Protein: IWS1
Transcription factor SPN1 (Interacts with SPT6 protein 1) (Suppresses postrecruitment functions protein 1)

Gene: IWS1, SPN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 66
UniProt ID: Q06505

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016973 - poly(A)+ mRNA export from nucleus
GO:0034243 - regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

619173

SPT6
Transcription elongation factor SPT6

15

3

Small-scale

0.761

High

375510

RPB1
DNA-directed RNA polymerase II subunit RPB1

7

1

Small-scale

0.736

High

558271

RPB3
DNA-directed RNA polymerase II subunit RPB3

7

0

Small-scale

0.707

High

440104

RPB2
DNA-directed RNA polymerase II subunit RPB2

4

1

High-throughput

0.688

High

650397

SPT5
Transcription elongation factor SPT5

4

1

Small-scale

0.672

High

356742

H4
Histone H4

3

1

Small-scale

0.651

High

902085

H3
Histone H3

2

2

Small-scale

0.602

High

731935

ELF1
Transcription elongation factor 1

2

0

Small-scale

0.576

High

757158

RPB11
DNA-directed RNA polymerase II subunit RPB11

2

0

High-throughput

0.576

High

701347

SPT4
Transcription elongation factor SPT4

2

0

High-throughput

0.559

High

413013

KAPB
cAMP-dependent protein kinase type 2

1

2

High-throughput

0.536

High

593190

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.518

High

420173

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.479

High

603338

SNF2
Transcription regulatory protein SNF2

1

1

Small-scale

0.479

High

606766

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

663400

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

663919

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

810367

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

3

High-throughput

0.479

High

775267

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.460

High

407337

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

593091

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

593266

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

593346

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

628502

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

655581

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.458

High

688442

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

689968

ASF1
Histone chaperone ASF1

1

0

Small-scale

0.458

High

710034

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

775871

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

784881

T2FB
Transcription initiation factor IIF subunit beta

1

0

High-throughput

0.458

High

797279

IES1
Ino eighty subunit 1

1

0

Small-scale

0.458

High

960013

SEN1
Helicase SEN1

1

0

High-throughput

0.458

High

964143

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.458

High

965494

NOP3
Serine/arginine

1

0

Small-scale

0.458

High

987596

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.458

High

987599

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

987600

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

987601

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

987602

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

355656

H2B1
Histone H2B.1

1

4

High-throughput

0.445

High

512843

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

743697

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

472408

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

979850

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

987597

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

969426

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

2

High-throughput

0.407

High

692936

SPT16
FACT complex subunit SPT16

2

0

Small-scale

0.305

High

358271

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383364

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

413721

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

426165

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

471268

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

480329

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480898

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

482473

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

524455

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

632104

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

645667

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

706502

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

730130

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

745901

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

752683

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

820186

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

967775

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

987598

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

969205

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024