0.460

High

794139

LDH1
Lipid droplet hydrolase 1

1

0

Small-scale

0.460

High

796237

FAT1
Very long-chain fatty acid transport protein

1

0

Small-scale

0.460

High

797564

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

Small-scale

0.460

High

800450

ERG7
Lanosterol synthase ERG7

1

0

Small-scale

0.460

High

806106

MPC2
Mitochondrial pyruvate carrier 2

1

0

Small-scale

0.460

High

825122

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

0

Small-scale

0.460

High

868451

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

Small-scale

0.460

High

917974

ERV14
ER-derived vesicles protein ERV14

1

0

Small-scale

0.460

High

919654

SAY1
Steryl acetyl hydrolase 1

1

0

Small-scale

0.460

High

924018

PDR16
Phosphatidylinositol transfer protein PDR16

1

0

Small-scale

0.460

High

1010407

TOM5
Mitochondrial import receptor subunit TOM5

1

0

Small-scale

0.460

High

1038501

PT117
Protein PET117, mitochondrial

1

0

Small-scale

0.460

High

1038504

PT191
Mitochondrial protein PET191

1

0

Small-scale

0.460

High

1050086

RTN1
Reticulon-like protein 1

1

0

Small-scale

0.460

High

1057314

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

0

Small-scale

0.460

High

1057318

YOP1
Protein YOP1

1

0

Small-scale

0.460

High

1057320

SEY1
Protein SEY1

1

0

Small-scale

0.460

High

361014

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.458

High

576076

AROF
Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited

1

0

High-throughput

0.458

High

866293

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

1057316

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

825146

QDR2
Quinidine resistance protein 2

1

1

Small-scale

0.439

High

394937

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

592524

VATB
V-type proton ATPase subunit B

2

0

High-throughput

0.298

High

366842

IPYR
Inorganic pyrophosphatase

1

0

Small-scale

0.251

Low

509930

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

0

Small-scale

0.251

Low

509974

YHU3
Uncharacterized protein YHR213W

1

0

Small-scale

0.251

Low

533536

SNF3
Low glucose sensor SNF3

1

0

Small-scale

0.251

Low

571856

SNA3
Protein SNA3

1

0

Small-scale

0.251

Low

604562

PHO81
Phosphate system positive regulatory protein PHO81

1

0

Small-scale

0.251

Low

713308

MCM5
Minichromosome maintenance protein 5

1

0

Small-scale

0.251

Low

764015

SPT10
Protein SPT10

1

0

Small-scale

0.251

Low

795848

YBC8
UPF0642 protein YBL028C

1

0

Small-scale

0.251

Low

797695

NTC20
Pre-mRNA-splicing factor NTC20

1

0

Small-scale

0.251

Low

815111

SS120
Protein SSP120

1

0

Small-scale

0.251

Low

825981

GVP36
Protein GVP36

1

0

Small-scale

0.251

Low

835529

AZF1
Transcription factor AZF1

1

0

Small-scale

0.251

Low

844175

AAD14
Putative aryl-alcohol dehydrogenase AAD14

1

0

Small-scale

0.251

Low

864708

AP3S
AP-3 complex subunit sigma

1

0

Small-scale

0.251

Low

923728

COS1
Protein COS1

1

0

Small-scale

0.251

Low

932302

ZDS2
Protein ZDS2

1

0

Small-scale

0.251

Low

1018197

PMP3
Plasma membrane proteolipid 3

1

0

Small-scale

0.251

Low

1053593

RPN7
26S proteasome regulatory subunit RPN7

1

0

Small-scale

0.251

Low

1054063

YL326
Uncharacterized membrane protein YLR326W

1

0

Small-scale

0.251

Low

1057313

YL067
Y' element ATP-dependent helicase YLL067C

1

0

Small-scale

0.251

Low

1057315

RFM1
Repression factor of MSEs protein 1

1

0

Small-scale

0.251

Low

1057317

BMT6
25S rRNA

1

0

Small-scale

0.251

Low

1057319

RRT15
Regulator of rDNA transcription protein 15

1

0

Small-scale

0.251

Low

435390

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

585514

KCY
Uridylate kinase

1

0

High-throughput

0.249

Low

708316

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

748557

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

762930

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

0

High-throughput

0.249

Low

778556

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

793064

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

793633

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

795736

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.249

Low

815802

GDI1
Rab GDP-dissociation inhibitor

1

0

High-throughput

0.249

Low

1044779

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

365201

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

671723

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025