Protein: NOP14
Nucleolar complex protein 14 (U three protein 2) (U3 small nucleolar RNA-associated protein 2) (U3 snoRNA-associated protein 2)

Gene: NOP14
Organism: Saccharomyces cerevisiae S288C
Interactions: 152
UniProt ID: Q99207

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

987714

NOC4
Nucleolar complex protein 4

12

2

Small-scale

0.759

High

748761

ENP1
Essential nuclear protein 1

10

1

Small-scale

0.754

High

979102

DHR1
Probable ATP-dependent RNA helicase DHR1

8

1

Small-scale

0.747

High

986778

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

5

1

Small-scale

0.727

High

811588

MPP10
U3 small nucleolar RNA-associated protein MPP10

5

1

Small-scale

0.723

High

634854

KRR1
KRR1 small subunit processome component

5

1

High-throughput

0.716

High

1015686

NOP58
Nucleolar protein 58

5

2

Small-scale

0.714

High

860784

UTP22
U3 small nucleolar RNA-associated protein 22

5

0

High-throughput

0.694

High

997073

BMS1
Ribosome biogenesis protein BMS1

4

2

High-throughput

0.694

High

635680

PWP2
Periodic tryptophan protein 2

4

3

High-throughput

0.691

High

358340

RS17A
Small ribosomal subunit protein eS17A

3

1

High-throughput

0.667

High

706580

RS3A1
Small ribosomal subunit protein eS1A

3

1

High-throughput

0.667

High

973705

UTP17
NET1-associated nuclear protein 1

3

4

High-throughput

0.667

High

988498

BFR2
Protein BFR2

3

1

High-throughput

0.667

High

716016

UTP20
U3 small nucleolar RNA-associated protein 20

4

0

High-throughput

0.664

High

861062

UTP8
U3 small nucleolar RNA-associated protein 8

4

0

Small-scale

0.664

High

982933

RRP5
rRNA biogenesis protein RRP5

4

0

Small-scale

0.661

High

985450

UTP13
U3 small nucleolar RNA-associated protein 13

3

3

High-throughput

0.656

High

987627

RRP9
Ribosomal RNA-processing protein 9

3

2

High-throughput

0.656

High

993383

RCL1
RNA 3'-terminal phosphate cyclase-like protein

3

1

High-throughput

0.656

High

979759

UTP14
U3 small nucleolar RNA-associated protein 14

3

1

High-throughput

0.650

High

756819

UTP9
U3 small nucleolar RNA-associated protein 9

3

0

High-throughput

0.638

High

866094

NAT10
RNA cytidine acetyltransferase

3

0

High-throughput

0.638

High

1015745

RRP12
Ribosomal RNA-processing protein 12

3

0

High-throughput

0.638

High

479559

RS24A
Small ribosomal subunit protein eS24A

2

1

High-throughput

0.628

High

549542

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

High-throughput

0.628

High

792653

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

High-throughput

0.613

High

767452

UTP7
U3 small nucleolar RNA-associated protein 7

2

1

High-throughput

0.611

High

1015095

SAS10
Something about silencing protein 10

2

0

High-throughput

0.610

High

645738

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.602

High

772709

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.588

High

864757

ESF2
Pre-rRNA-processing protein ESF2

2

0

High-throughput

0.588

High

970497

UTP6
U3 small nucleolar RNA-associated protein 6

2

0

High-throughput

0.588

High

1303344

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.588

High

866645

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

2

1

High-throughput

0.586

High

775414

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

995884

UTP16
U3 small nucleolar RNA-associated protein 16

2

0

High-throughput

0.585

High

481572

RS11B
Small ribosomal subunit protein uS17B

2

1

High-throughput

0.584

High

985844

UTP21
U3 small nucleolar RNA-associated protein 21

2

3

Small-scale

0.584

High

988665

UTP4
U3 small nucleolar RNA-associated protein 4

2

4

Small-scale

0.584

High

1015144

RRP6
Exosome complex exonuclease RRP6

2

1

High-throughput

0.584

High

499135

RL4A
Large ribosomal subunit protein uL4A

2

0

High-throughput

0.576

High

544675

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.571

High

976903

HAS1
ATP-dependent RNA helicase HAS1

2

1

High-throughput

0.571

High

479848

RS4A
Small ribosomal subunit protein eS4A

2

0

High-throughput

0.559

High

630300

RRP43
Exosome complex component RRP43

2

0

High-throughput

0.559

High

865444

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

495429

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

407431

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.547

High

730744

DHR2
Probable ATP-dependent RNA helicase DHR2

1

1

High-throughput

0.541

High

535299

RS17B
Small ribosomal subunit protein eS17B

1

1

High-throughput

0.536

High

991203

TSR1
Ribosome biogenesis protein TSR1

1

2

High-throughput

0.536

High

513380

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

865575

SQS1
Protein SQS1

1

0

High-throughput

0.518

High

632545

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.513

High

676510

XPO1
Exportin-1

1

0

High-throughput

0.513

High

791298

KRI1
Protein KRI1

1

0

High-throughput

0.513

High

615199

BUR1
Serine/threonine-protein kinase BUR1

1

0

High-throughput

0.493

High

691512

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.493

High

767050

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.493

High

793582

NSE4
Non-structural maintenance of chromosome element 4

1

0

High-throughput

0.493

High

861438

YG5B
Uncharacterized RNA-binding protein YGR250C

1

0

High-throughput

0.493

High

367157

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

413799

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

426234

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

593735

DBP4
ATP-dependent RNA helicase HCA4

1

1

High-throughput

0.479

High

628637

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

635448

BUD23
18S rRNA

1

1

Small-scale

0.479

High

707168

DCA13
Protein SOF1

1

2

High-throughput

0.479

High

733624

RL1D1
Ribosome biogenesis protein UTP30

1

2

High-throughput

0.479

High

743087

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

744266

MAK5
ATP-dependent RNA helicase MAK5

1

3

High-throughput

0.479

High

753202

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.479

High

754233

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.479

High

755019

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

758494

RRP8
25S rRNA

1

1

High-throughput

0.479

High

809610

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

810963

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.479

High

860832

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

866299

NOP15
Ribosome biogenesis protein 15

1

1

High-throughput

0.479

High

866598

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

902169

H3
Histone H3

1

3

High-throughput

0.479

High

978664

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.479

High

979272

UTP15
U3 small nucleolar RNA-associated protein 15

1

2

High-throughput

0.479

High

984332

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

985921

MRD1
Multiple RNA-binding domain-containing protein 1

1

1

Small-scale

0.479

High

993692

RRP44
Exosome complex exonuclease DIS3

1

1

High-throughput

0.479

High

996603

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.479

High

1015255

MAK21
Ribosome biogenesis protein MAK21

1

2

High-throughput

0.479

High

1015338

UTP12
U3 small nucleolar RNA-associated protein 12

1

3

High-throughput

0.479

High

1015413

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

1015631

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

987371

CORO
Coronin-like protein

1

2

High-throughput

0.470

High

514605

BIK1
Nuclear fusion protein BIK1

1

0

High-throughput

0.460

High

702735

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

746804

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

792470

GZF3
Protein GZF3

1

0

High-throughput

0.460

High

408511

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

480969

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

604648

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

630570

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

632177

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

650424

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

663804

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

665134

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

688513

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

700119

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

High-throughput

0.458

High

711098

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

732411

MUD2
Splicing factor MUD2

1

0

Small-scale

0.458

High

737248

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

752754

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

755223

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

768137

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

774302

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

774769

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

775310

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

775919

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

784546

DIM1
Dimethyladenosine transferase

1

0

Small-scale

0.458

High

799885

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

811818

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

816933

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

816993

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

820261

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

975891

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

983792

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

987117

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

994592

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

995865

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1014912

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1015266

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

1015665

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

1303345

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

492992

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

633735

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

865523

JJJ1
J protein JJJ1

1

1

High-throughput

0.445

High

471341

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

472478

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

1108067

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

705865

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

754850

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

699386

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.269

Low

629794

STE50
Protein STE50

1

0

High-throughput

0.251

Low

731374

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.251

Low

745968

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

762714

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

767279

VTC1
Vacuolar transporter chaperone complex subunit 1

1

0

High-throughput

0.249

Low

837534

MNN10
Probable alpha-1,6-mannosyltransferase MNN10

1

0

High-throughput

0.249

Low

860837

GYP2
GTPase-activating protein GYP2

1

0

High-throughput

0.249

Low

977491

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

837396

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low

971928

NU116
Nucleoporin NUP116/NSP116

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024