HitPredict - High confidence protein-protein interactions

Protein: ES8L3
Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3)

Gene: ES8L3, EPS8L3
Organism: Homo sapiens
Interactions: 7
UniProt ID: Q8TE67

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007266 - Rho protein signal transduction

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1316681	ABI1 Abl interactor 1	1	20	Small-scale	0.553	High
1006577	SRPK2 SRSF protein kinase 2	1	9	High-throughput	0.550	High
869505	TNFL6 Tumor necrosis factor ligand superfamily member 6	1	11	Small-scale	0.501	High
460271	CD3E T-cell surface glycoprotein CD3 epsilon chain	1	5	Small-scale	0.479	High
1352118	HDAC6 Protein deacetylase HDAC6	1	4	High-throughput	0.479	High
1352119	ZRAN1 Ubiquitin thioesterase ZRANB1	1	5	High-throughput	0.479	High
1352120	TRI17 E3 ubiquitin-protein ligase TRIM17	1	7	Small-scale	0.479	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025