Protein: PBPB
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.99.28) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]

Gene: PBPB, mrcB
Organism: Escherichia coli K-12
Interactions: 18
UniProt ID: P02919

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0008360 - regulation of cell shape
GO:0008658 - penicillin binding
GO:0008955 - peptidoglycan glycosyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393925

FTSI
Peptidoglycan D,D-transpeptidase FtsI

3

16

Small-scale

0.812

High

393914

PBPB
Penicillin-binding protein 1B

2

15

Small-scale

0.737

High

393927

FTSN
Cell division protein FtsN

2

3

Small-scale

0.639

High

393920

LPOB
Penicillin-binding protein activator LpoB

2

0

Small-scale

0.576

High

393838

PBPA
Penicillin-binding protein 1A

1

16

Small-scale

0.575

High

393915

POXB
Pyruvate dehydrogenase [ubiquinone]

1

0

High-throughput

0.513

High

393917

TALB
Transaldolase B

1

1

High-throughput

0.500

High

393924

DBHA
DNA-binding protein HU-alpha

1

2

High-throughput

0.500

High

393919

MLTA
Membrane-bound lytic murein transglycosylase A

1

0

Small-scale

0.458

High

393921

FTSW
Probable peptidoglycan glycosyltransferase FtsW

1

4

Small-scale

0.457

High

393918

MIPA
MltA-interacting protein

1

0

Small-scale

0.426

High

393929

AMIC
N-acetylmuramoyl-L-alanine amidase AmiC

1

0

Small-scale

0.426

High

393928

RHAB
L-Rhamnulokinase

1

0

High-throughput

0.279

Low

393923

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.261

Low

393926

PPSA
Phosphoenolpyruvate synthase

1

0

High-throughput

0.261

Low

393916

UVRA
UvrABC system protein A

1

0

Small-scale

0.249

Low

393922

DKSA
RNA polymerase-binding transcription factor DksA

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025