Protein: UFD2
E4 ubiquitin-protein ligase UFD2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase UFD2) (Ubiquitin conjugation factor E4) (Ubiquitin fusion degradation protein 2) (UB fusion protein 2)

Gene: UFD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: P54860

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636709

CDC48
Cell division control protein 48

13

9

Small-scale

0.764

High

697106

RAD23
UV excision repair protein RAD23

9

8

Small-scale

0.761

High

477406

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

6

7

Small-scale

0.735

High

819479

DSK2
Ubiquitin domain-containing protein DSK2

6

10

Small-scale

0.733

High

710572

UBX1
UBX domain-containing protein 1

5

3

Small-scale

0.722

High

366723

HSP82
ATP-dependent molecular chaperone HSP82

4

4

High-throughput

0.676

High

707244

NPL4
Nuclear protein localization protein 4

4

0

Small-scale

0.669

High

549827

UBC4
Ubiquitin-conjugating enzyme E2 4

1

20

Small-scale

0.647

High

873347

UFD2
E4 ubiquitin-protein ligase UFD2

1

13

Small-scale

0.647

High

544233

HSC82
ATP-dependent molecular chaperone HSC82

3

4

High-throughput

0.633

High

797102

OTU1
Ubiquitin thioesterase OTU1

2

1

Small-scale

0.632

High

873350

VMS1
tRNA endonuclease VMS1

3

0

Small-scale

0.628

High

858699

UFD1
Ubiquitin fusion degradation protein 1

2

0

Small-scale

0.585

High

769165

SSB2
Ribosome-associated molecular chaperone SSB2

2

12

High-throughput

0.552

High

873353

ENV7
Serine/threonine-protein kinase ENV7

1

4

High-throughput

0.536

High

873352

ARR1
Arsenical-resistance protein ARR1

1

0

Small-scale

0.529

High

750071

TSL1
Trehalose synthase complex regulatory subunit TSL1

1

0

High-throughput

0.513

High

767203

HMF1
Protein HMF1

1

0

High-throughput

0.513

High

748976

UBX7
UBX domain-containing protein 7

1

3

High-throughput

0.508

High

703165

UFD4
Ubiquitin fusion degradation protein 4

1

2

Small-scale

0.501

High

539902

RAD4
DNA repair protein RAD4

1

1

Small-scale

0.479

High

680921

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

687980

IMB3
Importin subunit beta-3

1

1

High-throughput

0.479

High

767704

IMB4
Importin subunit beta-4

1

1

High-throughput

0.479

High

860050

CDH1
APC/C activator protein CDH1

1

3

Small-scale

0.479

High

778488

MAD2
Mitotic spindle checkpoint component MAD2

1

0

High-throughput

0.460

High

407241

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

485799

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.458

High

663021

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

774488

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.458

High

873349

UBX2
UBX domain-containing protein 2

1

0

Small-scale

0.458

High

478426

HSP77
Import motor subunit, mitochondrial

1

16

High-throughput

0.445

High

492109

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

494693

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.445

High

512336

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

628352

SIS1
Protein SIS1

1

6

High-throughput

0.445

High

633472

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

695290

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

705519

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

766158

HSP7E
Heat shock protein SSC3, mitochondrial

1

15

High-throughput

0.445

High

772578

JEM1
DnaJ-like chaperone JEM1

1

11

High-throughput

0.445

High

503125

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.437

High

731069

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.437

High

745814

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

854653

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

873351

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

471195

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

690793

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.249

Low

747980

FZO1
Mitofusin FZO1

1

0

Small-scale

0.249

Low

873348

PEX29
Peroxisomal membrane protein PEX29

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024