Protein: SERA
D-3-phosphoglycerate dehydrogenase 1 (3-PGDH 1) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399)

Gene: SERA, SER3
Organism: Saccharomyces cerevisiae S288C
Interactions: 49
UniProt ID: P40054

Gene Ontology (top 5):
GO:0004617 - phosphoglycerate dehydrogenase activity
GO:0005737 - cytoplasm
GO:0006564 - L-serine biosynthetic process
GO:0009070 - serine family amino acid biosynthetic process
GO:0051287 - NAD binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

767349

SER33
D-3-phosphoglycerate dehydrogenase 2

9

16

Small-scale

0.969

High

767348

SERA
D-3-phosphoglycerate dehydrogenase 1

3

15

High-throughput

0.829

High

715197

TOR1
Serine/threonine-protein kinase TOR1

2

1

Small-scale

0.594

High

543818

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.584

High

697642

FADH
S-(hydroxymethyl)glutathione dehydrogenase

1

1

High-throughput

0.541

High

704209

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

4

High-throughput

0.541

High

743148

BOB1
Protein BOB1

1

7

High-throughput

0.541

High

763558

BDH1
(R,R)-butanediol dehydrogenase

1

1

High-throughput

0.541

High

767363

YN12B
Transposon Ty1-NL2 Gag-Pol polyprotein

1

2

High-throughput

0.541

High

676086

XPO1
Exportin-1

1

2

High-throughput

0.536

High

767351

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.533

High

767350

MAF1
Repressor of RNA polymerase III transcription MAF1

1

0

High-throughput

0.518

High

767359

CYK3
Cytokinesis protein 3

1

0

High-throughput

0.518

High

548406

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

4

High-throughput

0.494

High

767353

NUP42
Nucleoporin NUP42

1

1

High-throughput

0.494

High

756502

KOG1
Target of rapamycin complex 1 subunit KOG1

1

7

High-throughput

0.481

High

703635

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

705228

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

713229

TSA1
Peroxiredoxin TSA1

1

4

Small-scale

0.479

High

753823

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

767352

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

767360

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

2

High-throughput

0.479

High

744987

PPS1
Dual specificity protein phosphatase PPS1

1

2

High-throughput

0.464

High

767355

NU116
Nucleoporin NUP116/NSP116

1

1

High-throughput

0.464

High

491357

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

494078

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

511474

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

694787

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

375406

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.437

High

405650

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

413532

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.437

High

425978

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

480695

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

628107

SIS1
Protein SIS1

1

3

High-throughput

0.437

High

662343

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

700441

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

767354

YPT32
GTP-binding protein YPT32/YPT11

1

1

High-throughput

0.437

High

767356

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.437

High

746659

CST26
2-acyl-1-lysophosphatidylinositol acyltransferase

1

0

High-throughput

0.282

High

767361

TMS1
Membrane protein TMS1

1

0

High-throughput

0.282

High

767362

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.282

High

752279

PPAC
Acid phosphatase PHO12

1

0

High-throughput

0.269

Low

558080

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.249

Low

711137

SEG2
Eisosome protein SEG2

1

0

High-throughput

0.249

Low

756933

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

767357

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

767358

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

755230

IPI1
Pre-rRNA-processing protein IPI1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024