Protein: COX15
Heme A synthase COX15 (HAS) (EC 1.17.99.9) (Cytochrome c oxidase assembly protein COX15)

Gene: COX15
Organism: Saccharomyces cerevisiae S288C
Interactions: 43
UniProt ID: P40086

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006784 - heme A biosynthetic process
GO:0016653 - oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

818401

COX15
Heme A synthase COX15

3

1

Small-scale

0.817

High

818407

SHY1
Cytochrome oxidase assembly protein SHY1

2

1

Small-scale

0.611

High

453158

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

2

2

Small-scale

0.584

High

781387

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.559

High

818409

PT117
Protein PET117, mitochondrial

2

0

Small-scale

0.559

High

579481

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

639428

COX10
Protoheme IX farnesyltransferase, mitochondrial

1

1

Small-scale

0.479

High

785927

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

815679

OXA1
Mitochondrial inner membrane protein OXA1

1

1

High-throughput

0.479

High

360791

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

Small-scale

0.458

High

399843

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

510533

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

638913

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.458

High

679739

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

734554

MSS51
Protein MSS51, mitochondrial

1

0

High-throughput

0.458

High

735504

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.458

High

736261

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

745236

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

0

Small-scale

0.458

High

746849

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

783856

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.458

High

784100

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

797624

MBA1
Inner membrane mitoribosome receptor MBA1, mitochondrial

1

0

High-throughput

0.458

High

818402

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

818403

COA1
Cytochrome c oxidase assembly factor 1

1

0

Small-scale

0.458

High

818404

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

818408

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

818410

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

818411

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.458

High

818413

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

1

0

Small-scale

0.458

High

574585

YAK1
Dual specificity protein kinase YAK1

1

1

High-throughput

0.457

High

526814

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

801055

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.426

High

818406

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

524096

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

531759

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.407

High

818405

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.407

High

557719

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.251

Low

810817

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.249

Low

818412

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

383314

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.232

Low

427302

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

570036

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025