Protein: PROA
Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (GSA dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)

Gene: PROA, PRO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: P54885

Gene Ontology (top 5):
GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006561 - proline biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

635969

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

6

1

High-throughput

0.732

High

873386

PROA
Gamma-glutamyl phosphate reductase

1

14

High-throughput

0.698

High

639280

MSH2
DNA mismatch repair protein MSH2

2

0

High-throughput

0.595

High

544235

HSC82
ATP-dependent molecular chaperone HSC82

2

7

High-throughput

0.584

High

797522

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

6

High-throughput

0.584

High

366725

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.571

High

494696

HSP72
Heat shock protein SSA2

2

17

High-throughput

0.552

High

512338

SSB1
Ribosome-associated molecular chaperone SSB1

2

16

High-throughput

0.552

High

443987

CISY2
Citrate synthase, peroxisomal

1

3

High-throughput

0.515

High

784408

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.494

High

611019

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.480

High

873389

AUS1
ATP-dependent permease AUS1

1

0

High-throughput

0.480

High

628353

SIS1
Protein SIS1

1

7

High-throughput

0.479

High

663023

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

677538

MLS1
Malate synthase 1

1

2

High-throughput

0.479

High

688369

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

691099

HOG1
Mitogen-activated protein kinase HOG1

1

5

High-throughput

0.479

High

773897

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

6

High-throughput

0.479

High

873391

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.479

High

653816

PEP3
Vacuolar membrane protein PEP3

1

1

High-throughput

0.470

High

745508

KMO
Kynurenine 3-monooxygenase

1

0

High-throughput

0.458

High

759501

MPT5
Suppressor protein MPT5

1

0

High-throughput

0.458

High

873387

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

873390

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

771580

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

4

High-throughput

0.457

High

368312

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

492111

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.445

High

541772

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.445

High

633474

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

695292

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

769167

SSB2
Ribosome-associated molecular chaperone SSB2

1

16

High-throughput

0.445

High

873392

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

625897

TSR4
20S rRNA accumulation protein 4

1

0

High-throughput

0.438

High

745815

NU170
Nucleoporin NUP170

1

4

High-throughput

0.437

High

873388

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

784947

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

0

High-throughput

0.282

High

856951

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.251

Low

450331

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

743787

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

744338

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

822898

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

859473

YGL7
Uncharacterized protein YGL117W

1

0

High-throughput

0.249

Low

861170

TPO2
Polyamine transporter 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024