Protein: PUR91
Bifunctional purine biosynthesis protein ADE16 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)]

Gene: PUR91, ADE16
Organism: Saccharomyces cerevisiae S288C
Interactions: 34
UniProt ID: P54113

Gene Ontology (top 5):
GO:0003937 - IMP cyclohydrolase activity
GO:0004643 - phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0005829 - cytosol
GO:0006164 - purine nucleotide biosynthetic process
GO:0006189 - 'de novo' IMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

742733

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

5

3

High-throughput

0.918

High

867502

PUR91
Bifunctional purine biosynthesis protein ADE16 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

2

3

High-throughput

0.785

High

696380

PP12
Serine/threonine-protein phosphatase PP1-2

5

1

High-throughput

0.652

High

740834

SOL2
6-phosphogluconolactonase-like protein 2

2

3

High-throughput

0.611

High

512319

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.601

High

838499

SOL1
6-phosphogluconolactonase-like protein 1

2

3

High-throughput

0.588

High

797515

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

769150

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.552

High

867503

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

0

High-throughput

0.518

High

696817

VATD
V-type proton ATPase subunit D

1

1

High-throughput

0.494

High

867507

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

2

High-throughput

0.494

High

628343

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

756997

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

523430

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.458

High

752179

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.458

High

867505

MUK1
Protein MUK1

1

0

High-throughput

0.458

High

550096

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.445

High

680916

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

618243

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.438

High

755917

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.438

High

663010

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

860559

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.437

High

867506

TAF7
Transcription initiation factor TFIID subunit 7

1

1

High-throughput

0.437

High

368302

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

867504

REG1
Resistance to glucose repression protein 1

2

0

High-throughput

0.320

High

425372

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

664988

BMH1
Protein BMH1

1

0

High-throughput

0.279

Low

676279

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

748481

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.269

Low

859728

MPS2
Monopolar spindle protein 2

1

0

Small-scale

0.251

Low

752051

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

819056

BPL1
Biotin--protein ligase

1

0

High-throughput

0.249

Low

785155

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024