Protein: ABI1
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)

Gene: ABI1
Organism: Homo sapiens
Interactions: 227
UniProt ID: Q8IZP0

Gene Ontology (top 5):
GO:0001756 - somitogenesis
GO:0001764 - neuron migration
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1316726

NCKP1
Nck-associated protein 1

8

8

Small-scale

0.974

High

362318

ABL1
Tyrosine-protein kinase ABL1

7

20

Small-scale

0.974

High

1316725

BAIP2
BAR/IMD domain-containing adapter protein 2

6

20

Small-scale

0.950

High

1272177

CYFP1
Cytoplasmic FMR1-interacting protein 1

6

10

Small-scale

0.935

High

1316713

ABI2
Abl interactor 2

5

17

High-throughput

0.931

High

222140

NCK2
Cytoplasmic protein NCK2

5

19

Small-scale

0.919

High

594045

NCK1
SH2/SH3 adapter protein NCK1

4

20

Small-scale

0.893

High

1090353

EPS8
Epidermal growth factor receptor kinase substrate 8

3

20

Small-scale

0.857

High

1316682

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

3

20

Small-scale

0.839

High

1316694

CYFP2
Cytoplasmic FMR1-interacting protein 2

3

10

Small-scale

0.817

High

320250

SRBS2
Sorbin and SH3 domain-containing protein 2

2

20

High-throughput

0.783

High

1150876

CIP4
Cdc42-interacting protein 4

2

20

High-throughput

0.783

High

440142

LCK
Tyrosine-protein kinase Lck

2

20

Small-scale

0.768

High

463642

LYN
Tyrosine-protein kinase Lyn

2

20

Small-scale

0.768

High

363550

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.754

High

1060683

SOS1
Son of sevenless homolog 1

1

14

Small-scale

0.747

High

1316732

WASF2
Actin-binding protein WASF2

6

20

Small-scale

0.732

High

896578

VASP
Vasodilator-stimulated phosphoprotein

6

20

High-throughput

0.728

High

699802

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

15

Small-scale

0.724

High

1316711

HOME3
Homer protein homolog 3

5

20

High-throughput

0.721

High

1316686

WASF1
Actin-binding protein WASF1

5

20

High-throughput

0.712

High

1316702

SRBS1
Sorbin and SH3 domain-containing protein 1

1

20

High-throughput

0.698

High

1316703

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.698

High

1258032

RAPH1
Ras-associated and pleckstrin homology domains-containing protein 1

1

10

High-throughput

0.691

High

572841

NCF1
Neutrophil cytosol factor 1

1

20

Small-scale

0.683

High

1316675

ENAH
Protein enabled homolog

3

20

Small-scale

0.679

High

965774

HNRPK
Heterogeneous nuclear ribonucleoprotein K

3

6

High-throughput

0.667

High

1211745

UBX11
UBX domain-containing protein 11

3

1

High-throughput

0.667

High

1316676

ZN511
Zinc finger protein 511

3

1

High-throughput

0.667

High

1316691

LHX4
LIM/homeobox protein Lhx4

3

11

High-throughput

0.667

High

1316693

DTBP1
Dysbindin

3

2

High-throughput

0.667

High

1316683

BRK1
Protein BRICK1

3

4

High-throughput

0.662

High

386474

SPTA1
Spectrin alpha chain, erythrocytic 1

1

13

Small-scale

0.653

High

136411

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

Small-scale

0.647

High

155169

SOCS7
Suppressor of cytokine signaling 7

1

15

Small-scale

0.647

High

187380

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

18

Small-scale

0.647

High

440627

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.647

High

456112

FES
Tyrosine-protein kinase Fes/Fps

1

20

Small-scale

0.647

High

463156

YES
Tyrosine-protein kinase Yes

1

20

Small-scale

0.647

High

473442

HCK
Tyrosine-protein kinase HCK

1

20

Small-scale

0.647

High

486703

FGR
Tyrosine-protein kinase Fgr

1

20

Small-scale

0.647

High

557380

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.647

High

584565

VAV
Proto-oncogene vav

1

20

Small-scale

0.647

High

597899

FER
Tyrosine-protein kinase Fer

1

20

Small-scale

0.647

High

619076

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

2

Small-scale

0.647

High

635730

RASA1
Ras GTPase-activating protein 1

1

20

Small-scale

0.647

High

728329

AKT1
RAC-alpha serine/threonine-protein kinase

1

11

Small-scale

0.647

High

840970

ABL2
Tyrosine-protein kinase ABL2

1

20

Small-scale

0.647

High

841021

FRK
Tyrosine-protein kinase FRK

1

20

Small-scale

0.647

High

855681

CRK
Adapter molecule crk

1

20

Small-scale

0.647

High

855902

CRKL
Crk-like protein

1

20

Small-scale

0.647

High

913663

VAV2
Guanine nucleotide exchange factor VAV2

1

20

Small-scale

0.647

High

987766

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.647

High

1065087

ITK
Tyrosine-protein kinase ITK/TSK

1

20

Small-scale

0.647

High

1102344

GRB10
Growth factor receptor-bound protein 10

1

20

Small-scale

0.647

High

1316688

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

20

Small-scale

0.647

High

537494

HSP7C
Heat shock cognate 71 kDa protein

3

7

Small-scale

0.633

High

1316716

NHSL3
NHS-like protein 3

4

16

High-throughput

0.630

High

257141

CCD22
Coiled-coil domain-containing protein 22

2

9

High-throughput

0.628

High

966596

1433G
14-3-3 protein gamma

2

20

High-throughput

0.628

High

1316724

WASF3
Actin-binding protein WASF3

2

20

High-throughput

0.628

High

1311199

RHG12
Rho GTPase-activating protein 12

1

16

High-throughput

0.618

High

541585

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

710356

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

710862

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.618

High

761258

RYK
Tyrosine-protein kinase RYK

1

20

Small-scale

0.618

High

1156993

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.618

High

1316672

ABI1
Abl interactor 1

1

16

High-throughput

0.618

High

1316709

ES8L2
Epidermal growth factor receptor kinase substrate 8-like protein 2

1

20

Small-scale

0.618

High

1316723

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.618

High

643516

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

2

2

High-throughput

0.611

High

188004

EIF3H
Eukaryotic translation initiation factor 3 subunit H

2

13

High-throughput

0.606

High

262403

DTNB
Dystrobrevin beta

2

6

High-throughput

0.606

High

682067

RBTN1
Rhombotin-1

2

17

High-throughput

0.606

High

930750

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

8

High-throughput

0.606

High

1040496

HHEX
Hematopoietically-expressed homeobox protein HHEX

2

4

High-throughput

0.606

High

1123038

FHL2
Four and a half LIM domains protein 2

2

12

High-throughput

0.606

High

1210591

SYVM
Valine--tRNA ligase, mitochondrial

2

3

High-throughput

0.606

High

1243754

FXL19
F-box/LRR-repeat protein 19

2

3

High-throughput

0.606

High

1295191

HOME1
Homer protein homolog 1

2

20

High-throughput

0.606

High

1316679

CCHCR
Coiled-coil alpha-helical rod protein 1

2

9

High-throughput

0.606

High

1316695

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

3

High-throughput

0.606

High

1316701

RBM15
RNA-binding protein 15

2

2

High-throughput

0.606

High

1316717

RCOR3
REST corepressor 3

2

3

High-throughput

0.606

High

1316729

MB212
Protein mab-21-like 2

2

2

High-throughput

0.606

High

1211399

NHSL1
NHS-like protein 1

3

16

High-throughput

0.593

High

582874

EZRI
Ezrin

2

14

High-throughput

0.584

High

1316700

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

12

High-throughput

0.575

High

1192197

AMZ1
Archaemetzincin-1

2

1

High-throughput

0.574

High

123766

MYO1C
Unconventional myosin-Ic

2

8

High-throughput

0.571

High

396482

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

415706

HSPB1
Heat shock protein beta-1

2

3

High-throughput

0.571

High

424960

ADT2
ADP/ATP translocase 2

2

3

High-throughput

0.571

High

457546

TBB5
Tubulin beta chain

2

1

High-throughput

0.571

High

549637

PRPS2
Ribose-phosphate pyrophosphokinase 2

2

3

High-throughput

0.571

High

600858

HSP76
Heat shock 70 kDa protein 6

2

7

High-throughput

0.571

High

683606

ITA3
Integrin alpha-3

2

5

High-throughput

0.571

High

954534

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

3

High-throughput

0.571

High

988153

TRA2B
Transformer-2 protein homolog beta

2

3

High-throughput

0.571

High

997420

TBB4B
Tubulin beta-4B chain

2

1

High-throughput

0.571

High

1024405

S25A3
Solute carrier family 25 member 3

2

5

High-throughput

0.571

High

1039964

AKA12
A-kinase anchor protein 12

2

4

High-throughput

0.571

High

1040164

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

2

2

High-throughput

0.571

High

1316714

BCLF1
Bcl-2-associated transcription factor 1

2

2

High-throughput

0.571

High

1316721

COR1C
Coronin-1C

2

8

High-throughput

0.571

High

1316733

NS1BP
Influenza virus NS1A-binding protein

2

4

High-throughput

0.571

High

1288722

KTN1
Kinectin

1

6

High-throughput

0.568

High

1143413

PCM1
Pericentriolar material 1 protein

1

2

High-throughput

0.560

High

319126

NFASC
Neurofascin

2

1

High-throughput

0.553

High

1179979

CCD57
Coiled-coil domain-containing protein 57

2

8

High-throughput

0.553

High

1213002

SKT
Sickle tail protein homolog

2

6

High-throughput

0.553

High

1316704

ENKD1
Enkurin domain-containing protein 1

2

2

High-throughput

0.553

High

1316708

F124B
Protein FAM124B

2

1

High-throughput

0.553

High

1316681

ES8L3
Epidermal growth factor receptor kinase substrate 8-like protein 3

1

20

Small-scale

0.553

High

1316706

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

139724

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.549

High

697586

PYR1
Multifunctional protein CAD

2

0

High-throughput

0.547

High

717223

KCY
UMP-CMP kinase

2

0

High-throughput

0.547

High

1198188

PDCD4
Programmed cell death protein 4

2

0

High-throughput

0.547

High

1199208

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

2

0

High-throughput

0.547

High

1316720

DPP2
Dipeptidyl peptidase 2

2

0

High-throughput

0.547

High

900027

FXR1
RNA-binding protein FXR1

1

3

High-throughput

0.541

High

1040332

DYST
Dystonin

1

14

High-throughput

0.541

High

1316684

SYNE2
Nesprin-2

1

11

High-throughput

0.541

High

1316689

TSC1
Hamartin

1

19

High-throughput

0.541

High

1316728

TLN1
Talin-1

1

20

High-throughput

0.541

High

1205197

NHSL2
NHS-like protein 2

2

20

High-throughput

0.537

High

459672

PROF1
Profilin-1

1

6

High-throughput

0.536

High

530061

TAU
Microtubule-associated protein tau

1

17

High-throughput

0.536

High

587137

ITF2
Transcription factor 4

1

2

High-throughput

0.536

High

691232

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

854158

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

952953

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.536

High

971765

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.536

High

990480

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

993243

ACTG
Actin, cytoplasmic 2

1

20

High-throughput

0.536

High

1049543

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1124646

SRC8
Src substrate cortactin

1

20

High-throughput

0.536

High

1192058

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

2

High-throughput

0.536

High

1258640

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

1

High-throughput

0.536

High

1292040

THOC6
THO complex subunit 6

1

18

High-throughput

0.536

High

1316678

RIN3
Ras and Rab interactor 3

1

20

High-throughput

0.536

High

1316698

SPTCS
Spatacsin

1

1

High-throughput

0.536

High

1316699

RBM14
RNA-binding protein 14

1

1

High-throughput

0.536

High

1316705

CAD23
Cadherin-23

1

3

High-throughput

0.536

High

1316712

FGOP2
FGFR1 oncogene partner 2

1

2

High-throughput

0.536

High

1316731

KC1G3
Casein kinase I isoform gamma-3

1

13

High-throughput

0.536

High

651378

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.534

High

565420

ITA4
Integrin alpha-4

1

5

Small-scale

0.527

High

240103

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

3

High-throughput

0.521

High

996764

TBA1B
Tubulin alpha-1B chain

2

3

High-throughput

0.521

High

1127968

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

2

3

High-throughput

0.521

High

1316719

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.518

High

1095410

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

8

Small-scale

0.515

High

479219

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

0

High-throughput

0.513

High

717892

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.513

High

1238068

CGB2
Choriogonadotropin subunit beta variant 2

2

1

High-throughput

0.504

High

163802

TCRG1
Transcription elongation regulator 1

1

11

High-throughput

0.501

High

185844

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

1097947

CBLB
E3 ubiquitin-protein ligase CBL-B

1

20

Small-scale

0.501

High

1316722

CBLC
E3 ubiquitin-protein ligase CBL-C

1

20

Small-scale

0.501

High

1256448

K0408
Uncharacterized protein KIAA0408

1

2

High-throughput

0.494

High

1316697

MR1L1
MORF4 family-associated protein 1-like 1

1

5

High-throughput

0.494

High

1316730

MOFA1
MORF4 family-associated protein 1

1

5

High-throughput

0.494

High

733393

CCR1
C-C chemokine receptor type 1

1

8

High-throughput

0.489

High

1316710

PAAT
ATPase PAAT

1

2

High-throughput

0.489

High

258388

GAS7
Growth arrest-specific protein 7

1

16

High-throughput

0.481

High

1314651

SRRM1
Serine/arginine repetitive matrix protein 1

1

12

High-throughput

0.481

High

127134

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.480

High

132156

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

High-throughput

0.479

High

189695

STX7
Syntaxin-7

1

8

High-throughput

0.479

High

327352

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

374748

RASH
GTPase HRas

1

14

High-throughput

0.479

High

375706

RASK
GTPase KRas

1

17

High-throughput

0.479

High

540555

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

556202

CADH1
Cadherin-1

1

8

High-throughput

0.479

High

581160

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

589129

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

635540

NEBU
Nebulin

1

19

Small-scale

0.479

High

695913

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

773763

ACTN2
Alpha-actinin-2

1

5

High-throughput

0.479

High

831046

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

901929

RAB9A
Ras-related protein Rab-9A

1

5

High-throughput

0.479

High

953556

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

978152

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

988517

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

995691

ACTC
Actin, alpha cardiac muscle 1

1

20

High-throughput

0.479

High

1087184

STX4
Syntaxin-4

1

9

High-throughput

0.479

High

1096752

RFA4
Replication protein A 30 kDa subunit

1

10

High-throughput

0.479

High

1121272

TRI14
Tripartite motif-containing protein 14

1

7

High-throughput

0.479

High

1145003

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.479

High

1146434

KS6A2
Ribosomal protein S6 kinase alpha-2

1

13

High-throughput

0.479

High

1227037

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.479

High

1233339

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1238436

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

1247745

NHS
Actin remodeling regulator NHS

1

15

High-throughput

0.479

High

1254585

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

1316677

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1316687

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1316690

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

1316692

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.479

High

1316718

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1096589

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

1187325

CMA1D
Protein CIMAP1D

1

0

High-throughput

0.458

High

1231730

NXN
Nucleoredoxin

1

0

High-throughput

0.458

High

1291059

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

Small-scale

0.458

High

1316715

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

280716

PR40A
Pre-mRNA-processing factor 40 homolog A

1

20

High-throughput

0.457

High

877494

HSP77
Putative heat shock 70 kDa protein 7

1

8

High-throughput

0.445

High

934847

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

1025386

CDK6
Cyclin-dependent kinase 6

1

4

Small-scale

0.445

High

1110497

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

8

High-throughput

0.445

High

768622

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

1159746

OCLN
Occludin

1

3

High-throughput

0.437

High

1316673

NIN
Ninein

1

11

Small-scale

0.437

High

1316680

MIPT3
TRAF3-interacting protein 1

1

3

High-throughput

0.417

High

62558

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.407

High

114503

H0YDF6
NHS like 1

1

6

High-throughput

0.407

High

1316696

S39AD
Zinc transporter ZIP13

1

1

High-throughput

0.407

High

1316707

VIAAT
Vesicular inhibitory amino acid transporter

1

1

High-throughput

0.407

High

1316727

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.328

High

1220016

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

1316685

CV015
Uncharacterized protein C22orf15

2

0

High-throughput

0.316

High

844826

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.279

Low

1239513

ZNT6
Zinc transporter 6

1

0

High-throughput

0.232

Low

1316674

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025