Protein: MBHT
Hydrogenase-2 small chain (HYD2) (EC 1.12.99.6) (Membrane-bound hydrogenase 2 small subunit) (NiFe hydrogenase)

Gene: MBHT, hybO
Organism: Escherichia coli K-12
Interactions: 18
UniProt ID: P69741

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0008901 - ferredoxin hydrogenase activity
GO:0009055 - electron transfer activity
GO:0009061 - anaerobic respiration
GO:0009375 - ferredoxin hydrogenase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

499021

MBHL
Hydrogenase-1 large chain

2

3

High-throughput

0.754

High

909897

HEMW
Heme chaperone HemW

1

2

High-throughput

0.541

High

500636

YJFN
Uncharacterized protein YjfN

1

0

High-throughput

0.518

High

999483

HCR
NADH oxidoreductase HCR

1

0

High-throughput

0.518

High

499611

KPYK1
Pyruvate kinase I

1

0

High-throughput

0.513

High

497604

THIO
Thioredoxin 1

1

1

High-throughput

0.494

High

494998

TIG
Trigger factor

1

0

Small-scale

0.426

High

497919

HYBE
Hydrogenase-2 operon protein HybE

6

0

Small-scale

0.378

High

496686

NAPD
Chaperone NapD

2

0

Small-scale

0.317

High

368971

SYGA
Glycine--tRNA ligase alpha subunit

1

0

High-throughput

0.282

High

498298

BOLA
DNA-binding transcriptional regulator BolA

1

0

High-throughput

0.282

High

500206

DPIA
Transcriptional regulatory protein DpiA

1

0

High-throughput

0.282

High

999484

CITC
[Citrate [pro-3S]-lyase] ligase

1

0

High-throughput

0.282

High

999485

ACDH
Acetaldehyde dehydrogenase

1

0

High-throughput

0.282

High

496134

PA1
Phospholipase A1

1

0

High-throughput

0.279

Low

616983

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.279

Low

999486

GPR
L-glyceraldehyde 3-phosphate reductase

1

0

High-throughput

0.279

Low

852331

YHBO
Protein/nucleic acid deglycase 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025