Protein: SYK2
Lysine--tRNA ligase, heat inducible (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)

Gene: SYK2, lysU
Organism: Escherichia coli K-12
Interactions: 58
UniProt ID: P0A8N5

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0000287 - magnesium ion binding
GO:0004824 - lysine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

495646

DPO3B
Beta sliding clamp

2

0

High-throughput

0.720

High

495618

SYK1
Lysine--tRNA ligase

1

12

High-throughput

0.625

High

495642

SYK2
Lysine--tRNA ligase, heat inducible

1

12

High-throughput

0.618

High

480574

PFLB
Formate acetyltransferase 1

2

1

High-throughput

0.588

High

490581

ENO
Enolase

2

4

High-throughput

0.588

High

491999

PGK
Phosphoglycerate kinase

2

1

High-throughput

0.588

High

495495

SYS
Serine--tRNA ligase

2

13

High-throughput

0.588

High

495647

G3P1
Glyceraldehyde-3-phosphate dehydrogenase A

2

1

High-throughput

0.588

High

495655

SSPA
Stringent starvation protein A

2

1

High-throughput

0.588

High

495671

CLPB
Chaperone protein ClpB

2

3

High-throughput

0.588

High

495676

DCEB
Glutamate decarboxylase beta

2

1

High-throughput

0.588

High

495677

YDHJ
Uncharacterized protein YdhJ

2

1

High-throughput

0.588

High

495669

RL2
Large ribosomal subunit protein uL2

2

0

High-throughput

0.585

High

495013

TNAA
Tryptophanase

2

0

High-throughput

0.563

High

495037

TPIS
Triosephosphate isomerase

2

0

High-throughput

0.563

High

495380

NQOR
NAD(P)H dehydrogenase

2

0

High-throughput

0.563

High

495648

ADHE
Bifunctional aldehyde-alcohol dehydrogenase AdhE

2

0

High-throughput

0.563

High

495652

CYSK
Cysteine synthase A

2

0

High-throughput

0.563

High

495653

DPS
DNA protection during starvation protein

2

0

High-throughput

0.563

High

495656

YFCZ
UPF0381 protein YfcZ

2

0

High-throughput

0.563

High

495658

NLPI
Lipoprotein NlpI

2

0

High-throughput

0.563

High

495664

FDHD
Sulfur carrier protein FdhD

2

0

High-throughput

0.563

High

495674

RL25
Large ribosomal subunit protein bL25

2

0

High-throughput

0.563

High

495667

YHJX
Uncharacterized MFS-type transporter YhjX

2

1

High-throughput

0.537

High

368800

SYI
Isoleucine--tRNA ligase

1

10

High-throughput

0.536

High

382657

RS7
Small ribosomal subunit protein uS7

1

2

High-throughput

0.484

High

489508

CH60
Chaperonin GroEL

1

1

High-throughput

0.484

High

490500

EFG
Elongation factor G

1

4

High-throughput

0.484

High

493209

RS10
Small ribosomal subunit protein uS10

1

2

High-throughput

0.484

High

493304

RS11
Small ribosomal subunit protein uS11

1

1

High-throughput

0.484

High

493693

RS2
Small ribosomal subunit protein uS2

1

5

High-throughput

0.484

High

493858

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.484

High

495644

RPOB
DNA-directed RNA polymerase subunit beta

1

2

High-throughput

0.484

High

495649

MREB
Cell shape-determining protein MreB

1

6

High-throughput

0.484

High

495659

ODP1
Pyruvate dehydrogenase E1 component

1

1

High-throughput

0.484

High

495660

EFTU1
Elongation factor Tu 1

1

10

High-throughput

0.484

High

495666

RLMN
Dual-specificity RNA methyltransferase RlmN

1

1

High-throughput

0.484

High

495673

GRCA
Autonomous glycyl radical cofactor

1

1

High-throughput

0.484

High

495675

DCEA
Glutamate decarboxylase alpha

1

1

High-throughput

0.484

High

495672

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

1

1

High-throughput

0.479

High

367309

DCDA
Diaminopimelate decarboxylase

1

0

High-throughput

0.464

High

493135

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

495643

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.464

High

495650

CSPC
Cold shock-like protein CspC

1

0

High-throughput

0.464

High

495651

ACCA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

1

0

High-throughput

0.464

High

495662

CATE
Catalase HPII

1

0

High-throughput

0.464

High

495670

RL24
Large ribosomal subunit protein uL24

1

0

High-throughput

0.464

High

495645

RIMI
[Ribosomal protein bS18]-alanine N-acetyltransferase

1

0

High-throughput

0.458

High

495654

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.458

High

495661

EFTU2
Elongation factor Tu 2

1

10

High-throughput

0.445

High

495678

YAGJ
Protein YagJ

2

0

High-throughput

0.307

High

495679

FOCB
Formate channel FocB

2

0

High-throughput

0.307

High

495665

YEHI
Uncharacterized protein YehI

1

0

High-throughput

0.279

Low

495657

YGIW
Protein YgiW

1

0

High-throughput

0.253

Low

495663

WCAI
Putative colanic acid biosynthesis glycosyl transferase WcaI

1

0

High-throughput

0.253

Low

393866

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.249

Low

495668

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025