Protein: SYV
Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)

Gene: SYV, VAS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 79
UniProt ID: P07806

Gene Ontology (top 5):
GO:0002161 - aminoacyl-tRNA editing activity
GO:0004832 - valine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

430784

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

2

High-throughput

0.640

High

430755

HS104
Heat shock protein 104

3

6

High-throughput

0.633

High

430736

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

5

Small-scale

0.618

High

430787

TAF6
Transcription initiation factor TFIID subunit 6

2

0

High-throughput

0.595

High

365594

HSP82
ATP-dependent molecular chaperone HSP82

2

9

Small-scale

0.584

High

430744

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.571

High

430750

SIS1
Protein SIS1

2

4

High-throughput

0.571

High

430798

RNH1
Ribonuclease H

2

0

High-throughput

0.563

High

430740

HSP72
Heat shock protein SSA2

2

9

High-throughput

0.552

High

430779

SSB2
Ribosome-associated molecular chaperone SSB2

2

7

High-throughput

0.552

High

430800

PIN3
[PSI+] inducibility protein 3

1

1

High-throughput

0.541

High

430763

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.536

High

430783

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.536

High

430792

CDC14
Tyrosine-protein phosphatase CDC14

1

4

High-throughput

0.536

High

430773

KSP1
Serine/threonine-protein kinase KSP1

1

5

High-throughput

0.501

High

430781

PRK1
Actin-regulating kinase PRK1

1

1

Small-scale

0.501

High

430793

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

6

High-throughput

0.501

High

430749

FKBP
FK506-binding protein 1

1

1

High-throughput

0.500

High

430765

VPS21
Vacuolar protein sorting-associated protein 21

1

1

High-throughput

0.500

High

430805

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.500

High

420203

CALM
Calmodulin

1

1

High-throughput

0.489

High

430734

MYO1
Myosin-1

1

2

High-throughput

0.481

High

430746

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.481

High

430762

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.479

High

430771

IMB2
Importin subunit beta-2

1

0

High-throughput

0.479

High

388927

SYTC
Threonine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.479

High

389036

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

9

High-throughput

0.479

High

430738

IPB2
Protease B inhibitor 2

1

1

High-throughput

0.479

High

430743

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

430745

SYKC
Lysine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.479

High

430748

PYRC
Dihydroorotase

1

2

High-throughput

0.479

High

430753

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

430754

MLS1
Malate synthase 1

1

2

High-throughput

0.479

High

430759

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

430761

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

430766

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

430768

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

1

High-throughput

0.479

High

430774

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.479

High

430775

YHI0
Putative proline--tRNA ligase YHR020W

1

9

High-throughput

0.479

High

430776

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

430777

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

430788

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

430791

RAGAB
GTP-binding protein GTR1

1

1

Small-scale

0.479

High

430796

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

430801

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

430751

STE50
Protein STE50

1

0

High-throughput

0.460

High

430769

SEA4
SEH-associated protein 4

1

0

High-throughput

0.460

High

430785

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.460

High

430795

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.460

High

357162

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

430741

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

430756

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

430770

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.458

High

430772

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

430778

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

430780

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

430786

TIM54
Mitochondrial import inner membrane translocase subunit TIM54

1

0

High-throughput

0.458

High

430794

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.457

High

429582

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

4

High-throughput

0.457

High

430747

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.457

High

430760

SUI1
Eukaryotic translation initiation factor eIF-1

1

1

High-throughput

0.457

High

430735

HSP73
Heat shock protein SSA3

1

9

High-throughput

0.445

High

430739

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

430742

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.445

High

430758

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.445

High

430790

JJJ1
J protein JJJ1

1

3

High-throughput

0.445

High

430752

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

430767

PDX3
Pyridoxamine 5'-phosphate oxidase

1

1

High-throughput

0.437

High

430799

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

430802

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

430803

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.437

High

430804

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

430737

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

430764

NIC96
Nucleoporin NIC96

1

0

High-throughput

0.251

Low

430757

IES6
Chromatin-remodeling complex subunit IES6

1

0

High-throughput

0.249

Low

430782

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.249

Low

430789

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

Small-scale

0.249

Low

430806

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

430797

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024