Protein: TDA2
Topoisomerase I damage affected protein 2

Gene: TDA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 19
UniProt ID: P40045

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0030479 - actin cortical patch
GO:0030837 - negative regulation of actin filament polymerization
GO:0043332 - mating projection tip
GO:0110131 - Aim21-Tda2 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817458

AIM21
Altered inheritance of mitochondria protein 21

7

0

Small-scale

0.719

High

703771

CAPZA
F-actin-capping protein subunit alpha

3

0

High-throughput

0.638

High

817454

TDA2
Topoisomerase I damage affected protein 2

2

0

Small-scale

0.598

High

817455

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.588

High

562959

CAPZB
F-actin-capping protein subunit beta

2

0

Small-scale

0.569

High

817460

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.518

High

709787

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

817459

BBC1
Myosin tail region-interacting protein MTI1

1

0

High-throughput

0.458

High

817464

BSP1
F-actin capping regulator BSP1

1

0

High-throughput

0.458

High

545022

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

579468

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.426

High

817456

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

817461

YD366
Uncharacterized protein YDR366C

1

0

High-throughput

0.282

High

817457

YIP2
Uncharacterized protein YIL152W

1

0

High-throughput

0.269

Low

817462

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.269

Low

707207

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

817463

YD445
Putative uncharacterized protein YDR445C

1

0

High-throughput

0.238

Low

817465

YDL96
Putative uncharacterized protein YDL196W

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025