Protein: ENO
Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase)

Gene: ENO
Organism: Escherichia coli K-12
Interactions: 64
UniProt ID: P0A6P9

Gene Ontology (top 5):
GO:0000015 - phosphopyruvate hydratase complex
GO:0000287 - magnesium ion binding
GO:0004634 - phosphopyruvate hydratase activity
GO:0005576 - extracellular region
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

490568

ENO
Enolase

2

13

Small-scale

0.754

High

490598

RNE
Ribonuclease E

4

1

Small-scale

0.674

High

490575

PGK
Phosphoglycerate kinase

2

3

High-throughput

0.588

High

490580

SYT
Threonine--tRNA ligase

2

2

High-throughput

0.588

High

490581

SYK2
Lysine--tRNA ligase, heat inducible

2

4

High-throughput

0.588

High

490583

RNG
Ribonuclease G

2

1

High-throughput

0.588

High

490586

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.563

High

490594

RPE
Ribulose-phosphate 3-epimerase

2

0

High-throughput

0.563

High

490595

IBPA
Small heat shock protein IbpA

2

0

High-throughput

0.563

High

490576

RL9
Large ribosomal subunit protein bL9

1

1

High-throughput

0.536

High

490597

NADE
NH(3)-dependent NAD(+) synthetase

1

1

High-throughput

0.536

High

490574

NANE
Putative N-acetylmannosamine-6-phosphate 2-epimerase

1

0

High-throughput

0.513

High

490606

RDGC
Recombination-associated protein RdgC

1

0

High-throughput

0.513

High

490616

YFEX
Dye-decolorizing peroxidase YfeX

1

0

High-throughput

0.513

High

490621

YQJK
Uncharacterized protein YqjK

1

0

High-throughput

0.513

High

490578

SUCC
Succinate--CoA ligase [ADP-forming] subunit beta

1

1

High-throughput

0.500

High

416313

SYE
Glutamate--tRNA ligase

1

2

High-throughput

0.484

High

421089

PNP
Polyribonucleotide nucleotidyltransferase

1

1

High-throughput

0.484

High

490572

DNAK
Chaperone protein DnaK

1

5

High-throughput

0.484

High

490577

RS5
Small ribosomal subunit protein uS5

1

3

High-throughput

0.484

High

490579

RHLB
ATP-dependent RNA helicase RhlB

1

4

High-throughput

0.484

High

490608

CSPB
Cold shock-like protein CspB

1

2

High-throughput

0.484

High

490618

HXPB
Hexitol phosphatase B

1

1

High-throughput

0.484

High

490589

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.479

High

490599

MAK
Fructokinase

1

0

High-throughput

0.479

High

483687

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

1

High-throughput

0.479

High

489267

LEUC
3-isopropylmalate dehydratase large subunit

1

1

High-throughput

0.479

High

489450

GLPK
Glycerol kinase

1

1

Small-scale

0.479

High

490584

P5CR
Pyrroline-5-carboxylate reductase

1

2

High-throughput

0.479

High

490605

TKT2
Transketolase 2

1

3

High-throughput

0.479

High

490570

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

490571

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

393959

TONB
Protein TonB

1

0

High-throughput

0.458

High

490569

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.458

High

490573

NAGB
Glucosamine-6-phosphate deaminase

1

0

High-throughput

0.458

High

490588

DKSA
RNA polymerase-binding transcription factor DksA

1

0

High-throughput

0.458

High

490600

PABC
Aminodeoxychorismate lyase

1

0

High-throughput

0.458

High

490602

GLNE
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme

1

0

High-throughput

0.458

High

490603

POTF
Putrescine-binding periplasmic protein PotF

1

0

High-throughput

0.458

High

490611

AG43
Antigen 43

1

0

High-throughput

0.458

High

490614

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

490620

YQHD
NADPH-dependent aldehyde reductase YqhD

1

0

High-throughput

0.458

High

490607

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

1

High-throughput

0.457

High

490585

THIO
Thioredoxin 1

1

4

Small-scale

0.445

High

490587

PCNB
Poly(A) polymerase I

1

1

Small-scale

0.445

High

490601

LHR
Lhr helicase/uracil glycosylase

1

2

High-throughput

0.437

High

490591

PINR
Serine recombinase PinR

2

0

High-throughput

0.307

High

367338

AROF
Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive

1

0

High-throughput

0.279

Low

490592

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.279

Low

490615

RACR
DNA-binding transcriptional repressor RacR

1

0

High-throughput

0.279

Low

490617

YBDN
Uncharacterized protein YbdN

1

0

High-throughput

0.279

Low

490590

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.261

Low

490604

OTSA
Trehalose-6-phosphate synthase

1

0

High-throughput

0.261

Low

393845

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.249

Low

432110

APAH
Bis(5'-nucleosyl)-tetraphosphatase [symmetrical]

1

0

High-throughput

0.249

Low

490582

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.249

Low

490593

ACRA
Multidrug efflux pump subunit AcrA

1

0

High-throughput

0.249

Low

490596

TREA
Periplasmic trehalase

1

0

High-throughput

0.249

Low

490609

YHJD
Inner membrane protein YhjD

1

0

High-throughput

0.249

Low

490610

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

490612

YHDP
Intermembrane phospholipid transporter YhdP

1

0

High-throughput

0.249

Low

490613

TORZ
Trimethylamine-N-oxide reductase 2

1

0

High-throughput

0.249

Low

490619

YDJL
Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjL

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025